Malignant News and Research

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Online skin cancer detection training course improves physicians skill levels

Primary care physicians who took an online training course about skin cancer detection significantly improved their skill to properly diagnose and manage benign and malignant lesions, according to a national study from Henry Ford Hospital in Detroit.

8 Nov 2013

Elsevier publishes position statement by EMAS in Maturitas on topic of fertility preservation

Elsevier, a world-leading provider of scientific, technical and medical information products and services, today announced the publication of a position statement by the European Menopause and Andropause Society (EMAS) in the journal Maturitas on the topic of fertility preservation.

7 Nov 2013

New study uses genomic sequencing to develop treatments for castration-resistant prostate cancer

A new study at Mayo Clinic is using genomic sequencing to develop customized treatments for men with castration-resistant prostate cancer, a progressive and incurable stage of prostate cancer, which no longer responds to hormone therapies that stop or slow testosterone production.

7 Nov 2013

Researchers use machine learning approach to accurately diagnose breast cancer

Software that can recognize patterns in data is commonly used by scientists and economics. Now, researchers in the US have applied similar algorithms to help them more accurately diagnose breast cancer.

6 Nov 2013

Researchers identify factor that promotes metastasis of colon tumors

Tumors become highly malignant when they acquire the ability to colonize other tissues and form metastases. Researchers at Ludwig-Maximilians-Universitaet (LMU) in Munich have identified a factor that promotes metastasis of colon tumors - and presents a possible target for therapy.

5 Nov 2013

Neurosurgeons use minimally-invasive technique to remove brain tumor

More than two decades ago, Ryan Vincent had open brain surgery to remove a malignant brain tumor, resulting in a lengthy hospital stay and weeks of recovery at home.

5 Nov 2013

Scientists identify new algorithm to distinguish two subtypes of malignant melanoma

Scientists of the University of Ulm and Columbia University have discovered a diagnostic algorithm to distinguish two subtypes of malignant melanoma. Desmoplastic and spindle cell melanoma may look alike - they often resemble little scars or retractions of the skin - but differ in prognosis and therapeutic options.

4 Nov 2013

LMU researchers identify a factor that promotes metastasis of colon tumors

Tumors become highly malignant when they acquire the ability to colonize other tissues and form metastases. Researchers at Ludwig-Maximilians-Universitaet in Munich have identified a factor that promotes metastasis of colon tumors - and presents a possible target for therapy.

4 Nov 2013

Immunocore’s Phase IIa clinical trial for IMCgp100 in melanoma initiates in the UK and USA

Immunocore Limited, the Oxford-based biotechnology company developing novel biological drugs to treat cancer and viral disease, announced that its most advanced ImmTAC drug, IMCgp100 for the treatment of late stage melanoma, has reached Maximum Tolerated Dose (MTD) and the dose escalation part of this Phase I clinical study has been completed. The company has now initiated a Phase IIa clinical trial in the UK and USA.

1 Nov 2013

EZH2 protein may aid prognostication in resected NSCLC

A protein called “enhancer of zeste homolog-2” is frequently expressed in non-small-cell lung cancer and may have prognostic value following surgical resection, US researchers believe.

30 Oct 2013

Study suggests neural stem cells have tendency for malignant transformation

Although it is believed that glioma is derived from brain tumor stem cells, the source and molecular signal pathways of these cells are still unclear.

30 Oct 2013

Janssen submits Marketing Authorization Application for Ibrutinib

Janssen-Cilag International NV (Janssen) announced today it has submitted a Marketing Authorization Application (MAA) to the European Medicines Agency (EMA) for ibrutinib for the treatment of adult patients with relapsed or refractory chronic lymphocytic leukemia (CLL)/small lymphocytic leukemia (SLL) or relapsed or refractory mantle cell lymphoma (MCL), two forms of blood cancer.

30 Oct 2013

Blood levels of microRNAs may serve as diagnostic tool for thyroid cancer, but more research needed

A new analysis has found that the presence of short segments of genetic material (known as microRNA) within papillary thyroid cancer tumors suggests a likelihood of recurrence after patients undergo surgery.

