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NIH award reflects urgency of overcoming infections that resist drug treatment

The National Institute of Allergy and Infectious Diseases of the National Institutes of Health has selected infectious disease expert David Perlin, executive director of the Public Health Research Institute at Rutgers New Jersey Medical School, to lead a major research effort aimed at developing new forms of antibiotics to regain the upper hand over deadly bacteria that have become resistant to current treatments.

26 Apr 2014

SFU researchers trace evolution of HIV in North America

A study tracing the evolution of HIV in North America involving researchers at Simon Fraser University has found evidence that the virus is slowly adapting over time to its human hosts. However, this change is so gradual that it is unlikely to have an impact on vaccine design.

26 Apr 2014

Concert Pharmaceuticals reports results from CTP-499 Phase 2 trial in patients with diabetic kidney disease

Concert Pharmaceuticals, Inc. today announced 48-week results of its Phase 2 clinical trial of CTP-499 in patients with diabetic kidney disease. CTP-499, when used in addition to the standard of care, is being developed to delay the progression of these patients to end-stage renal failure, which requires dialysis or kidney transplantation.

26 Apr 2014

French researchers introduce new method to effectively control bleeding and repair tissues

Stopping bleeding, closing wounds, repairing organs—these are everyday challenges in medical and surgical practice. In the journal Angewandte Chemie, French researchers have now introduced a new method that employs gluing by aqueous nanoparticle solutions to effectively control bleeding and repair tissues. In animal tests, their approach proved easy to apply, rapid and efficient even in situations when conventional methods are traumatic or fail.

25 Apr 2014

First Edition: April 25, 2014

Today's headlines include reports about a recommendation that Oregon switch its troubled health exchange from a state-run marketplace to healthcare.gov.

25 Apr 2014

Longer looks: Terri Schiavo case; stem cell tourism in China; fall protection for the elderly

Increasingly, Big Pharma is betting on new blockbuster cancer drugs that cost billions to develop and can be sold for thousands of dollars a dose. In 2010, each of the top 10 cancer drugs topped more than $1 billion in sales, according to Campbell Alliance, a health-care consulting firm. A decade earlier, only two of them did.

25 Apr 2014

MIT researchers develop test that can rapidly assess DNA repair systems

Our DNA is under constant attack from many sources, including environmental pollutants, ultraviolet light, and radiation. Fortunately, cells have several major DNA repair systems that can fix this damage, which may lead to cancer and other diseases if not mended.

25 Apr 2014

UB research finds novel compound for treating cocaine addiction

A novel compound that targets an important brain receptor has a dramatic effect against a host of cocaine addiction behaviors, including relapse behavior, a University at Buffalo animal study has found.

25 Apr 2014

Variant of cell surface protein may help develop drugs for gastric cancer

A team of scientists led by a researcher from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore has identified the cancer specific stem cell which causes gastric cancer. This discovery opens up the possibility of developing new drugs for the treatment of this disease and other types of cancers.

25 Apr 2014

Initial treatment for brain infection caused by fungus could be treated in 3 days, say Liverpool scientists

Initial treatment for a brain infection caused by fungus could now be treated in three days, rather than two weeks, due to study by University of Liverpool scientists.

25 Apr 2014

NIAMS scientific director to receive 2014 Ross Prize in Molecular Medicine

John J. O'Shea, M.D., scientific director at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), has been named the 2014 recipient of the Ross Prize in Molecular Medicine, conferred by the Feinstein Institute's peer-reviewed, open-access journal Molecular Medicine.

25 Apr 2014

Johns Hopkins hosts World Malaria Day to combat malaria in Africa

Johns Hopkins Bloomberg School of Public Health is bringing together some of the best minds in academia, government and faith-based organizations on World Malaria Day, Friday, April 25, 2014, for a day of discussion on leveraging community involvement to combat malaria in Africa.

25 Apr 2014

CPX-351 treatment leads to higher chances of remission in AML patients, says study

Moffitt Cancer Center researchers say clinical trials for a new experimental drug to treat acute myeloid leukemia (AML) are very promising. Patients treated with CPX-351, a combination of the chemotherapeutic drugs cytarabine and daunorubicin, are showing better responses than patients treated with the standard drug formulation.

