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Aetna raises earnings outlook

In other market news, coverage continues of the cost and effectiveness of Sovaldi, a new drug to treat hepatitis C, and the related earnings gained by Gilead Sciences, its manufacturer.

25 Apr 2014

Community-based structured weight loss program improves diabetes symptoms

Weight loss and control of blood sugar can reduce the risk of complications in patients with diabetes but this is difficult for many to achieve. A University of California, San Diego School of Medicine randomized controlled trial of obese adults with type 2 diabetes suggests that participants enrolled in a community-based structured weight loss program are able to shed more pounds, improve blood sugar control and reduce or eliminate insulin use and other medications compared to a control group.

25 Apr 2014

Cook Medical's Instinct Endoscopic Hemoclip now available to gastroenterologists

The Instinct Endoscopic Hemoclip is now available to gastroenterologists in major global markets. The clip is used to stop gastrointestinal (GI) tract bleeding, which is a condition that can be challenging to treat because of the variations among bleeds.

From COOK MEDICAL INC. 23 Apr 2014

Tolero Pharmaceuticals' Alvocidib gets Orphan Drug Designation for acute myeloid leukemia treatment

Tolero Pharmaceuticals, Inc., a clinical-stage company developing treatments for serious hematological diseases, today announced that the U.S. Food and Drug Administration has granted Orphan Drug designation for Alvocidib for the treatment of patients with acute myeloid leukemia (AML).

23 Apr 2014

Nearly 179 million cases of acute diarrhea occur each year in the U.S.

In the United States, approximately 179 million cases of acute diarrhea occur each year, and most of those cases are entirely preventable, a researcher from The University of Texas Health Science Center at Houston concluded in a New England Journal of Medicine review article.

23 Apr 2014

Captisol-enabled Melphalan meets primary end points in phase 2 pivotal trial

Spectrum Pharmaceuticals, a biotechnology company with fully integrated commercial and drug development operations with a primary focus in Hematology and Oncology, today announced that its pivotal trial of Captisol-enabled (propylene glycol-free) Melphalan met its primary end points.

23 Apr 2014

Nuvo Research collaborates with Ferndale to develop 2 topical dermatology products

Nuvo Research Inc., a specialty pharmaceutical company with a diverse portfolio of topical and immunology products, today announced a collaboration involving Ferndale Laboratories, Inc. and a leading Contract Research Organization with significant dermatology experience to develop two topical dermatology products based on Nuvo's patented Multiplexed Molecular Penetration Enhancer technology.

23 Apr 2014

HemoShear announces research collaboration with Medivir

HemoShear, LLC, the human disease biology company, today announced research collaboration with Medivir AB of Stockholm, Sweden, an emerging research-based pharmaceutical company focused on infectious diseases.

23 Apr 2014

Alexion Pharmaceuticals obtains orphan drug designation from EC for Soliris

Alexion Pharmaceuticals, Inc. today announced that the European Commission has granted an orphan drug designation (ODD) to Soliris (eculizumab), a first-in-class terminal complement inhibitor, for the prevention of graft rejection following solid organ transplantation. Graft rejection can cause severe injury to the transplanted organ and is a significant barrier to successful transplantation.

23 Apr 2014

First Edition: April 23, 2014

Today's headlines include a range of health policy news reports, including developments related to the health law, to the marketplace and at the state level.

23 Apr 2014

Report recommends that medical insurers use prescription monitoring data to reduce opioid abuse

The Prescription Drug Monitoring Program Center of Excellence at Brandeis University has issued a ground-breaking report recommending that medical insurers use prescription monitoring data to reduce the overdoses, deaths and health care costs associated with abuse of opioids and other prescription drugs.

23 Apr 2014

Exposure to microgravity can simulate aging for immune cells

Telling someone to "act your age" is another way of asking him or her to behave better. Age, however, does not always bring improvements.

23 Apr 2014

Study suggests that variant of cell surface protein is ideal target to treat gastric cancer

New study by the Cancer Science Institute of Singapore and National University Hospital Singapore suggests that a variant of a cell surface protein is an ideal target for developing drugs to treat gastric cancer

23 Apr 2014

Viewpoints: The case against Jenny Mccarthy's vaccine stand; apathy on HIV; defeating Alzheimer's

What do you call someone who sows misinformation, stokes fear, abets behavior that endangers people's health, extracts enormous visibility from doing so and then says the equivalent of "Who? Me?" I'm not aware of any common noun for a bad actor of this sort. But there's a proper noun: Jenny McCarthy (Frank Bruni, 4/21).

23 Apr 2014

Scientists develop DNA nanodevices that survive body's immune defenses

It's a familiar trope in science fiction: In enemy territory, activate your cloaking device. And real-world viruses use similar tactics to make themselves invisible to the immune system.

23 Apr 2014

Experts must develop preventative strategies for drug-related morbidity, says researcher

Twelve percent of adults in Sweden have diseases related to their use of medicines. But in four cases of ten it would have been possible to avoid the undesired effects.

23 Apr 2014

Stronger incentives for medical innovators can reduce health care spending, say researchers

To help rein in massive health care spending, a new RAND study concludes that U.S. policy makers should urgently find ways to incentivize pharmaceutical companies and device makers to develop products that produce more value.

23 Apr 2014

State highlights: Tenn. may send addicted moms to jail; Hawaii autism coverage; Florida medical marijuana

Pregnant women addicted to illegal narcotics or prescription pain pills could soon be jailed in Tennessee under a bill awaiting the governor's signature.

23 Apr 2014

UT Southwestern researchers identify potential new treatment for depression

Researchers at UT Southwestern Medical Center are making breakthroughs that could benefit people suffering from depression.

23 Apr 2014

Johns Hopkins scientists find a way to prevent atherosclerosis

Working with mice and rabbits, Johns Hopkins scientists have found a way to block abnormal cholesterol production, transport and breakdown, successfully preventing the development of atherosclerosis, the main cause of heart attacks and strokes and the number-one cause of death among humans. The condition develops when fat builds inside blood vessels over time and renders them stiff, narrowed and hardened, greatly reducing their ability to feed oxygen-rich blood to the heart muscle and the brain.

23 Apr 2014

Drugs News and Research

Aetna raises earnings outlook

Community-based structured weight loss program improves diabetes symptoms

Cook Medical's Instinct Endoscopic Hemoclip now available to gastroenterologists

Tolero Pharmaceuticals' Alvocidib gets Orphan Drug Designation for acute myeloid leukemia treatment

Nearly 179 million cases of acute diarrhea occur each year in the U.S.

Captisol-enabled Melphalan meets primary end points in phase 2 pivotal trial

Nuvo Research collaborates with Ferndale to develop 2 topical dermatology products

HemoShear announces research collaboration with Medivir

Alexion Pharmaceuticals obtains orphan drug designation from EC for Soliris

First Edition: April 23, 2014

Report recommends that medical insurers use prescription monitoring data to reduce opioid abuse

Exposure to microgravity can simulate aging for immune cells

Study suggests that variant of cell surface protein is ideal target to treat gastric cancer

Viewpoints: The case against Jenny Mccarthy's vaccine stand; apathy on HIV; defeating Alzheimer's

Scientists develop DNA nanodevices that survive body's immune defenses

Experts must develop preventative strategies for drug-related morbidity, says researcher

Stronger incentives for medical innovators can reduce health care spending, say researchers

State highlights: Tenn. may send addicted moms to jail; Hawaii autism coverage; Florida medical marijuana

UT Southwestern researchers identify potential new treatment for depression

Johns Hopkins scientists find a way to prevent atherosclerosis

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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