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Tiny ultrasound-powered nanorobots could offer safe, efficient way to detoxify biological fluids

Engineers at the University of California San Diego have developed tiny ultrasound-powered robots that can swim through blood, removing harmful bacteria along with the toxins they produce. These proof-of-concept nanorobots could one day offer a safe and efficient way to detoxify and decontaminate biological fluids.

31 May 2018

Highly stable DNA origami nanostructures may pave way for a plethora of biomedical applications

The DNA origami technique is a widely used method for making complex, yet well-defined nanostructures, with applications in biophysics, molecular biology, as well as drug and enzyme delivery.

31 May 2018

Study: Cellular housekeeping can help mammals live longer and healthier

Building on two decades of research, investigators at UT Southwestern have determined that "cellular housekeeping" can extend the lifespan and healthspan of mammals.

31 May 2018

New system for anti-cancer drug delivery offers hope to treat pediatric tumors

In most of the Western World, cancer is the primary cause of death in children over the age of one. Existing treatments for adult cancer patients are not particularly effective for children.

31 May 2018

Study: Disease-causing stomach bacterium shuts down energy production in host cells

Researchers report in a new study that the bacterium Helicobacter pylori - a major contributor to gastritis, ulcers and stomach cancer - resists the body's immune defenses by shutting down energy production within the cells of the stomach lining that serve as a barrier to infection.

31 May 2018

Scientists find enzyme that breaks down plasmalogens in Alzheimer's disease patients

Alzheimer's disease patients lose up to 60% of a component called plasmalogen from the membranes of the cells in their brains, but it's still not known how or why.

31 May 2018

Scientists uncover the role of the ApoE gene in Alzheimer's Disease

A study conducted at the Massachusetts Institute of Technology has identified why the ApoE4 gene increases the risk of developing Alzheimer's disease, and why the ApoE3 gene reduces the risk.

31 May 2018

Weight gain may be the result of inefficient fat metabolism

Researchers from the Karolinska Institutet have shown that protracted weight gain can, in some cases, be attributed to a reduced ability to metabolise fat.

31 May 2018

Researchers trigger natural defense mechanism to alleviate intestinal inflammation

Treating inflammatory diseases of the bowel is extremely challenging: Genes, gut microbes and disrupted immune function all contribute.

31 May 2018

Mesoblast and Cartherics form partnership to develop 'off-the-shelf' CAR-T therapies for solid cancers

Mesoblast Limited today announced that it has entered into a partnership with Cartherics Pty Ltd to develop allogeneic ‘off-the-shelf’ CAR-T cells armed with multiple targeting receptors for use in solid cancers. Off the shelf CAR-T therapies have the potential to reduce costs dramatically and open up this very effective treatment to millions of cancer patients across the world.

31 May 2018

Scientists introduce combination approach to fight cancer

For efficient cancer therapy with few side effects, the active drug should selectively attain high concentration in the tumor. In the journal Angewandte Chemie, scientists have introduced a new approach, in which two synergistic drug components are combined into a dimer.

31 May 2018

NIH study unravels how tularemia bacteria trick host cells to cause disease

Scientists from the National Institute of Allergy and Infectious Diseases--part of the National Institutes of Health--have unraveled the process by which the bacteria cause disease.

31 May 2018

Scientists identify 'hidden' driver that helps prime the anti-tumor immune response

Like exposing a crime boss whose authority has gone undetected, St. Jude Children's Research Hospital scientists have identified a hidden driver that influences production of the T cells that fight cancer and infections. The study appears today as an advance online publication in the journal Nature.

31 May 2018

Scientists engineer bi-specific antibodies that attract immune killers directly to cancer cells

Our immune system's arsenal of defenses usually protects us from cancer. But sometimes, cancer cells overwhelm or evade this elaborate defense system.

30 May 2018

FDA-approved drug for lymphoma and leukemia may help treat common type of brain tumor

New Cleveland Clinic research shows for the first time that ibrutinib, an FDA-approved drug for lymphoma and leukemia, may also help treat the most common – and deadliest – type of brain tumor.

30 May 2018

Researchers shed promising light on the origin of Alzheimer's disease

After a decade of work, a team led by Hôpital Maisonneuve-Rosemont researcher and Université de Montréal associate professor Dr. Gilbert Bernier has shed promising light on the origin of the most common and prevalent form of Alzheimer's disease, hoping to someday help mitigate or even reverse the progress of the disease.

30 May 2018

NUS researchers find novel pathway to regulate blood pressure

New and better ways to fight hypertension and low blood pressure may be in the offing, thanks to the National University of Singapore scientists' discovery of how our blood pressure is controlled.

30 May 2018

Researchers craft mathematical model to understand how cancer evolves

The concept of survival of the fittest most often applies to the competition that occurs within and between animal species, but evolutionary pressures can be found elsewhere--even in a cancerous tumor.

30 May 2018

Researchers discover key receptor molecule for flu infection

After decades of research, a research team has discovered the key receptor molecule that enhances the infection of the influenza A virus, providing a novel target for anti-flu drug development.

30 May 2018

New RNA deletion tool could help create drugs that correct genetic diseases

As scientists gain insights into which genes drive diseases, they are pursuing the next logical question: Can gene editing technologies be developed to treat or even cure those diseases? Much of that effort has focused on developing technologies such as CRISPR-Cas9, a protein-based system.

30 May 2018

B Cell News and Research

Tiny ultrasound-powered nanorobots could offer safe, efficient way to detoxify biological fluids

Highly stable DNA origami nanostructures may pave way for a plethora of biomedical applications

Study: Cellular housekeeping can help mammals live longer and healthier

New system for anti-cancer drug delivery offers hope to treat pediatric tumors

Study: Disease-causing stomach bacterium shuts down energy production in host cells

Scientists find enzyme that breaks down plasmalogens in Alzheimer's disease patients

Scientists uncover the role of the ApoE gene in Alzheimer's Disease

Weight gain may be the result of inefficient fat metabolism

Researchers trigger natural defense mechanism to alleviate intestinal inflammation

Mesoblast and Cartherics form partnership to develop 'off-the-shelf' CAR-T therapies for solid cancers

Scientists introduce combination approach to fight cancer

NIH study unravels how tularemia bacteria trick host cells to cause disease

Scientists identify 'hidden' driver that helps prime the anti-tumor immune response

Scientists engineer bi-specific antibodies that attract immune killers directly to cancer cells

FDA-approved drug for lymphoma and leukemia may help treat common type of brain tumor

Researchers shed promising light on the origin of Alzheimer's disease

NUS researchers find novel pathway to regulate blood pressure

Researchers craft mathematical model to understand how cancer evolves

Researchers discover key receptor molecule for flu infection

New RNA deletion tool could help create drugs that correct genetic diseases

Using single B cell screening to boost antibody discovery eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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