Atherosclerosis News and Research

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Atherosclerosis is the progressive buildup of plaque - the fatty deposits and other cells - in the inner walls of the arteries. The condition is a consequence of elevated cholesterol and for many it's a silent disease, with no visible signs or symptoms. The disease can begin in early adulthood and continues to progress for the rest of a person's life. Despite the serious nature of atherosclerosis, many people do not understand how it develops and progresses.

New way of delivering corrective genes holds promise for hereditary diseases of the heart

A new way of delivering corrective genes with a single injection into a vein holds promise for long-lasting treatments of hereditary diseases of the heart, University of Florida researchers report.

6 Aug 2006

New research may solve problem of vessels re-closing after angioplasty

Through studying pigeons with genetic heart disease, researchers at Wake Forest University School of Medicine have discovered a clue about why some patients' heart vessels are prone to close back up after angioplasty.

6 Aug 2006

Mechanics of atherosclerosis

Atherosclerotic narrowing and hardening of coronary arteries typically appear first at vessel branches, and a study in the October issue of Cellular Signalling reports that the type of mechanical stretching found at those branches activates a cellular protein known to damage cells.

12 Jul 2006

Study shows high survival for patients with torn aortas who get surgery

Nearly three years ago, actor John Ritter collapsed on the set of his sitcom, the victim of a rare but often deadly condition called aortic dissection - a tear in the largest blood vessel in the body.

11 Jul 2006

Don't smoke and eat fish to keep your sight later in life

New research from Australia and the U.S. into Age-related Macular Degeneration, has found that cigarette smoking increases the risk but eating fish protects against it, and hormone replacement therapy makes no difference whatsoever.

10 Jul 2006

Cell survival depends on chromosome integrity

UCLA researchers report that thousands of genes behave differently in the same organs of males and females - something never detected to this degree.

9 Jul 2006

Grandma was right after all, eating lots of veggies is good for you

It seems grandma was right after all and eating lots of veggies is good for you.

19 Jun 2006

Vegetables may reduce hardening of arteries

New research suggests one reason vegetables may be so good for us - a study in mice found that a mixture of five common vegetables reduced hardening of the arteries by 38 percent compared to animals eating a non-vegetable diet.

18 Jun 2006

Know your fats because now trans fats are the bad guys

A new study has found that trans fats redistribute body fat to the abdomen, creating the deadly "apple" body shape and it can happen on a calorie-controlled diet.

14 Jun 2006

Japanese researchers using PET imaging detect the beginnings of atherosclerosis

Using positron emission tomography (PET), the medical isotope 15O-water and cold pressor tests, Japanese researchers were able to detect the beginnings of atherosclerosis - before the disease became clinically evident.

9 Jun 2006

Gene mutation potentially involved in breast cancer initiation

Researchers have found evidence suggesting that a mutation in a gene that normally helps block the formation of breast tumors could play a role in the initiation of a major form of breast cancer.

6 Jun 2006

Common genetic variation makes some people more susceptible to coronary heart disease

Caucasians who carry this polymorphism, named K55R, were at significantly higher risk of coronary heart disease, independent of other risk factors, like cigarette smoking, diabetes, and hypertension.

16 May 2006

K55R polymorphism gene variation linked to coronary heart disease

New research at the National Institute of Environmental Health Sciences, part of the National Institutes of Health, found that a common genetic variation makes some people more susceptible to coronary heart disease (CHD).

12 May 2006

Smokers more likely to receive jolt from defibrillators

If some patients with heart disease don't take their doctor's advice to quit smoking, they are probably going to get "shocking" reminders.

8 May 2006

Urgent effort underway to learn how diabetes increases heart disease risk

A researcher at the University of Rochester Medical Center has won the 2006 Thomas R. Lee Career Development Award from the American Diabetes Association (ADA), which includes an $842,400 grant to study how diabetes dramatically increases risk for cardiovascular disease.

8 May 2006

Lung function decline and outcomes in an adult population

Rapid lung function decline significantly increases the risk of death and hospitalization for individuals with chronic obstructive pulmonary disease (COPD).

3 May 2006

Higher levels of education associated with a lower prevalence of coronary artery calcium

...an indicator of subclinical atherosclerosis (thickening and plaque deposits in the artery walls) among young adults and those in early middle age, according to a study in the April 19 issue of JAMA: The Journal of the American Medical Association.

19 Apr 2006

Higher levels of education are associated with a lower prevalence of coronary artery calcium

...an indicator of low-grade or asymptomatic atherosclerosis (thickening and plaque deposits in the artery walls) among young adults and those in early middle age, according to a study in the April 19 issue of JAMA: The Journal of the American Medical Association.

18 Apr 2006

Excessive adiposity, calorie restriction, and aging

Can eating a low-calorie yet nutritionally balanced diet extend human life? Preliminary research suggests it might, so researchers at Washington University School of Medicine in St. Louis are launching a long-term study to find out.

16 Apr 2006