Genes News and Research

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Method for mass-producing embryonic stem cells

That's important because traditional laboratory methods used to grow these cells are costly and don't produce cells fast enough to respond to increasing demands for human embryonic stem cells, said Shang-Tian Yang, a professor of chemical and biomolecular engineering at Ohio State University.

16 Mar 2005

Diabetes Busting Burgers!

Chemists with the U.S. Department of Agriculture recently presented a preliminary report to the 229th national meeting of the American Chemical Society, in which they say they have discovered a form of soluble cellulose that, if added to high-fat food. The new finding could soon benefit people who regularly eat fast-foods that are high in fat.

16 Mar 2005

Aspirin use appears to reduce the incidence of colon polyps

The association between regular aspirin use and a reduced risk of precancerous colon polyps may be strongest in those with particular genetic variants.

15 Mar 2005

Discovery of key molecule that controls the growth, spread and survival of pancreatic cancer cells

Pancreatic cancer kills 30,000 Americans every year. Not only is there no cure, but there are no effective treatments. That may change if a new finding by Mayo Clinic researchers continues to show promise.

15 Mar 2005

Most comprehensive genome-wide experimental analyses of sense-antisense transcripts to date

A team of scientists led by Dr. Kuniya Abe from the RIKEN BioResource Center in Japan has performed one of the most comprehensive genome-wide experimental analyses of sense-antisense transcripts to date. Their findings are published in the April issue of the journal Genome Research.

15 Mar 2005

Doctors may soon be able to diagnose multiple sclerosis (MS) with a simple blood test

New research by Wake Forest University Baptist Medical Center and colleagues suggests that one day, doctors may be able to diagnose multiple sclerosis (MS) with a simple blood test. The findings are reported in the current issue of the Journal of Molecular Neuroscience.

15 Mar 2005

Gene therapy helps Lou Gehrig's disease

The most common form of motor neurone disease, called amyotrophic lateral sclerosis (ALS) or Lou Gehrig's disease, is caused when neurones in the spinal cord die, leading to muscle wasting and total paralysis.

14 Mar 2005

Ten more cases of human bird flu in Viet Nam

Full information is desperately needed to assess the risks of a pandemic that in a worst-case scenario could claim tens of millions of lives worldwide says the United Nations health agency.

14 Mar 2005

£800,000 to boost research into fighting viruses

A team of University of Glasgow scientists have received a grant of £800,000 from the Wellcome Trust to research a mechanism that blocks a critical step in the replication cycle of retroviruses. In the long term, the research could lead to the design of new therapeutic strategies or drugs against retroviruses, which cause diseases such as AIDS and certain leukemias.

14 Mar 2005

New biocentre which will revolutionise the way future medicines are produced

The University of Manchester has been awarded £6m to open a new biocentre which will revolutionise the way future medicines are produced – making them safer and more effective.

From The University of Manchester 14 Mar 2005

Genes play a substantial role in the development of age-related macular degeneration

Genes play a substantial role in the development of age-related macular degeneration (AMD), one of the leading causes of irreversible blindness among older individuals, according to an article in the March issue of Archives of Ophthalmology, one of the JAMA/Archives journals.

14 Mar 2005

New twist on the role that estrogens play in the development of behavioral differences between men and women

What makes a man behave like a man and a woman a woman? The answer may be partly in your genes. Researchers at the University of Virginia Health System have discovered a new twist on the role that estrogens play in the development of behavioral differences between males and females.

14 Mar 2005

High-dose radiation and bone marrow transfer treatments on glaucoma-susceptible mice completely blocked development of glaucoma

In a discovery that could point to new treatments for a wide range of neurodegenerative diseases, Jackson Laboratory researchers have found that high-dose radiation and bone marrow transfer treatments on glaucoma-susceptible mice completely blocked the development of glaucoma, by preventing neurodegeneration.

14 Mar 2005

Gene identified that confers susceptibility to age-related macular degeneration

By combining the tools of high-throughput biology and statistical genetics, scientists at Rockefeller University, Yale University School of Public Health and the National Eye Institute have identified a gene that confers susceptibility to age-related macular degeneration (AMD), the most common cause of vision loss in the United Sates for those over 60.

14 Mar 2005

New way of looking at MicroRNA and how it controls gene expression

A group of scientists at The Scripps Research Institute is reporting a discovery that sheds light on an area of research fundamental to everything from the normal processes that govern the everyday life of human cells to the aberrant mechanisms that underlie many diseases, including cancer and septic shock.

13 Mar 2005

Gene for AMD has now been identified by researchers

Age-related macular degeneration (AMD) is a debilitating eye disease affecting about 15 million people in the United States.

13 Mar 2005

Active brains stave off Alzheimer's signs

Mice who keep busy playing with toys also keep their brains and bodies active; more importantly, they also have lower levels of the peptides and brain plaques associated with Alzheimer's disease, compared to mice raised in environments not "enriched" with chew toys, running wheels,and tunnels, according to a new study in the 11 March issue of the journal Cell.

13 Mar 2005

Telomerase finding has major implications for cancer

UCLA biochemists have determined the three-dimensional structure of a major domain of telomerase, the enzyme that helps maintain telomeres - small pieces of DNA on the ends of chromosomes that act as protective caps - allowing DNA ends to be copied completely when cells are replicated.

9 Mar 2005

Overlapping signals in embryo help get the backbone right

A major step in the development of the vertebrate embryo - the establishment of a back that morphs into a brain, spinal cord and muscles - turns out to be so important that the body uses at least three signals to make sure it happens properly.

9 Mar 2005

Finding may open new horizons for understanding the initiation of chemically induced cancers

A team from the chemistry and biology departments of New York University, in collaboration with Memorial Sloan Kettering Cancer Center (MSKCC), has uncovered a conformational switch - a change in shape in a carcinogen-damaged DNA site - in tumor suppressor genes altered by a known cancer-causing chemical found in cigarette smoke.

9 Mar 2005