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Scientists explore why Leishmania parasites develop resistance against existing drugs

Leishmaniasis is one of the most underreported and insufficiently monitored diseases in the world affecting mainly the poorest and most disadvantaged people on the Indian Subcontinent, Latin America and East Africa. The disease is caused by tiny parasites, the Leishmania, and transmitted by the bite of an infected sandfly.

14 May 2014

Eagle Pharmaceuticals total revenue increases by $2.5 million for Q2 2014

Eagle Pharmaceuticals, Inc. today announced its financial results for the three-month period ended March 31, 2014. This marks the first period for which Eagle is reporting financial results as a public company.

14 May 2014

Intensive insulin treatment improves survival for diabetic heart attack patients

Long-term follow-up of the DIGAMI 1 trial – a landmark study of type 2 diabetes in Sweden – shows that intensive insulin treatment prolonged life by more than 2 years in patients with diabetes after a heart attack, compared with standard treatment for diabetes, reports Dr Viveca Ritsinger from the Unit of Cardiology of the Department of Medicine, Karolinska Institute, Stockholm, Sweden and colleagues in The Lancet Diabetes & Endocrinology.

14 May 2014

Salk scientists explore earliest detectable changes in the brain that lead to schizophrenia

Using new stem cell technology, scientists at the Salk Institute have shown that neurons generated from the skin cells of people with schizophrenia behave strangely in early developmental stages, providing a hint as to ways to detect and potentially treat the disease early.

14 May 2014

Smart drugs have lasting side-effects on young people's brain

Over a million American students misuse prescription drugs or take illegal stimulants to increase their attention span, memory, and capacity to stay awake. Such "smart drugs" become more and more popular due to peer pressure, stricter academic requirements, and the tight job market. But young people who misuse them risk long-term impairments to brain function, warn Kimberly Urban at the University of Delaware and Wen-Jun Gao at Drexel University College of Medicine, USA, in a NIH-funded review published in the open-access journal Frontiers in Systems Neuroscience.

14 May 2014

USC/NYU researchers develop small molecule that interferes with cancer progression with minimal side effects

A team of researchers from USC and NYU has developed and patented a small molecule that interferes with cancer progression with minimal side effects.

14 May 2014

Several medications can help people with alcohol use disorders quit drinking

Several medications can help people with alcohol use disorders maintain abstinence or reduce drinking, according to research from the University of North Carolina at Chapel Hill.

14 May 2014

Scientists identify two new genes that lead to more aggressive forms of prostate cancer

A study by the Columbia University Nova York, in collaboration with the Catalan Institute of Oncology , Belvitge Biomedical Research Institute (ICO-IDIBELL) has identified two new genes that lead to more aggressive forms of prostate cancer.

14 May 2014

SGK1 enzyme, asthma and cancer therapies: an interview with Dr. Jonathan D. Powell, Johns Hopkins Kimmel Cancer Center

SGK1 stands for serum/glucocorticoid-regulated kinase 1. SGK1 is a member of the AGC kinase family, which is a huge family of kinases.

13 May 2014

C-section delivery, early antibiotic treatment linked to eosinophilic esophagitis in children

Children delivered by cesarean section and those given antibiotics during early infancy appear more prone to developing allergic inflammation of the esophagus — the muscular tube that connects the mouth to the stomach — according to results of a study by investigators from the Johns Hopkins Children’s Center and Harvard Medical School.

13 May 2014

Parent disapproval linked to lower rate of drug misuse among teens

Parents' attitudes toward substance use may help to explain observed racial/ethnic variations in prescription drug misuse among teens, reports a study in the May Journal of Developmental & Behavioral Pediatrics, the official journal of the Society for Developmental and Behavioral Pediatrics.

13 May 2014

Johns Hopkins scientists identify genetic marker associated with development of obsessive-compulsive disorder

A group of researchers led by Johns Hopkins scientists say they have identified a genetic marker that may be associated with the development of obsessive-compulsive disorder (OCD), whose causes and mechanisms are among the least understood among mental illnesses.

13 May 2014

Pro-urokinase promotes angiogenesis but does not reduce neuronal apoptosis in infarcted cerebral tissue

Among the drugs used for acute ischemic stroke, recombinant tissue plasminogen activator is widely accepted internationally. In China, urokinase has been widely used for thrombolysis after acute ischemic stroke.

13 May 2014

Researchers identify target molecules for development of new allergy drugs

Researchers have identified several target molecules which are suitable for the development of new allergy drugs. The Journal of Allergy and Clinical Immunology, the most prestigious journal in the field of allergology, has recently published an extensive review article on the prospects of drug therapy for allergy. Completed in a large-scale EU project, the lead author of the review article is Professor Ilkka Harvima of the University of Eastern Finland and Kuopio University Hospital.

13 May 2014

Study reveals 70% of patients with diabetic retinopathy will develop macular edema

In Mexico, at least 14 million people have developed macular edema due to diabetes (DME), which like retinopathy affects central vision and can lead to blindness if not treated early .

13 May 2014

New study presents novel strategy for treating multiple myeloma

A new study by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James) provides evidence that genetically modifying immune cells might effectively treat multiple myeloma, a disease that remains incurable and will account for an estimated 24,000 new cases and 11,100 deaths in 2014

13 May 2014

Study on aspirin may offer hope to develop drugs that promote healing of chronic wounds in humans

In addition to its known capacity to promote bleeding events, aspirin also inhibits wound healing. New research published in The Journal of Experimental Medicine now describes how aspirin acts on key skin cells called keratinocytes, delaying skin repair at wound sites.

13 May 2014

Drugs News and Research

Scientists explore why Leishmania parasites develop resistance against existing drugs

Eagle Pharmaceuticals total revenue increases by $2.5 million for Q2 2014

Intensive insulin treatment improves survival for diabetic heart attack patients

Salk scientists explore earliest detectable changes in the brain that lead to schizophrenia

Smart drugs have lasting side-effects on young people's brain

USC/NYU researchers develop small molecule that interferes with cancer progression with minimal side effects

Several medications can help people with alcohol use disorders quit drinking

Scientists identify two new genes that lead to more aggressive forms of prostate cancer

SGK1 enzyme, asthma and cancer therapies: an interview with Dr. Jonathan D. Powell, Johns Hopkins Kimmel Cancer Center

C-section delivery, early antibiotic treatment linked to eosinophilic esophagitis in children

Parent disapproval linked to lower rate of drug misuse among teens

Johns Hopkins scientists identify genetic marker associated with development of obsessive-compulsive disorder

Pro-urokinase promotes angiogenesis but does not reduce neuronal apoptosis in infarcted cerebral tissue

Researchers identify target molecules for development of new allergy drugs

Study reveals 70% of patients with diabetic retinopathy will develop macular edema

New study presents novel strategy for treating multiple myeloma

Study on aspirin may offer hope to develop drugs that promote healing of chronic wounds in humans

Medicare roundup: Alabama pain clinic spending 'hotspot'; quality improvement program scrutinized

Melbourne researchers find link between necroptosis and inflammatory disease

Researchers identify several target molecules suitable for development of new allergy drugs

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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