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Doctors cure sickle cell patients using allogeneic stem cells

Seven adults with sickle cell disease have been cured by doctors at the University of Illinois Hospital, thanks to the development of a new protocol for stem cell transplantation.

25 Apr 2018

Why are Antibiotics Overprescribed for Meningitis Treatment?

Meningitis is a relatively rare disease, with our estimates for the incidence of meningitis in the UK being about 3.2 cases of meningitis per 100,000 adults. Crucially, bacterial meningitis is linked to significant morbidity and mortality - up to 30% mortality in pneumococcal meningitis cases.

25 Apr 2018

Researchers uncover reason why exercise may be beneficial for the heart

Doctors, health organizations, and the Surgeon General all agree that exercise is good for the heart -- but the reasons why are still not well understood.

25 Apr 2018

Viruses can exploit a suprising weakness of brain cells to spark hydrocephalus

Viruses may spark hydrocephalus by exploiting a suprising weakness of cells that circulate fluid in the brain, says a new study by Duke University scientists.

25 Apr 2018

HBP researchers develop new tool to examine role of genes in disease-relevant brain regions

Elucidating the way from genes to cognition requires detailed insight into how anatomical areas with specific gene activities contribute to brain function and dysfunction. Up to now, the scientific community has developed many separate brain atlases for different modalities and scales.

25 Apr 2018

New combination therapy could improve survival in children with high-risk neuroblastoma

Investigators at the Children's Center for Cancer and Blood Diseases at Children's Hospital Los Angeles provide preclinical evidence that the presence of tumor-associated macrophages--a type of immune cell--can negatively affect the response to chemotherapy against neuroblastoma.

25 Apr 2018

Expression of long non-coding RNAs can result in high levels of specific proteins involved in cancer

A Danish-German research team has shown that not only the where and when of long non-coding RNA expression is important for their function but also the how.

25 Apr 2018

Key signaling protein in Huntington's disease found to have deleterious effects on heart function, shows study

Researchers investigating a key signaling protein in Huntington's disease describe deleterious effects on heart function, going beyond the disease's devastating neurological impact.

25 Apr 2018

Coastal Genomics' LightBench integrated with Hamilton liquid handler systems to bring efficiencies, savings for clinical laboratories

Hamilton Robotics is proud to integrate the LightBench with Ranger Technology from Coastal Genomics onto the NIMBUS® Select and all Hamilton liquid handling platforms. Together, they automate DNA protocols and enable fully automated electrophoresis for size selection or quality control. The combination brings efficiencies and savings for clinical laboratories of any size or budget.

From Hamilton Process Analytics 25 Apr 2018

Study explains how colon cancer cells spread to the liver

Colorectal cancer is the third most common cancer worldwide and the third-leading cause of cancer-related deaths. The main cause of death in patients with colorectal cancer is liver metastasis, with nearly 70% of patients eventually developing a liver tumor.

25 Apr 2018

Salk researchers develop new glioblastoma model using gene-edited organoids

Glioblastoma multiforme (GBM) is an incredibly deadly brain cancer and presents a serious black box challenge. It's virtually impossible to observe how these tumors operate in their natural environment and animal models don't always provide good answers.

25 Apr 2018

Experimental drug for rheumatoid arthritis prevents side effect of stem cell transplants

An investigational drug in clinical trials for rheumatoid arthritis prevents a common, life-threatening side effect of stem cell transplants, new research from Washington University School of Medicine in St. Louis shows.

25 Apr 2018

Bariatric surgery successes pave way for new type 2 diabetes treatment

Bariatric surgery has long yielded almost immediate health benefits for patients with type 2 diabetes, and new findings on the reasons for remission may be the key to developing drug alternatives to surgery.

25 Apr 2018

Preantral zinc deficiency may affect fertility months

An estimated 10 percent of couples in the U.S. struggle with infertility. While a variety of factors can make it difficult for some people to get pregnant, ovulation disorders are a leading cause of female infertility.

24 Apr 2018

Researchers identify novel pathway in development of AML with poor prognosis

Acute myeloid leukemia is a cancer of the blood and bone marrow that comprises 1% of all new cancer cases and almost 2% of cancer deaths in the U.S. The five-year survival rate for the disease is less than 20%.

24 Apr 2018

New technique harnesses 'natural barcodes' to facilitate better cell tracking

Each of us carries in our genomes about 10 million genetic variations called single nucleotide polymorphisms, which represent a difference of just one letter in the genetic code.

24 Apr 2018

Study highlights potential of stem cells derived from adults in regenerative medicine

Donor age does not appear to influence the functionality of stem cells derived from adult body tissues, concludes a new review. The analysis of research on induced pluripotent stem cells (iPSCs) finds that not only are typical signs of aging reversed in iPSCs, but cells derived from both older and younger donors show the same ability to differentiate into mature body cells.

24 Apr 2018

Researchers discover new gene associated with aortic aneurysms

An interdisciplinary team of researchers has identified a new gene linked to human aortic aneurysms. By combining comprehensive genetic studies in the fruit fly, dataset searches and analysis of diseased human aortic tissue, the researchers shed light on mechanisms not previously known to be associated with this devastating disease.

24 Apr 2018

Studies provide advanced knowledge about renal cancer

Cell, the most prestigious international journal in the field of biology, is today publishing a set of three papers on renal cancer. Among the authors of these papers is Dr José Ignacio López, head of the Pathological Anatomy Service of University Hospital Cruces and tenured lecturer in Pathological Anatomy at the UPV/EHU's Faculty of Medicine and Nursing.

24 Apr 2018

Researchers discover key link between fat, immune cells and heat regulation

Scientists have just made a surprising discovery involving fat and special immune cells that live within it -- it turns out that 'gd T cells' are the key cogs in the biological wheel that regulates our body heat and protects us against cold shock.

24 Apr 2018