CAR T cell News and Research

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Phase 2 clinical trial of CAR T-cell therapy starts at Atlantic Health System

Atlantic Health System is treating patients in a new Phase 2 clinical trial of CAR T-cell therapy at Morristown Medical Center. A select number of sites across the U.S. are involved in this study, which is done on an outpatient basis.

25 Oct 2019

ConvertibleCAR immunotherapy can be used to attack HIV latent reservoir

A team of Gladstone scientists and their partners at Xyphos Biosciences, Inc. describe a new way of attacking cells infected by HIV in this week's issue of the journal Cell.

24 Oct 2019

Scientists harness the power of immune system to test novel cancer treatment

The field of immunotherapy has revolutionized the way people with incurable cancers are treated, saving the lives of many people whose disease would have otherwise been seen as a death sentence. Despite its success in treating people with deadly forms of leukemia and lymphoma, there are still many people who do not benefit from the treatment or eventually experience a relapse of their cancer.

16 Oct 2019

Drug-light combination could offer better control over CAR T-cell treatments

Bioengineers at the University of California San Diego are a step closer to making CAR T-cell therapy safer, more precise and easy to control.

15 Oct 2019

NUS researcher invents novel transfection technique to deliver DNA into immune cells

Immunotherapy is a promising cancer treatment that uses genetically modified immune cells to fight cancer. It can be used as a primary treatment or in combination with other treatments such as radiation and chemotherapy to slow down or stop the growth of cancer cells and prevent them from spreading to other parts of the body.

4 Oct 2019

CAR T-cell therapy may be effective in killing solid tumor cells

There is now a multitude of therapies to treat cancer, from chemotherapy and radiation to immunotherapy and small molecule inhibitors. Chemotherapy is still the most widely used cancer treatment, but chemotherapy attacks all the rapidly dividing cells that it locates within the body, whether they're ultimately harmful or beneficial.

2 Oct 2019

Cancer Research Institute declares 2019 recipients of top scientific and philanthropic awards

The Cancer Research Institute (CRI), a nonprofit organization dedicated to advancing the discovery and development of powerful immunotherapies for all forms of cancer, has announced the 2019 recipients of its highest scientific and philanthropic awards.

27 Sep 2019

Scientists use CAR-T cells to reverse cardiac fibrosis

Scientists have used CAR-T cell therapy to treat cardiac fibrosis, a key part of heart disease and cardiac arrest.

12 Sep 2019

CAR T-cell therapy may be viable treatment option for heart disease

CAR T-cell therapy, a rapidly emerging form of immunotherapy using patients' own cells to treat certain types of cancers, may be a viable treatment option for another life-threatening condition: heart disease.

12 Sep 2019

Super-powered immune cells to attack tumors

Ground-breaking immune therapy promises to deliver vital evidence in the fight against cancer as researchers from the Centre for Cancer Biology open a new clinical trial using genetically engineered immune cells to treat solid cancers.

23 Aug 2019

New circulating immune cell could help predict type 1 diabetes risk

A new Finnish study suggests that type 1 diabetes may in part be caused by a novel subset of immune cells. This is because these cells, called peripheral T helper cells, are found to circulate at a higher rate in children with type 1 diabetes of recent onset, as well as in healthy children who later develop the condition.

20 Aug 2019

ISCT expresses concern about companies offering unproven T-cell preservation services

ISCT, the International Society for Cell and Gene Therapy, the global professional society of clinicians, researchers, regulatory specialists, technologists and industry partners in the cell and gene therapy sector, today announces its objection to linking the benefits of cellular immunotherapy, in particular Chimeric Antigen Receptor (CAR) T-cell therapy, with recent market offerings for third party cryopreserving and banking of T-cells for future therapeutic use.

8 Aug 2019

Research seeks to fight organ rejection in kidney transplant patients

While waiting on the transplant list, most patients are extremely sick and fighting just to stay alive.

1 Aug 2019

CAR-T cells used to target glioblastoma

Immunotherapy is the new weapon against cancers and building upon existing research, a team of researchers from the Massachusetts General Hospital have devised a way to make immunotherapy more effective in a deadly and common form of brain cancer called glioblastoma.

24 Jul 2019

New study reveals 'clutch' proteins responsible for putting T cell activation 'into gear'

In collaborative research, scientists from three continents were able to discover a crucial bit of information about how T cells move proteins inside them to drive the immune response. This could help evolve specific new treatments centered on T cell selectivity.

12 Jul 2019