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New process separates beneficial glucocorticoids from unwanted side-effects

A collaboration led by Scripps Research has developed a way to separate the beneficial anti-inflammatory properties of a group of steroids called glucocorticoids from some of their unwanted side-effects, through an optimization process they named "ligand class analysis."

3 Feb 2021

Researchers find possible cause for self-destructive immune system attacks in autoimmune diseases

Autoimmune diseases, in which the body's own immune system attacks healthy tissue, can be life-threatening and can impact all organs.

2 Feb 2021

Study explains why people of African descent are less likely to find bone marrow donors

A paper by a multidisciplinary team of scientists affiliated with various Brazilian institutions, including the University of São Paulo (USP) and the National Cancer Institute (INCA), shows that people of African descent are less likely to find a donor in the National Register of Voluntary Bone Marrow Donors (REDOME) than people with predominantly European ancestry.

1 Feb 2021

Life-threatening genetic immunodeficiency reversed by a rare DNA change

Researchers have revealed how a rare DNA change rebalanced the immune system of patients with a life-threatening genetic immunodeficiency.

1 Feb 2021

Groundbreaking therapy may provide a new treatment modality for biofilm infections in foot ulcers

A new £1.7m project to explore using plasma jets and antimicrobial dressings to treat debilitating - and potentially deadly - wound infections launches today.

1 Feb 2021

New policy guidance outlines the benefits of Post-Fracture Care Coordination Programs

By 2025 some 500 million people will be living with osteoporosis, a chronic disease which weakens bones and leaves older adults at risk of a fragility fracture - a broken bone which typically occurs after a low-trauma fall. As a result, an estimated 13.5 million fragility fractures will occur worldwide.

1 Feb 2021

Gene panel is effective at identifying problematic genes in common leukemia

A gene panel that looks for about 10 times the number of cancer-causing genes as panels currently used to diagnose and fine-tune treatment for a variety of cancers is effective at identifying problematic genes in the most common leukemia, investigators report.

1 Feb 2021

Study reveals effective therapeutic strategy to prevent colorectal cancer progression

Nagoya University researchers and colleagues have revealed that colorectal cancer tissues contain at least two types of fibroblasts (a type of cells found in connective tissue), namely, cancer-promoting fibroblasts and cancer-restraining fibroblasts, and that the balance between them is largely involved in the progression of colorectal cancer.

30 Jan 2021

Robotic technology enables ultraprecise, customized knee replacement procedure

In a career spanning more than two decades, orthopedic surgeon Geoffrey Westrich has seen numerous advances in joint replacement surgery that benefit patients.

29 Jan 2021

Weight loss before surgery may not be beneficial for patients with knee osteoarthritis

A new University of Alberta study shows that losing weight before knee replacement surgery doesn't lead to better outcomes for patients.

28 Jan 2021

Researchers develop a simple and efficient way to generate hemogenic endothelial cells

Pioneering research into how our bodies manufacture the cells that make blood has moved us closer to regrowing tissues and organs. The findings also may let doctors grow the cells for transplantation into people to battle cancer, blood disorders and autoimmune diseases.

28 Jan 2021

4 vital health issues — not tied to Covid — that Congress addressed in massive spending bill

Late last month, before President Joe Biden took office and proposed his pandemic relief plan, Congress passed a nearly 5,600-page legislative package that provided some pandemic relief along with its more general allocations to fund the government in 2021.

28 Jan 2021

APCO launches first pan-Asia Pacific clinical standards for osteoporosis

The Asia Pacific Consortium on Osteoporosis (APCO) has today launched the first pan-Asia Pacific clinical practice standards for the screening, diagnosis, and management of osteoporosis, targeting a broad range of high-risk groups.

28 Jan 2021

Researchers figure out how the immune system keeps tabs on the brain

Alzheimer's disease, multiple sclerosis, autism, schizophrenia and many other neurological and psychiatric conditions have been linked to inflammation in the brain.

27 Jan 2021

If I have cancer, dementia or MS, should i get the covid vaccine?

As public demand grows for limited supplies of covid-19 vaccines, questions remain about the vaccines' appropriateness for older adults with various illnesses.

27 Jan 2021

New method replicates bone tissue complexity, bone remodeling processes

A multidisciplinary team of researchers at the University of Massachusetts Amherst's Institute for Applied Life Sciences (IALS) have developed a technique to replicate bone tissue complexity and bone remodeling processes.

27 Jan 2021

New compound may slow aging and age-related diseases

A compound that extends lifespan in a tiny nematode worm slows bone loss in aging mice. That surprising result comes from a longitudinal and functional study of 700 aging mice at the Buck Institute, a project that provides a treasure trove of data for researchers aiming to develop therapeutics to slow aging and age-related diseases.

27 Jan 2021

Two-drug combination approach could be effective against bone cancer

An innovative approach to treating bone tumors - starving cancer cells of the energy they need to grow - could one day provide an alternative to a commonly used chemotherapy drug without the risk of severe side effects, suggests a new study from Washington University School of Medicine in St. Louis.

27 Jan 2021

Two enzymes fuel transition from pre-cancer stem cells to leukemia stem cells

Since stem cells can continually self-regenerate, making more stem cells, and differentiate into many different specialized cell types, they play an important role in our development and health.

26 Jan 2021

Pain-free microneedle patch can capture biomarkers from interstitial fluid

Blood draws are no fun. They hurt. Veins can burst, or even roll - like they're trying to avoid the needle too, Oftentimes, doctors use blood samples to check for biomarkers of disease: antibodies that signal a viral or bacterial infection, such as SARS-CoV-2, the virus responsible for COVID-19, or cytokines indicative of inflammation seen in conditions such as rheumatoid arthritis and sepsis.

26 Jan 2021

Bone News and Research

New process separates beneficial glucocorticoids from unwanted side-effects

Researchers find possible cause for self-destructive immune system attacks in autoimmune diseases

Study explains why people of African descent are less likely to find bone marrow donors

Life-threatening genetic immunodeficiency reversed by a rare DNA change

Groundbreaking therapy may provide a new treatment modality for biofilm infections in foot ulcers

New policy guidance outlines the benefits of Post-Fracture Care Coordination Programs

Gene panel is effective at identifying problematic genes in common leukemia

Study reveals effective therapeutic strategy to prevent colorectal cancer progression

Robotic technology enables ultraprecise, customized knee replacement procedure

Weight loss before surgery may not be beneficial for patients with knee osteoarthritis

Researchers develop a simple and efficient way to generate hemogenic endothelial cells

4 vital health issues — not tied to Covid — that Congress addressed in massive spending bill

APCO launches first pan-Asia Pacific clinical standards for osteoporosis

Researchers figure out how the immune system keeps tabs on the brain

If I have cancer, dementia or MS, should i get the covid vaccine?

New method replicates bone tissue complexity, bone remodeling processes

New compound may slow aging and age-related diseases

Two-drug combination approach could be effective against bone cancer

Two enzymes fuel transition from pre-cancer stem cells to leukemia stem cells

Pain-free microneedle patch can capture biomarkers from interstitial fluid

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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