Chromosomal Crossover News and Research

RSS

Tonix completes TNX-102 pharmacokinetic study on fibromyalgia syndrome

Tonix Pharmaceuticals Holding Corp., a specialty pharmaceutical company developing therapies for challenging disorders of the central nervous system completed a pharmacokinetic (PK) study of the first formulation of its lead drug, TNX-102, for the treatment of fibromyalgia syndrome.

6 Apr 2012

Green Coffee beans - the new weight loss formula

Green coffee beans could be the newest weight-loss fad as a new study finds that the bean extract may help people lose weight. When roasted at 475 degrees, coffee beans are sometimes described as rich and full-bodied. Before that they are termed green.

29 Mar 2012

NCCN issues first ever clinical practice guidelines for ALL

The National Comprehensive Cancer Network has issued its first ever NCCN Clinical Practice Guidelines in Oncology for Acute Lymphoblastic Leukemia.

21 Mar 2012

Contraception, abortion issues crop up in state legislatures, political races

The debate over the birth control mandate is seeping into West Virginia's governor race as reproductive-rights supporters assess their place amid losses in state legislatures.

9 Mar 2012

Ruxolitinib boosts QOL and survival for patients with myelofibrosis

A drug that relieves the severe symptoms of a life-threatening bone marrow cancer called myelofibrosis also improves the survival of patients with the disease, according to a phase III clinical trial published in the March 1 edition of New England Journal of Medicine.

1 Mar 2012

UVA, Johns Hopkins receive NIH grant to develop methods against glioblastoma

The most common primary brain cancer is glioblastoma, a highly aggressive and deadly form of tumor that kills about 95 percent of its victims within five years of diagnosis. Like other brain cancers, it is extremely difficult to treat because glioblastomas are usually deeply embedded within healthy brain tissue and therefore nearly impossible to safely access. Chemotherapy drugs cannot reach these tumors because a membrane between the bloodstream and brain tissue, called the blood-brain barrier, blocks them.

29 Feb 2012

RAD51 gene behind the cause of congenital mirror movements

Further work carried out on mice suggests that this gene plays a part in motor network cross-over. Cross-over is a key factor in the transmission of brain signals, because it allows the right side of the brain to control the left side of the body and vice versa. This research has been published in The American Journal of Human Genetics.

18 Feb 2012

Two prefrontal cortex areas critical in distinguishing emotions from facial expressions

It's Valentine's Day, he forgot to bring flowers, and somehow that painfully sad look on her face is simply not registering in his mind. Could be it's a problem in his prefrontal cortex? Neuropsychology researchers at the Montreal Neurological Institute and Hospital - The Neuro, McGill University, have found that two areas of the prefrontal cortex (PFC) are critical for either detecting or distinguishing emotions from facial expressions.

14 Feb 2012

Automated insulin pump delivery can reduce hypoglycemia in individuals with type 1 diabetes

An automated on/off feature built into insulin pump systems can suspend insulin delivery when it detects low blood glucose levels (via continuous glucose monitoring), significantly reducing the severity and duration of hypoglycemia in individuals with type 1 diabetes, according to a study published in Diabetes Technology & Therapeutics, a peer-reviewed journal from Mary Ann Liebert, Inc.

10 Feb 2012

Patients with degenerative spondylolisthesis do not benefit from epidural steroid injections

Researchers at the Rothman Institute at Jefferson examined data on patients being treated for lumbar stenosis and the degenerative spine condition spondylolisthesis and found that patients who received epidural steroid injections (ESI) had a higher rate of crossover to surgery and fared worse in physical health and bodily pain versus those who did not receive ESI, dispelling their pre-study hypothesis.

8 Feb 2012

Aggrenox not affected by co-administration of omeprazole: Study

Boehringer Ingelheim presented results of a drug interaction study that found Aggrenox (aspirin/extended-release dipyridamole), an antiplatelet medication, is not affected by the co-administration of omeprazole, a proton pump inhibitor (PPI), frequently used to treat several gastrointestinal conditions. These data were presented at the International Stroke Conference (ISC) in New Orleans.

3 Feb 2012

ESC welcomes 'intriguing' study on heart failure

The European Society of Cardiology (ESC) welcomes an "intriguing" study, published today in the Journal of the American College of Cardiology, featuring a completely novel approach for improving endothelial function in heart failure.

31 Jan 2012

Red wine could play a role in lowering risk of breast cancer

Aromatase inhibitors (AIs) prevent the conversion of androgens to estrogens, and could play a role in the development of breast cancer. This study of 36 pre-menopausal women consisted of a cross-over intervention trial to determine if there were differences between red wine and white wine in their effects on AIs.

20 Jan 2012

Antimicrobial impregnated scrubs effective in reducing MRSA

The use of antimicrobial impregnated scrubs combined with good hand hygiene is effective in reducing the burden of Methicillin-Resistant Staphylococcus Aureus (MRSA) on healthcare workers' apparel and may potentially play a role in decreasing the risk of MRSA transmission to patients, according to a new study from Virginia Commonwealth University researchers.

20 Jan 2012

Ethanol, nonalcoholic compounds in red wine may reduce risk of vascular disease

Observational epidemiologic studies relating wine and alcohol to health all suffer from the fact that they, of necessity, compare people who prefer certain beverages, but not the beverages themselves. While there have been many intervention trials in animals, randomized trials in humans are less common. Randomized crossover trials, in which each subject receives all interventions in sequence, can be especially important as they tend to avoid baseline differences among subjects and can detect effects of different interventions with smaller numbers of subjects.

18 Jan 2012

Magellan launches two fitness products

Magellan GPS announced today the launch of its first two products in its new fitness line: Switch and Switch Up. Designed to meet the needs of runners, cyclists, and multisport athletes, the new Switch Series is a powerful, adaptable, and customizable family of crossover GPS watches that will integrate seamlessly with third party sites.

7 Jan 2012

Avastin fails to live up to expectations for extending survival in ovarian cancer

Cancer drug Avastin has been found to add about four months to the time it takes for the cancer to worsen for women with advanced cases of ovarian cancer says a new report. However it may not extend survival significantly.

29 Dec 2011

Beef can play a role in a cholesterol-lowering diet

A new study published in the January 2012 edition of American Journal of Clinical Nutrition shows that beef can play a role in a cholesterol-lowering diet, despite commonly held beliefs.

16 Dec 2011

Dust storms have adverse effect on hospital EDs for COPD

A new study published in the journal Respirology reveals that dust storms have an adverse effect on emergency hospital admission for chronic lung disease, often known as chronic obstructive pulmonary disease.

6 Dec 2011

Preliminary top-line results from XenoPort's XP21279 Phase 2 trial for advanced Parkinson’s disease

XenoPort, Inc. announced today preliminary top-line results of a Phase 2, randomized, crossover clinical trial that compared optimized treatment with either Sinemet (immediate-release levodopa/carbidopa) or XP21279 co-formulated with carbidopa (279/CD) in advanced Parkinson's disease patients with motor fluctuations.

5 Dec 2011