Mouse Model News and Research

RSS

Researchers seek to understand role of novel protein in tumor metastasis

Metastasis, the process in which a tumor spreads to other parts of the body, is responsible for 90% of deaths from tumors. It is the greatest challenge to a cancer patient's survival. Metastatic spread occurs in several steps, these include that tumor cells become mobile and cross into and out of blood vessels.

8 Dec 2017

Study links canola oil consumption with worsened memory, learning ability in Alzheimer's

Canola oil is one of the most widely consumed vegetable oils in the world, yet surprisingly little is known about its effects on health.

7 Dec 2017

Hyperbaric oxygen therapy can improve pathology of Alzheimer's disease, study shows

A new Tel Aviv University study reveals that hyperbaric oxygen treatments may ameliorate symptoms experienced by patients with Alzheimer's disease.

6 Dec 2017

TUM scientists discover emergency shut-off switch for T cell Non-Hodgkin's lymphoma

Safety switches that automatically stop the device for example before it overheats are built into many electrical appliances. Cells are also equipped with such "emergency stop" functions. They make sure that a defective cell doesn't become a tumor cell.

6 Dec 2017

UT Southwestern researchers identify potential approach to suppress lethal parasitic infections

UT Southwestern Medical Center researchers have identified a chemical that suppresses the lethal form of a parasitic infection caused by roundworms that affects up to 100 million people and usually causes only mild symptoms.

5 Dec 2017

Immune-boosting drug combination may hold promise for treating ovarian cancer

Johns Hopkins Kimmel Cancer Center researchers demonstrated that mice with ovarian cancer that received drugs to reactivate dormant genes along with other drugs that activate the immune system had a greater reduction of tumor burden and significantly longer survival than those that received any of the drugs alone.

5 Dec 2017

New small-molecule drug restores brain function, memory in mouse model of Alzheimer's disease

An international team of researchers has shown that a new small-molecule drug can restore brain function and memory in a mouse model of Alzheimer's disease.

5 Dec 2017

Novel drug combination could enhance immunotherapy responses in patients with lung cancer

Johns Hopkins Kimmel Cancer Center researchers and colleagues have identified a novel drug combination therapy that could prime nonsmall cell lung cancers to respond better to immunotherapy.

30 Nov 2017

Study elucidates how lymphocytes regulate immune response after heart attacks

The damage caused by a heart attack triggers an inflammatory reaction which degrades the affected tissue. This response is orchestrated by immune cells that reside in the nearby pericardial adipose tissue, as a study by a team of Ludwig-Maximilians-Universitaet) in Munich shows.

30 Nov 2017

UT Southwestern researchers develop improved gene-editing technique to correct DMD mutations

Regenerative medicine researchers at UT Southwestern Medical Center developed an improved and simplified gene-editing technique using CRISPR/Cas9 tools to correct a common mutation that causes Duchenne muscular dystrophy.

30 Nov 2017

Scientists identify new strategies used by Helicobacter pylori to target mitochondria

Helicobacter pylori is a bacterial pathogen that colonizes the stomach of approximately half of the world's population. Infection with H. pylori is acquired in childhood and lasts for decades.

29 Nov 2017

Study provides potential explanation for increased prevalence of asthma in adult women

In childhood, asthma is more common in boys than girls. But around the time of puberty, that picture reverses. By midlife women are twice as likely as men to have asthma.

29 Nov 2017

Low levels of miR-29 could reduce susceptibility to cardiac fibrosis

Cardiac fibrosis involves an increase of connective tissue in the cardiac muscle, causing a loss of function. A team of researchers at the Technical University of Munich has now discovered that microRNA 29 (miR-29) plays an important role in the formation of tissue fibrosis.

23 Nov 2017

Research findings offer prime drug targets to treat rare liver cancer that strikes young people

After years of rigorous research, a team of scientists has identified the genetic engine that drives a rare form of liver cancer. The findings offer prime targets for drugs to treat the usually lethal disease, fibrolamellar hepatocellular carcinoma (FL-HCC), which mainly strikes adolescents and young adults.

22 Nov 2017

Liver disease in children with Alagille Syndrome caused by malformations of bile ducts

Serious liver and heart problems can affect children with Alagille Syndrome early in life. While there is as yet no cure, researchers at Karolinska Institutet in Sweden have discovered that the liver disease part of the syndrome is caused by specific malformations of the bile ducts.

21 Nov 2017

Mouse Model News and Research

Researchers seek to understand role of novel protein in tumor metastasis

Study links canola oil consumption with worsened memory, learning ability in Alzheimer's

Hyperbaric oxygen therapy can improve pathology of Alzheimer's disease, study shows

TUM scientists discover emergency shut-off switch for T cell Non-Hodgkin's lymphoma

UT Southwestern researchers identify potential approach to suppress lethal parasitic infections

Immune-boosting drug combination may hold promise for treating ovarian cancer

New small-molecule drug restores brain function, memory in mouse model of Alzheimer's disease

Novel drug combination could enhance immunotherapy responses in patients with lung cancer

Study elucidates how lymphocytes regulate immune response after heart attacks

UT Southwestern researchers develop improved gene-editing technique to correct DMD mutations

Scientists identify new strategies used by Helicobacter pylori to target mitochondria

Study provides potential explanation for increased prevalence of asthma in adult women

Low levels of miR-29 could reduce susceptibility to cardiac fibrosis

Research findings offer prime drug targets to treat rare liver cancer that strikes young people

Liver disease in children with Alagille Syndrome caused by malformations of bile ducts

Research paves way for development of vaccines against mycoplasma bacteria

Preclinical study shows clear path toward effective treatment for rare bone disease

Enterovirus vaccine protects against virus-induced diabetes in mouse model

Cancer drugs may offer new way to control high blood pressure

Drug used to prevent and treat malaria may also be effective for Zika virus

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Latest News