Cardiomyopathy News and Research

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Cardiomyopathy is a group of diseases with primary, usually diffuse, involvement of the myocardium. The myocardial disease is not secondary to ischaemic, valvular, congenital or pericardial disease.

Study provides new insight into the cellular and molecular biology of human heart failure

Studying heart samples from patients with cardiomyopathies, as well as from controls without heart disease, researchers have provided new insights into the cellular and molecular biology of human heart failure – a highly fatal condition that affects 23 million people worldwide.

5 Aug 2022

Individual genetic defects lead to heart failure in different ways, consortium reports

Cardiomyopathy is not a uniform disease. Rather, individual genetic defects lead to heart failure in different ways, an international consortium reports in Science.

4 Aug 2022

New study uncovers a likely proteome signature for reductive stress cardiomyopathy

Two years ago, University of Alabama at Birmingham researchers and colleagues reported that reductive stress - an imbalance in the normal oxidation/reduction, or redox, homeostasis - caused pathological changes associated with heart failure in a mouse model.

3 Aug 2022

Ultra-precise gene therapy technologies could edit or silence faulty genes causing fatal heart diseases

An injectable cure for inherited heart muscle conditions that can kill young people in the prime of their lives could be available within a few years, after an international team of researchers were announced as the winners of the British Heart Foundation's Big Beat Challenge.

29 Jul 2022

UK study finds an increase in cardiovascular diseases and diabetes up to 12 months after COVID-19

Researchers determined whether the incidence of new diabetes mellitus (DM) and cardiovascular diseases (CVDs) increases in a year among those recovering from COVID-19.

21 Jul 2022

Revolutionary technology identifies molecular alterations in failing hearts at single-cell resolution

Imagine, if scientists had a map of the heart, so granular in its accuracy that it even profiled details of the heart at the cellular level.

8 Jul 2022

Bereavement linked to increased risk of death in heart failure patients

Heart failure patients experiencing grief or in mourning following the loss of a close family member are at an increased risk of death, particularly during the first week following the family member's death, according to a study published today in JACC: Heart Failure.

6 Jul 2022

Pregnant women with PCOS have higher risk for heart problems during delivery

A common hormone disorder among women of reproductive age has been linked to an increased risk of adverse cardiovascular events and pregnancy outcomes at the time of birth, according to a new study led by Johns Hopkins Medicine researchers.

16 Jun 2022

New findings reveal potential mechanisms for cellular defects in human laminopathies

A Northwestern Medicine study has uncovered distinct roles for major nuclear lamin isoforms in maintaining intracellular interactions and cellular mechanics, according to findings published in the Proceedings of the National Academy of Sciences.

1 Jun 2022

Scientists determine trajectory and pathophysiology of post-COVID-19 syndrome

A new study utilizes multisystem imaging, along with biomarker analysis, to better understand the pathogenesis of COVID-19.

30 May 2022

Study unveils the novel driver of cardiomyocyte loss

Researchers from the group of Eva van Rooij used advanced sequencing technology to better understand the heart disease arrhythmogenic cardiomyopathy, in which heart muscle tissue is replaced by fat cells. Using explanted human hearts, they found regions in which heart muscle was actively degenerated and identified a new gene, ZBTB11, that drives heart muscle cell degradation. The results were published in Cardiovascular Research on 17 May 2022.

25 May 2022

Even safe levels of alcohol consumption may harm the heart

Levels of alcohol consumption currently considered safe by some countries are linked with development of heart failure, according to research presented at Heart Failure 2022, a scientific congress of the European Society of Cardiology.

22 May 2022

Unmarried heart failure patients lack confidence to manage their condition, study says

Unmarried heart failure patients appear less confident in managing their condition and more socially limited compared to their married counterparts, according to research presented today at Heart Failure 2022, a scientific congress of the European Society of Cardiology.

22 May 2022

Benefits of endurance exercise in primary mitochondrial disease depend on the underlying mutation

Mitochondria serve as the main source of energy production in our cells, and endurance exercise is generally known to improve the function of mitochondria.

4 May 2022

High-performing age-stratified machine-learning models for the prediction of the severity of COVID-19 progression

The current study aims to use sophisticated machine learning models that stratify patient data by age group to predict disease progression in almost 7,000 patients studied in community hospital settings.

4 May 2022

$6 million grant to fund research investigating the role of immune system in heart failure

A new grant for researchers at Washington University School of Medicine in St. Louis will fund research investigating the role of the immune system in heart failure. Finding ways to harness beneficial immune cells could lead to new therapies that encourage the heart to heal after injuries.

2 May 2022

Cardiomyopathy News and Research

Further Reading

Study provides new insight into the cellular and molecular biology of human heart failure

Individual genetic defects lead to heart failure in different ways, consortium reports

New study uncovers a likely proteome signature for reductive stress cardiomyopathy

Ultra-precise gene therapy technologies could edit or silence faulty genes causing fatal heart diseases

UK study finds an increase in cardiovascular diseases and diabetes up to 12 months after COVID-19

Revolutionary technology identifies molecular alterations in failing hearts at single-cell resolution

Bereavement linked to increased risk of death in heart failure patients

Pregnant women with PCOS have higher risk for heart problems during delivery

New findings reveal potential mechanisms for cellular defects in human laminopathies

Scientists determine trajectory and pathophysiology of post-COVID-19 syndrome

Study unveils the novel driver of cardiomyocyte loss

Even safe levels of alcohol consumption may harm the heart

Unmarried heart failure patients lack confidence to manage their condition, study says

Benefits of endurance exercise in primary mitochondrial disease depend on the underlying mutation

High-performing age-stratified machine-learning models for the prediction of the severity of COVID-19 progression

$6 million grant to fund research investigating the role of immune system in heart failure

How diet and nutrition impacts lifespan

New study predicts which hospitalized COVID-19 patients are at high risk for severe disease

Novel plug-and-play multi-organ chip can be customized to the patient

Researchers uncover a key regulator of pregnancy-associated heart growth

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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