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Targeting enzyme responsible for glucose metabolism halts tumor growth, say researchers

Cancer cells generate energy differently than normal cells, a characteristic that helps them to survive and metastasize. A major goal in the field of cancer metabolism is to find ways to overcome this survival advantage.

11 Apr 2014

Scientists discover protein potentially good target for influenza A virus

Scientists at The University of Texas at Austin have discovered that a protein produced by the influenza A virus helps it outwit one of our body's natural defense mechanisms. That makes the protein a potentially good target for antiviral drugs directed against the influenza A virus.

11 Apr 2014

Study explores benefits of medication therapy management in Medicare patients

Low-risk Medicare patients entering home health care who received medication therapy management by phone were three times less likely to be hospitalized within the next two months, while those at greater risk saw no benefit, according to a study led by Purdue University.

11 Apr 2014

EU-funded project aims to find solution to combat hepatitis C epidemic in Egypt

New ways to differentiate between chronic and self-clearing infections may help towards effective patient management and reduce drug costs. But there are major challenges in implementation.

11 Apr 2014

Analysis of Medicare pay shows variations in drugs used and earnings by specialists

The Washington Post examines how drugs administered by doctors is different in various regions of the country. Other outlets look at other issues, including how eye doctors are among the highest paid specialty.

11 Apr 2014

Guidance on use of Tamiflu needs to be reviewed in light of most recent evidence

Tamiflu (the antiviral drug oseltamivir) shortens symptoms of influenza by half a day, but there is no good evidence to support claims that it reduces admissions to hospital or complications of influenza.

11 Apr 2014

Taking a close-to-home look at the Medicare billing data

Other news outlets offer localized takes on the Medicare data, including the Miami Herald's coverage of a physician who emerged as the federal program's top-paid doctor, the Philadelphia Inquirer's look at an ambulance business' billing patterns and the Seattle Times' examination of ophthalmologists.

11 Apr 2014

Researchers identify biological process that appears to trigger Parkinson's disease

Working with human neurons and fruit flies, researchers at Johns Hopkins have identified and then shut down a biological process that appears to trigger a particular form of Parkinson's disease present in a large number of patients. A report on the study, in the April 10 issue of the journal Cell, could lead to new treatments for this disorder.

11 Apr 2014

Researchers untangle genetic and environmental factors related to drug reactions

Why do people respond differently to the same drug? For the first time, researchers have untangled genetic and environmental factors related to drug reactions, bringing us a step closer to predicting how a drug will affect us.

11 Apr 2014

Rite Aid's fourth quarter revenues increase 2.2% to $6.6 billion

Rite Aid Corporation today reported operating results for its fourth quarter and fiscal year ended March 1, 2014.

10 Apr 2014

Assembly Pharmaceuticals, BioCrossroads develop novel drugs that have potential to treat chronic HBV infection

Assembly Pharmaceuticals and BioCrossroads today announced that the BioCrossroads Indiana Seed Fund II has made an investment in Assembly Pharmaceuticals. Assembly is developing novel drugs for the treatment and potential cure of chronic hepatitis B virus (HBV) infection.

10 Apr 2014

First Edition: April 10, 2014

Today's headlines include a range of stories taking additional looks at the Medicare physician payment data released yesterday by the Centers for Medicare & Medicaid Services.

10 Apr 2014

BioLineRx to initiate Phase 1/2 clinical trial on new drug candidate for CML treatment

BioLineRx, a clinical-stage biopharmaceutical company dedicated to identifying, in-licensing and developing promising therapeutic candidates, announced today that Prof. Arnon Nagler, Director of the Hematology Division and Bone Marrow Transplantation Center at Sheba Medical Center, Israel, has received final regulatory approval to evaluate BioLineRx's BL-8040 as a treatment for chronic myeloid leukemia (CML) in a Phase 1/2 clinical study.

10 Apr 2014

New discovery opens door to development of new treatments that stop progression of Parkinson's disease

A research led by the Research Institute Vall d'Hebron (VHIR), in which the University of Valencia participated, has shown that pathological forms of the α-synuclein protein present in deceased patients with Parkinson's disease are able to initiate and spread in mice and primates the neurodegenerative process that typifies this disease.

10 Apr 2014

Researchers find that cancer gene require copper to promote tumor growth

Drugs used to block copper absorption for a rare genetic condition may find an additional use as a treatment for certain types of cancer, researchers at Duke Medicine report.

10 Apr 2014

Mayo Clinic research shows RA patients more likely to develop chronic kidney disease

Rheumatoid arthritis patients are likelier than the average person to develop chronic kidney disease, and more severe inflammation in the first year of rheumatoid arthritis, corticosteroid use, high blood pressure and obesity are among the risk factors, new Mayo Clinic research shows.

10 Apr 2014

Dosage and schedules may improve effects of PI3K-inhibitors to target breast cancer tumors

Researchers from the Geisel School of Medicine at Dartmouth will present a scientific poster on Wednesday, April 9, 2014 at the American Association of Cancer Researchers conference in San Diego, CA.

10 Apr 2014

Studies provide evidence to clarify role of NAFLD as independent risk factor for development of CVD

Two new studies presented today at the International Liver CongressTM 2014 have provided more evidence to clarify the role of non-alcoholic fatty liver disease (NAFLD) as an independent risk factor for the development of cardiovascular disease (CVD).

10 Apr 2014

Small financial incentives can improve people’s completion of HBV vaccination, study finds

Small financial incentives, totalling as little as £30, can dramatically increase the likelihood of people who inject drugs completing a course of hepatitis B virus (HBV) vaccination, according to new research published in The Lancet.

10 Apr 2014

Study shows dabrafenib has no added benefit in comparison with dacarbazine

Dabrafenib (trade name: Tafinlar) has been approved since August 2013 for the treatment of advanced melanoma. In January 2014, in an early benefit assessment pursuant to the "Act on the Reform of the Market for Medicinal Products" (AMNOG), the German Institute for Quality and Efficiency in Health Care (IQWiG) had determined that dabrafenib has no added benefit in comparison with dacarbazine.

10 Apr 2014

Drugs News and Research

Targeting enzyme responsible for glucose metabolism halts tumor growth, say researchers

Scientists discover protein potentially good target for influenza A virus

Study explores benefits of medication therapy management in Medicare patients

EU-funded project aims to find solution to combat hepatitis C epidemic in Egypt

Analysis of Medicare pay shows variations in drugs used and earnings by specialists

Guidance on use of Tamiflu needs to be reviewed in light of most recent evidence

Taking a close-to-home look at the Medicare billing data

Researchers identify biological process that appears to trigger Parkinson's disease

Researchers untangle genetic and environmental factors related to drug reactions

Rite Aid's fourth quarter revenues increase 2.2% to $6.6 billion

Assembly Pharmaceuticals, BioCrossroads develop novel drugs that have potential to treat chronic HBV infection

First Edition: April 10, 2014

BioLineRx to initiate Phase 1/2 clinical trial on new drug candidate for CML treatment

New discovery opens door to development of new treatments that stop progression of Parkinson's disease

Researchers find that cancer gene require copper to promote tumor growth

Mayo Clinic research shows RA patients more likely to develop chronic kidney disease

Dosage and schedules may improve effects of PI3K-inhibitors to target breast cancer tumors

Studies provide evidence to clarify role of NAFLD as independent risk factor for development of CVD

Small financial incentives can improve people’s completion of HBV vaccination, study finds

Study shows dabrafenib has no added benefit in comparison with dacarbazine

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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