29 Oct 2013

Penn Medicine researchers show predictive power of overlooked lymph nodes

For the first time, researchers from the Perelman School of Medicine at the University of Pennsylvania have shown the predictive power of a group of overlooked lymph nodes--known as the posterior intercostal lymph nodes--that could serve as a better tool to stage and ultimately treat patients with malignant pleural mesothelioma.

29 Oct 2013

VisionGate's Cell-CT platform can detect lung cancer in sputum samples with high specificity

VisionGate, Inc., a company developing a revolutionary non-invasive test for the early detection of lung cancer, today reported clinical data showing that its automated 3D cell imaging platform, the Cell-CT-, can detect lung cancer in sputum samples with high sensitivity and specificity. The data was presented at the International Association for the Study of Lung Cancer 15th World Conference on Lung Cancer.

29 Oct 2013

Polaris Group reports positive results from ADI-PEG 20 Phase 2 trial for malignant pleural mesothelioma

Polaris Group announced today that positive results from a randomized Phase 2 trial of ADI-PEG 20, arginine deiminase formulated with polyethylene glycol, for the treatment of malignant pleural mesothelioma were presented at the World Conference on Lung Cancer in Sydney, Australia.

28 Oct 2013

Study shows low uptake of HPV vaccination among patients with autoimmune diseases

The number of children and young adults with autoimmune diseases receiving the HPV vaccination is profoundly low despite studies showing the vaccine to be safe and effective, according to research presented this week at the American College of Rheumatology Annual Meeting in San Diego. Given the increased incidence of HPV in people with autoimmune diseases, this research suggests that increased public health efforts are needed.

28 Oct 2013

Two related genes underlie development of two rare bone tumours in nearly 100% of patients

Scientists have made a rare discovery that allows them to attribute two types of tumour almost entirely to specific mutations that lie in two related genes.

28 Oct 2013

McGill online game expands to connect global scientific community with citizen scientists

Over the past three years, 300,000 gamers have helped scientists with genomic research by playing Phylo, an online puzzle game. Now J-r-me Waldisp-hl, the McGill computer science professor and his colleagues, who developed the game are making this crowd of players available to scientists around the globe.

25 Oct 2013

Study: Gene Expression Classifier test reduces unnecessary surgeries in thyroid nodule assessment

The latest study co-led by a CU School of Medicine researcher has confirmed that a Gene Expression Classifier (GEC) test can drastically reduce the problem of unnecessary surgeries in thyroid nodule assessment.

25 Oct 2013

Malignant News and Research

Online skin cancer detection training course improves physicians skill levels

Elsevier publishes position statement by EMAS in Maturitas on topic of fertility preservation

New study uses genomic sequencing to develop treatments for castration-resistant prostate cancer

Researchers use machine learning approach to accurately diagnose breast cancer

Researchers identify factor that promotes metastasis of colon tumors

Neurosurgeons use minimally-invasive technique to remove brain tumor

Scientists identify new algorithm to distinguish two subtypes of malignant melanoma

LMU researchers identify a factor that promotes metastasis of colon tumors

Immunocore’s Phase IIa clinical trial for IMCgp100 in melanoma initiates in the UK and USA

EZH2 protein may aid prognostication in resected NSCLC

Study suggests neural stem cells have tendency for malignant transformation

Janssen submits Marketing Authorization Application for Ibrutinib

Blood levels of microRNAs may serve as diagnostic tool for thyroid cancer, but more research needed

Penn Medicine researchers show predictive power of overlooked lymph nodes

VisionGate's Cell-CT platform can detect lung cancer in sputum samples with high specificity

Polaris Group reports positive results from ADI-PEG 20 Phase 2 trial for malignant pleural mesothelioma

Study shows low uptake of HPV vaccination among patients with autoimmune diseases

Two related genes underlie development of two rare bone tumours in nearly 100% of patients

McGill online game expands to connect global scientific community with citizen scientists

Study: Gene Expression Classifier test reduces unnecessary surgeries in thyroid nodule assessment

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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