Cell Metabolism News and Research

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Repressing a protein that facilitates DNA repair to potentiate chemotherapy

Chemotherapy kills tumor cells by causing damage to them. One of the most effective ways of causing damage is to prevent the two DNA strands from separating so that the cellular machinery cannot read the instructions written in the genes.

15 Jun 2021

Study elucidates how Omega-3 fatty acids poison tumor cells

So-called "good fatty acids" are essential for human health and much sought after by those who try to eat healthily. Among the Omega-3 fatty acids, DHA or docosahexaenoic acid is crucial to brain function, vision and the regulation of inflammatory phenomena.

11 Jun 2021

Discovery suggests new pathways for safeguarding the immune system’s ability to fight cancer

In order for cancer to grow and spread, it has to evade detection by our immune cells, particularly specialized "killer" T cells.

10 Jun 2021

ONK Therapeutics and Trinity researchers seek to improve cellular therapies for treating cancer

ONK Therapeutics Ltd, an innovative natural killer (NK) cell therapy company, today announced that it has been awarded an Innovation Partnership Programme grant by Enterprise Ireland (EI) to fund collaborative research at Trinity College Dublin, Ireland, led by Dr. David Finlay to optimize the metabolism and engineering of NK cells for improved cancer therapies.

8 Jun 2021

New chip mimicking bovine endometrium could play key role in cattle’s pregnancy success

To investigate factors that can jeopardize pregnancy success in cattle, researchers at the University of São Paulo (USP) in Brazil used a kind of chip to mimic the environment of the endometrium, the tissue that lines the inside of the uterus.

8 Jun 2021

Study confirms the importance of low-protein, high-carbohydrate diet

Researchers at the University of Sydney's Charles Perkins Centre conducted the largest ever study of nutrient interactions by examining the health of mice on 33 different diets containing various combinations of protein to carbs, and different sources of carbohydrate.

8 Jun 2021

Study explores therapeutic potential of exploiting autophagy cascade against COVID-19

Researchers recently reviewed current knowledge on links between autophagy and coronaviruses and how this knowledge can be used to repurpose autophagy modulators as potential treatment options for COVID-19. The review is published in the journal Frontiers in Microbiology.

7 Jun 2021

Gut-brain communication by distinct nerve cells differently controls satiety and blood sugar levels

The gut and the brain communicate with each other in order to adapt satiety and blood sugar levels during food consumption.

2 Jun 2021

Targeting mTOR pathway can improve the effectiveness of chemotherapies for pediatric brain cancer

Two experimental drug approaches that target vulnerabilities in cancer cell metabolism may extend survival and enhance the effectiveness of standard chemotherapies for a highly aggressive type of pediatric brain cancer.

21 May 2021

A potential treatment to prevent obesity-related liver damage

One of the especially dangerous health risks of being extremely overweight occurs when an obese person begins to accumulate fat in their liver.

18 May 2021

Sepsis can cause alterations in the functioning of defense cells that lead to death

An article published in Frontiers in Immunology suggests that sepsis can cause alterations in the functioning of defense cells that persist even after the patient is discharged from hospital.

12 May 2021

Sepsis can cause alterations in the functioning of defense cells that lead to death

An article published in Frontiers in Immunology suggests that sepsis can cause alterations in the functioning of defense cells that persist even after the patient is discharged from hospital.

12 May 2021

Could in vitro glycoengineering help produce better SARS-CoV-2 spike candidates for vaccine research?

A vexing problem in the development of vaccines has been the need to achieve the right glycosylation profile for the viral antigens. A new study, recently released as a preprint on the bioRxiv* server, shows how a sequential cell-free approach produced complex N-glycans from simpler types, in a one-pot reaction.

4 May 2021

New medical publication offers guidelines on how to manage patients with unexplained low blood sugar

A collaboration between experts and a Danish-based, global reaching patient organization has resulted in a groundbreaking medical publication, where guidelines are being presented on how to manage patients with unexplained low blood sugar.

30 Apr 2021

Modified immune cells may prove a game-changer for patients with late-stage cancers

Modified immune cells that ruthlessly kill cancerous tumors may prove a game-changer for people living with late-stage cancer.

15 Apr 2021

Chemical modification of RNA appears to play a critical role in inherited kidney disorder

A chemical modification of RNA that can be influenced by diet appears to play a key role in polycystic kidney disease, an inherited disorder that is the fourth leading cause of kidney failure in the U.S., UT Southwestern researchers report in a new study.

13 Apr 2021

$10.8 million grant from NIH helps establish Arkansas Integrative Metabolic Research Center

A $10.8 million grant from the National Institutes of Health will enable an interdisciplinary team of researchers at the University of Arkansas and University of Arkansas for Medical Sciences to address the role of cell and tissue metabolism in rare and common diseases such as cancer, diabetes, obesity and mitochondrial disorders.

6 Apr 2021

HCAs are a promising risk indicator of type 2 diabetes

A series of studies led by researchers from Hong Kong Baptist University have revealed that hyocholic acid and its derivatives (collectively known as HCAs), a component of bile acids that facilitate fat digestion, are a promising risk indicator of type 2 diabetes.

1 Apr 2021

Researchers reveal novel therapeutic target in the treatment of certain cancers

Mount Sinai Researchers Find "Removal of AKAP11 Protein by Autophagy as a key to Fuel Mitochondrial Metabolism and Tumor Cell Growth through activating protein kinase A (PKA) (Patent pending)"

1 Apr 2021

Study reveals how exercise during pregnancy confers metabolic health benefits in offspring

A mechanism has been identified that explains how physical exercise in pregnancy confers metabolic health benefits in offspring.

30 Mar 2021

Cell Metabolism News and Research

Repressing a protein that facilitates DNA repair to potentiate chemotherapy

Study elucidates how Omega-3 fatty acids poison tumor cells

Discovery suggests new pathways for safeguarding the immune system’s ability to fight cancer

ONK Therapeutics and Trinity researchers seek to improve cellular therapies for treating cancer

New chip mimicking bovine endometrium could play key role in cattle’s pregnancy success

Study confirms the importance of low-protein, high-carbohydrate diet

Study explores therapeutic potential of exploiting autophagy cascade against COVID-19

Gut-brain communication by distinct nerve cells differently controls satiety and blood sugar levels

Targeting mTOR pathway can improve the effectiveness of chemotherapies for pediatric brain cancer

A potential treatment to prevent obesity-related liver damage

Sepsis can cause alterations in the functioning of defense cells that lead to death

Sepsis can cause alterations in the functioning of defense cells that lead to death

Could in vitro glycoengineering help produce better SARS-CoV-2 spike candidates for vaccine research?

New medical publication offers guidelines on how to manage patients with unexplained low blood sugar

Modified immune cells may prove a game-changer for patients with late-stage cancers

Chemical modification of RNA appears to play a critical role in inherited kidney disorder

$10.8 million grant from NIH helps establish Arkansas Integrative Metabolic Research Center

HCAs are a promising risk indicator of type 2 diabetes

Researchers reveal novel therapeutic target in the treatment of certain cancers

Study reveals how exercise during pregnancy confers metabolic health benefits in offspring

Event Guide: 3rd Annual TRP Supply Chain & Manufacturing Summit eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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