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UC San Diego Health offers new bladder-saving gene therapy to treat localized bladder cancer

UC San Diego Health is the first health system in San Diego County to offer a new bladder-saving gene therapy to treat localized bladder cancer.

8 Jul 2024

Long-term effects of chemotherapy on hearing and quality of life in testicular cancer survivors

An interdisciplinary study led by researchers at the University of South Florida and Indiana University has uncovered significant findings on the long-term effects of one of the most common forms of chemotherapy on cancer survivors.

28 Jun 2024

Study uncovers role of Y chromosome loss in transthyretin cardiac amyloidosis

Researchers at Boston Medical Center (BMC) and Boston University (BU) Chobanian & Avedisian School of Medicine, in collaboration with an international team of scientists, shared findings from a new study published in the American Heart Association journal, Circulation: Heart Failure that explores a common cause of heart disease in older men called transthyretin cardiac amyloidosis (ATTR-CA).

27 Jun 2024

Noninvasive urine test enhances early detection of bladder cancer in patients with hematuria

One of the first signs of bladder cancer can be blood in the urine (hematuria). Investigators developed and analyzed the results of a streamlined and simplified DNA-based urine test to improve the accuracy of early detection of bladder cancer in patients with hematuria.

20 Jun 2024

Less healthy intestinal flora could increase the risk of serious infection

The composition of the intestinal flora can predict the chances of developing serious infections such as pneumonia.

20 Jun 2024

Unlocking the role of B cells in neuromyelitis optica spectrum disorder treatment

Autoimmune diseases cannot currently be cured, only treated, and this is also true for neuromyelitis optica spectrum disorder, which affects the central nervous system.

19 Jun 2024

Study identifies drug target to prevent autonomic dysfunction after spinal cord injury

In response to stressful or dangerous stimuli, nerve cells in the spinal cord activate involuntary, autonomic reflexes often referred to as "fight or flight" responses.

12 Jun 2024

First-in-human trial shows safety and efficacy of CAR T cell therapy for advanced prostate cancer

Treating prostate cancer with immunotherapy is currently difficult to do. But results from a first in-human phase 1 trial using a chimeric antigen receptor (CAR) T cell therapy developed by researchers from City of Hope, one of the largest cancer research and treatment organizations in the United States, showed that patients with advanced prostate cancer can be treated safely with the cellular immunotherapy with promising therapeutic activity, according to the phase 1 trial study published today in Nature Medicine.

12 Jun 2024

Next-generation soft robots with sensory e-skin enhance patient care

University of North Carolina at Chapel Hill scientists have created innovative soft robots equipped with electronic skins and artificial muscles, allowing them to sense their surroundings and adapt their movements in real-time, according to the paper, "Skin-Inspired, Sensory Robots for Electronic Implants," in Nature Communications.

11 Jun 2024

Unveiling Pseudomonas aeruginosa's lung invasion tactics with human lung microtissues

How do pathogens invade the lungs? Using human lung microtissues, a team at the Biozentrum of the University of Basel has uncovered the strategy used by a dangerous pathogen.

10 Jun 2024

New hope for BCG-unresponsive bladder cancer patients with innovative combination therapy

In a groundbreaking advance that could revolutionize bladder cancer treatment, a novel combination of cretostimogene grenadenorepvec and pembrolizumab has shown remarkable efficacy in patients with Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle invasive bladder cancer.

6 Jun 2024

New approach reduces the required drug dosage for cancer treatment

Traditional chemotherapy often poses significant challenges, including severe side effects, damage to healthy tissue and limited efficacy.

6 Jun 2024

Type 2 diabetes linked to higher cancer risk, especially with diabetic retinopathy, study finds

A recent study in BMC Medicine found that type 2 diabetes significantly increases the risk of various cancers, with the risk being even higher in patients with diabetic retinopathy (DR).

2 Jun 2024

COVID-19 associated with higher risk of erectile dysfunction

Men previously diagnosed with COVID-19 are at a greater risk of developing new-onset erectile dysfunction.

31 May 2024

Notre Dame study identifies high-risk population for CAUTIs due to fibrinolytic deficiencies

Urinary catheters are required for nearly every surgical procedure. However, a major challenge for the health care industry is predicting who may develop catheter-associated urinary tract infections (CAUTIs) and when these infections may lead to death.

30 May 2024

Understanding the long-term effects and safety of testosterone therapy in transgender men

Transgender individuals often face unique challenges in aligning their physical bodies with their true gender identity.

30 May 2024

Study links higher microplastic levels in urine to endometriosis risk

A study in Ecotoxicology and Environmental Safety finds higher levels of microplastics in urine samples from endometriosis patients compared to healthy individuals.

21 May 2024

Novel therapy reprograms immune cells, shrinks prostate and bladder cancers in animal study

A novel therapy that reprograms immune cells to promote antitumor activity helped shrink hard-to-treat prostate and bladder cancers in mice, according to research from the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy and Johns Hopkins Drug Discovery.

21 May 2024

Study reveals no survival benefit from systemic therapy in very advanced solid tumors

Patients with very advanced solid tumors saw no significant improvement in overall survival after receiving systemic therapy, according to a study published today in JAMA Oncology by researchers at The University of Texas MD Anderson Cancer Center and Yale Cancer Center.

17 May 2024

Expanding treatment horizons for hypermutated urothelial carcinomas beyond immunotherapy

A new editorial paper was published in Oncoscience (Volume 11) on April 25, 2024, entitled, "Therapeutic opportunities for hypermutated urothelial carcinomas beyond immunotherapy."

10 May 2024