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Researchers use massive sequencing methods to identify rare genetic bone disorder

Researchers of the "Cell Biology and Physiology-LABRET" group of the University of Malaga (UMA), together with the Networking Biomedical Research Center in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), have described a new genetic skeletal disorder based on a precision medicine strategy.

22 Dec 2020

Novel 3D maps show how genes interact in several types of immune cells

The COVID-19 pandemic has highlighted how our small genetic differences can have a tremendous effect on how our bodies respond to disease.

22 Dec 2020

Immune-inflammatory mediators indicate that rejection and tissue injury can be avoided with drugs

Immune inflammatory mediators are critical in pathology, transplantation, and regenerative medicine, scientists report in The American Journal of Pathology

22 Dec 2020

Researchers establish BRIDGES program to synergize diagnostic efforts, patient outcome management

For over 20 years, the Genetics Service at the KK Women's and Children's Hospital (KKH) has been providing clinical care to patients with genetic disorders.

22 Dec 2020

Study examines effect of COVID-19 on the well-being of Colorado workers

As the pandemic was starting to take hold, researchers from the Center for Health, Work & Environment (CHWE) at the Colorado School of Public Health (ColoradoSPH) performed a study to better understand the impact of COVID-19 on the well-being of workers in Colorado.

21 Dec 2020

Study sheds new light on immune system interactions with cancer

Cancers like melanoma are hard to treat, not least because they have a varied bag of tricks for defeating or evading treatments.

21 Dec 2020

Researchers have a promising lead on COVID-19 treatment

By taking a lesson from prostate cancer, researchers now have a promising lead on treatment for COVID-19. Two proteins, ACE2 and TMPRSS2, help the coronavirus gain entry and replicate within cells. TMPRSS2 is well-known to Arul Chinnaiyan, M.D., Ph.D. His lab discovered that TMPRSS2 fuses with the ETS gene to drive more than half of all prostate cancers. They also knew that TMPRSS2 was regulated by the androgen receptor.

21 Dec 2020

Community-based testing sites were key in minimizing exposure to COVID-19 virus

A new study looking at the results of testing children for COVID-19 through a Children's National Hospital community-based testing site found that one in four patients had a positive test.

21 Dec 2020

Study suggests effective mitigation strategies to prevent COVID-19 cases in college campus

As colleges and universities consider strategies for the spring semester to keep COVID-19 cases down, a study conducted by experts in epidemic modeling may help shed light on what mitigation strategies may be most effective, both in terms of infections prevented and cost.

21 Dec 2020

Discovery reveals new type of brain cell sensitive to distance and direction of objects

The existence of GPS-like brain cells, which can store maps of the places we've been, like our kitchen or holiday destination, was already widely known, but this discovery shows there is also a type of brain cell sensitive to the distance and direction of objects that can store their locations on these maps.

21 Dec 2020

Study provides new insights into the molecular underpinnings of Duchenne muscular dystrophy

A UT Southwestern research team has catalogued gene activity in the skeletal muscle of mice, comparing healthy animals to those carrying a genetic mutation that causes Duchene muscular dystrophy (DMD) in humans.

21 Dec 2020

Researchers explore why seizures happen in a subset of MS patients

A research team at the University of California, Riverside School of Medicine has identified a pathway involving astrocytes, a class of central nervous system support cells, that could shed light on why seizures happen in a subset of multiple sclerosis, or MS, patients.

21 Dec 2020

Absence of anti-tumor protein may cause resistance to EGFR-targeting therapies

The absence of a protein that works to prevent tumor formation may explain why some patients are resistant to a common cancer therapy, according to Penn State College of Medicine researchers.

21 Dec 2020

Early shutdown suppressed excess pandemic deaths in California

Nearly 20,000 more Californians died in the first six months of the pandemic than would have been expected to die in a normal year, with a disproportionate number of those deaths occurring among older adults, Black or Latino residents, or those who had not completed high school, according to an analysis by researchers at UC San Francisco.

21 Dec 2020

Sex-specific difference could prevent Alzheimer's treatment from working in females

A University of Ottawa study has found a specific Alzheimer's treatment is effective in male and not female mice, providing a window into the biology of the disease and the effectiveness of targeted treatments.

21 Dec 2020

Researchers demonstrate potential preventive treatment for Crohn's disease

A potential preventive treatment for Crohn's disease, a form of inflammatory bowel disease, has been demonstrated in a mouse model and using immune-reactive T cells from patients with Crohn's disease.

21 Dec 2020

Research reveals development stages of plaques in Alzheimer's disease

One cannot simply look inside someone else’s head. This makes it difficult to understand what is happening in the brains of people with dementia. A new method offers insights.

21 Dec 2020

Arthritis drug may be effective in treating immunotherapy-related heart complication

A drug typically prescribed for rheumatoid arthritis may also be effective in treating a rare but potentially deadly heart complication some cancer patients experience after taking immunotherapies, according to a study published in Cancer Discovery and co-led by investigators at Vanderbilt University Medical Center.

21 Dec 2020

COVID-19: Meta-analysis unveils adversely affected biological processes in infected lung cells

The researchers Wasco Wruck and Prof. James Adjaye from the Institute of Stem Cell Research and Regenerative Medicine, Medical Faculty of Heinrich-Heine-University Duesseldorf, Germany, employed a bioinformatic approach on transcriptome data pertaining to human lung epithelial cells infected with SARS-CoV-2.

21 Dec 2020

‘Nine months into it, the adrenaline is gone and it’s just exhausting’

In March, during the first week of the San Francisco Bay Area's first-in-the-nation stay-at-home order, KHN spoke with emergency department physicians working on the front lines of the burgeoning COVID-19 pandemic.

21 Dec 2020

Medicine News and Research

Researchers use massive sequencing methods to identify rare genetic bone disorder

Novel 3D maps show how genes interact in several types of immune cells

Immune-inflammatory mediators indicate that rejection and tissue injury can be avoided with drugs

Researchers establish BRIDGES program to synergize diagnostic efforts, patient outcome management

Study examines effect of COVID-19 on the well-being of Colorado workers

Study sheds new light on immune system interactions with cancer

Researchers have a promising lead on COVID-19 treatment

Community-based testing sites were key in minimizing exposure to COVID-19 virus

Study suggests effective mitigation strategies to prevent COVID-19 cases in college campus

Discovery reveals new type of brain cell sensitive to distance and direction of objects

Study provides new insights into the molecular underpinnings of Duchenne muscular dystrophy

Researchers explore why seizures happen in a subset of MS patients

Absence of anti-tumor protein may cause resistance to EGFR-targeting therapies

Early shutdown suppressed excess pandemic deaths in California

Sex-specific difference could prevent Alzheimer's treatment from working in females

Researchers demonstrate potential preventive treatment for Crohn's disease

Research reveals development stages of plaques in Alzheimer's disease

Arthritis drug may be effective in treating immunotherapy-related heart complication

COVID-19: Meta-analysis unveils adversely affected biological processes in infected lung cells

‘Nine months into it, the adrenaline is gone and it’s just exhausting’

Everything there is to know about biosimilars eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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