25 Apr 2014

Researchers uncover Noxa and MCL-1 as potential targets for small cell lung cancers therapies

Approximately 15 percent of all lung cancers are small cell lung cancers (SCLC), which grow rapidly and often develop resistance to chemotherapy. However, researchers at Virginia Commonwealth University Massey Cancer Center have revealed new insights into the mechanisms leading to this resistance that may lead to improved therapies.

25 Apr 2014

Aspirin can lower colon cancer risk among people with high levels of specific gene

The humble aspirin may have just added another beneficial effect beyond its ability to ameliorate headaches and reduce the risk of heart attacks: lowering colon cancer risk among people with high levels of a specific type of gene.

25 Apr 2014

TB Alliance advances first-ever TB drug regimen to global Phase 3 clinical trial

Based on positive results from earlier clinical studies, TB Alliance is advancing the first-ever drug regimen designed to treat both drug-sensitive and some forms of multi-drug resistant tuberculosis (TB) to a global Phase 3 clinical trial.

25 Apr 2014

State highlights: Ohio hospital merger struck down; Okla. abortion drug use limited; Calif. exchange and felons

A federal appeals court on Tuesday ordered a major health system in northwest Ohio to unwind its merger with a local hospital on antitrust grounds. The unanimous decision by a three-judge panel of the Sixth U.S. Circuit Court of Appeals in Cincinnati comes amid growing concerns about hospital mergers and their effect on prices against the backdrop of America's health care upheaval (Gershman, 4/22).

25 Apr 2014

Two sedative drugs effectively treat prolonged seizures in children

The sedative drugs diazepam (Valium) and lorazepam (Ativan) are equally effective in treating the prolonged seizures known as status epilepticus in children, according to a randomized, controlled study by a multi-institution team of researchers with the Pediatric Emergency Care Applied Research Network, including an expert from the Perelman School of Medicine at the University of Pennsylvania.

25 Apr 2014

Viewpoints: Health spending ready to start climbing again; Cruz's 'nightmare' comes true

Standing before a roomful of economists, policy makers and health care experts earlier this month, Amitabh Chandra, director of Health Policy Research at Harvard's Kennedy School of Government, closed a presentation about the slowdown in health care spending over the last decade by citing an article in The New York Times.

25 Apr 2014

Enhanced recovery approach used for colorectal surgery cut hospital stays

Changes in managing patients before, during and after colorectal surgery cut hospital stays by two days and reduced readmission rates, according to researchers who led a study of the approach at Duke University Hospital.

25 Apr 2014

Drugs News and Research

NIH award reflects urgency of overcoming infections that resist drug treatment

SFU researchers trace evolution of HIV in North America

Concert Pharmaceuticals reports results from CTP-499 Phase 2 trial in patients with diabetic kidney disease

French researchers introduce new method to effectively control bleeding and repair tissues

First Edition: April 25, 2014

Longer looks: Terri Schiavo case; stem cell tourism in China; fall protection for the elderly

MIT researchers develop test that can rapidly assess DNA repair systems

UB research finds novel compound for treating cocaine addiction

Variant of cell surface protein may help develop drugs for gastric cancer

Initial treatment for brain infection caused by fungus could be treated in 3 days, say Liverpool scientists

NIAMS scientific director to receive 2014 Ross Prize in Molecular Medicine

Johns Hopkins hosts World Malaria Day to combat malaria in Africa

CPX-351 treatment leads to higher chances of remission in AML patients, says study

Researchers uncover Noxa and MCL-1 as potential targets for small cell lung cancers therapies

Aspirin can lower colon cancer risk among people with high levels of specific gene

TB Alliance advances first-ever TB drug regimen to global Phase 3 clinical trial

State highlights: Ohio hospital merger struck down; Okla. abortion drug use limited; Calif. exchange and felons

Two sedative drugs effectively treat prolonged seizures in children

Viewpoints: Health spending ready to start climbing again; Cruz's 'nightmare' comes true

Enhanced recovery approach used for colorectal surgery cut hospital stays

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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