Precision Medicine News and Research

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Researchers identify, validate three distinct molecular subtypes of prostate cancer

In the largest study of its kind to date, researchers have identified and validated three distinct molecular subtypes of prostate cancer that correlate with distant metastasis-free survival and can assist in future research to determine how patients will respond to treatment, according to research presented today at the 58th Annual Meeting of the American Society for Radiation Oncology.

26 Sep 2016

Skin phenotype of pediatric eczema opens door for personalized treatment of AD in infants

Researchers for the first time have identified the skin phenotype of pediatric eczema or atopic dermatitis (AD) in infants, opening the door for personalized treatment approaches for young children with eczema.

23 Sep 2016

Precision medicine trial shows analysing person's DNA improves treatment options for cancer patients

A clinical trial for types of advanced cancer is the first of its kind to show that precision medicine - or tailoring treatment for individual people - can slow down the time it takes for a tumour to grow back, according to research presented at the Molecular Analysis for Personalised Therapy (MAP) conference, today (Friday).

23 Sep 2016

MSK introduces unique program to expand, streamline patient access to high-quality cancer care

In an effort to expand and streamline patient access to its high-quality cancer care, Memorial Sloan Kettering Cancer Center has introduced MSK Direct, a unique program in which MSK collaborates with external employers to simplify how their employees can engage with the institution for initial or ongoing cancer care.

22 Sep 2016

Scientists discover genomic alterations in pediatric relapsed ALL

A group of researchers from Columbia University, Rutgers University, and institutions in Europe and Japan have identified genomic alterations in pediatric relapsed acute lymphoblastic leukemia (ALL) that cause both therapy resistance and improved clinical response to multi-agent chemotherapy treatment.

22 Sep 2016

Scientists use novel theranostics technique for early thromboembolism diagnosis and treatment

Researchers from the University of Arkansas for Medical Science (USA), in collaboration with University Hospital Frankfurt and University Hospital Dresden, under the supervision of Prof. Vladimir Zharov and with the participation of Alexander Melerzanov, the dean of Department of Biological and Medical Physics (MIPT), conducted experiments on mice to detect blood clotting using photoacoustic flow-cytometry.

21 Sep 2016

CHOP researchers exploit gene discovery in severe epilepsy to identify precision treatment

An international team of researchers who discovered a new gene disorder that causes severe childhood epilepsy leveraged that finding to reduce seizures in two children.

20 Sep 2016

Leading cancer organizations publish new guidelines on postmastectomy radiotherapy

Three leading national cancer organizations today issued a joint clinical practice guideline update for physicians treating women with breast cancer who have undergone a mastectomy.

20 Sep 2016

Researchers explain novel approach for analyzing diverse immune responses

The response to infection is highly variable from one individual to another. The Milieu Intérieur consortium, coordinated by Prof. Matthew Albert (Immunobiology of dendritic cells Unit, Institut Pasteur / Inserm) and Dr Lluis Quintana-Murci (Human Evolutionary Genetics Unit, Institut Pasteur / CNRS) seek to establish the parameters that characterize the immune system of healthy individuals and its natural variability.

16 Sep 2016

Small implanted device can improve breast cancer survival by detecting cancer cells

A small device implanted under the skin can improve breast cancer survival by catching cancer cells, slowing the development of metastatic tumors in other organs and allowing time to intervene with surgery or other therapies

15 Sep 2016

Real-time MRI guidance could help target and deliver stem cell therapies

Working with animals, a team of scientists reports it has delivered stem cells to the brain with unprecedented precision by threading a catheter through an artery and infusing the cells under real-time MRI guidance.

14 Sep 2016

New molecular mechanism may explain pain relieving drug’s diverse benefits

Aspirin's ability to reduce the risk of both cardiovascular disease and colon cancer has been a welcome, yet puzzling, attribute of the pain reliever that has been a mainstay in medicine cabinets for more than 100 years.

7 Sep 2016

Nanomechanical microcantilevers can quickly detect mutations in patients with malignant melanoma

Changes in the genetic make-up of tissue samples can be detected quickly and easily using a new method based on nanotechnology.

