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Ocular oncologists link immunotherapy with potentially vision-robbing side effect

New immunotherapy treatments offer a remarkable chance for survival for patients with advanced melanoma and hard-to-treat cancers of the bladder, kidney and lung.

4 May 2018

Targeted 'click-to-release' chemotherapy leads to potent antitumor activity in mice

Antibody Drug Conjugates are relatively new anti-cancer drugs. They consist of an antibody to which a cell-killing molecule (chemotherapy) is attached. Antibodies can recognize and bind to certain receptors (the 'hands' on the outside of a cell) in a very targeted way.

4 May 2018

Scientists successfully test anti-alcoholism drug in animal models

Scientists at The University of Texas at Austin have successfully tested in animals a drug that, they say, may one day help block the withdrawal symptoms and cravings that incessantly coax people with alcoholism to drink.

4 May 2018

Genes that control the immune system may play role in hair graying

A study has found a link between genes that warn our bodies of a pathogenic infection and genes that play a role in determining hair color.

4 May 2018

Study shows how bacterial toxins can cripple normal cellular activity

Bacterial toxins can wreak mass havoc within cells by shutting down multiple essential functions at once, a new study has found.

4 May 2018

Researchers uncover new details on how the cerebellum predicts and learns from mistakes

In studies with monkeys, Johns Hopkins researchers report that they have uncovered significant new details about how the cerebellum -- the "learning machine" of the mammalian brain -- makes predictions and learns from its mistakes, helping us execute complex motor actions such as accurately shooting a basketball into a net or focusing your eyes on an object across the room.

4 May 2018

Researchers develop highly elastic biodegradable hydrogel for cell printing

Researchers at The University of Texas at Arlington have developed a highly elastic biodegradable hydrogel for bio-printing of materials that mimic natural human soft tissues.

4 May 2018

Astrocyte-targeted treatment may help alleviate symptoms of Alzheimer’s disease

A study by scientists of the German Center for Neurodegenerative Diseases points to a novel potential approach against Alzheimer's disease.

4 May 2018

Combining natural cures with biomedical devices improves bone health, growth

A WSU research team is bringing together natural medical cures with modern biomedical devices in hopes of bringing about better health outcomes for people with bone diseases.

4 May 2018

Researchers characterize new protein that plays key role in genetic stability of cells

Researchers from the Novo Nordisk Foundation Center for Protein Research at the Faculty of Health and Medical Sciences have characterized a new protein that is important to the genetic stability of our cells.

3 May 2018

Cancer Center at BIDMC announces launch of new Immunotherapy Institute

The Cancer Center at Beth Israel Deaconess Medical Center today announced the launch of a new clinical and research institute that will build on BIDMC's long history of leadership in immunotherapy and cell therapeutics.

3 May 2018

UIC scientists discover way to generate heart cells for research on causes of AFib

University of Illinois at Chicago researchers have discovered a way turn pluripotent stem cells into atrial cells, which make up the upper chambers, or atria, of the heart. The discovery will enable them to better study atrial fibrillation, the most common heart rhythm disorder also known as AFib, which originates in the heart's atria.

3 May 2018

COPD-related inflammation prevented in experimental model

Chronic obstructive pulmonary disease, or COPD for short, is believed to be the third most common cause of death worldwide. However, because the underlying mechanism is still largely unknown, today's treatments can only slow progression of the disease.

3 May 2018

New study evaluates expression of PD-L1 in human medulloblastoma

This study evaluated the expression of PD-L1 and markers of immune mediated resistance in human medulloblastoma, the most common malignant pediatric brain tumor.

3 May 2018

Study provides vital information to develop successful PI5P4K inhibitors for p53-mutant cancers

One major hallmark of cancer cells is their ability to adapt to stressful conditions such as nutrient deprivation. Rapidly growing tumor cells must compete for the ever-diminishing supply of nutrients in the surrounding environment to survive and proliferate. Targeting these adaptive mechanisms represents a promising approach for cancer therapeutics.

3 May 2018

Scientists discover mechanism behind unusual form of tissue regeneration in the liver

By studying a rare liver disease called Alagille syndrome, scientists from Cincinnati Children's and the University of California San Francisco (UCSF) have discovered the mechanism behind an unusual form of tissue regeneration that may someday reduce the need for expensive and difficult-to-obtain organ transplants.

3 May 2018

Xploro: Improving Child Health Literacy Through AI and AR

The way that sick children are taught about their condition is outdated and often doesn't cater to their needs. Dom Raban from Corporation Pop is hoping to change that, through the development of an app that uses artificial intelligence to answer any questions children may have about their care in real-time.

3 May 2018

Stem cells cultured in vitro self-assemble into embryo

An embryo has been created in vitro from mouse stem cells cultured with a 3D scaffold. The resulting structure was remarkably similar to a natural mouse embryo.

3 May 2018

Moving beyond traditional 'magic bullet' approach for discovering new drugs

It's time to move beyond the traditional 'magic bullet' approach for discovering new drugs and start leveraging the full complexity of Mother Nature, say Vanderbilt Professor of Chemistry Brian Bachmann and Assistant Professor of Cell and Developmental Biology Jonathan Irish.

3 May 2018