6 Sep 2016

Respiratory viral infection triggering asthma attack in children linked to treatment failure

The results of a study conducted by Dr. Francine Ducharme, Professor in the Departments of Pediatrics and Social and Preventive Medicine at the University of Montreal, published in the medical journal The Lancet Respiratory Medicine, confirm that respiratory viral detection, not child's age, explains the high rate of hospitalization for asthma attacks in children under six.

30 Aug 2016

Could a light-listening photonics device detect skin disease? An interview with Prof. Vasilis Ntziachristos

Detection of malignant skin alterations is currently aided by optical microscopes such as dermoscopes or optical microscopes. While the latter offers high resolution, it comes with a major disadvantage, just like any other purely microscopic method: it only provides a partial view of the skin due to the low penetration depth.

29 Aug 2016

New research may explain why people with blood group O get more severely ill from cholera

People with blood type O often get more severely ill from cholera than people of other blood types. New research from Washington University School of Medicine in St. Louis may explain why.

29 Aug 2016

NEJM publishes MINDACT trial results

Agendia, Inc., a world leader in personalized medicine and molecular cancer diagnostics, announces the peer-reviewed publication of the primary outcome results of the Microarray In Node-negative and 1 to 3 positive lymph node Disease may Avoid ChemoTherapy (MINDACT) clinical trial in the prestigious New England Journal of Medicine (NEJM). (i, iii, iv) The publication demonstrates that 46% of breast cancer patients considered for chemotherapy, whose tumors are classified MammaPrint Low Risk, have excellent survival without chemotherapy, and can thus be candidates to avoid this toxic therapy.

29 Aug 2016

Interpace Diagnostics introduces new AccuCEA Insights for diagnosing and treating pancreatic cancer

Interpace Diagnostics Group, a company that provides clinically useful molecular diagnostic tests and pathology services for evaluating risk of cancer by leveraging the latest technology in personalized medicine for better patient diagnosis and management, reported today that the Company has launched a new version of their AccuCEA™ product called "Insights" for Gastroenterologists who focus on diagnosing and treating pancreatic cancer.

24 Aug 2016

New research discovers how opposite-sex hormonal therapy influences the brain

Women and men often show marked differences as regards mental illnesses. In order to learn more about this phenomenon, a project supported by the Austrian Science Fund FWF explored how opposite-sex hormonal therapy applied to transgender individuals influences the brain.

24 Aug 2016

Study examines psychological impact of tumor gene testing in subset of NCI-MATCH patients

The ECOG-ACRIN Cancer Research Group has received federal approval to add a quality-of-life research study, COMmunication and Education in Tumor Profiling (EAQ152) or 'COMET' to the NCI-MATCH (EAY131) trial, already underway.

19 Aug 2016

Precision Medicine News and Research

Researchers identify, validate three distinct molecular subtypes of prostate cancer

Skin phenotype of pediatric eczema opens door for personalized treatment of AD in infants

Precision medicine trial shows analysing person's DNA improves treatment options for cancer patients

MSK introduces unique program to expand, streamline patient access to high-quality cancer care

Scientists discover genomic alterations in pediatric relapsed ALL

Scientists use novel theranostics technique for early thromboembolism diagnosis and treatment

CHOP researchers exploit gene discovery in severe epilepsy to identify precision treatment

Leading cancer organizations publish new guidelines on postmastectomy radiotherapy

Researchers explain novel approach for analyzing diverse immune responses

Small implanted device can improve breast cancer survival by detecting cancer cells

Real-time MRI guidance could help target and deliver stem cell therapies

New molecular mechanism may explain pain relieving drug’s diverse benefits

Nanomechanical microcantilevers can quickly detect mutations in patients with malignant melanoma

Respiratory viral infection triggering asthma attack in children linked to treatment failure

Could a light-listening photonics device detect skin disease? An interview with Prof. Vasilis Ntziachristos

New research may explain why people with blood group O get more severely ill from cholera

NEJM publishes MINDACT trial results

Interpace Diagnostics introduces new AccuCEA Insights for diagnosing and treating pancreatic cancer

New research discovers how opposite-sex hormonal therapy influences the brain

Study examines psychological impact of tumor gene testing in subset of NCI-MATCH patients

Event guide: The 4th Precision Medicine in Inflammatory Bowel Disease Summit eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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