Helicobacter pylori News and Research

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JAMA study shows decline in incidence of gastric cancer for all age groups

The incidence of a certain type of gastric cancer has declined in the last 30 years for all age groups and races, except for whites 25 to 39 years of age, according to a study in the May 5 issue of JAMA.

5 May 2010

New research shows link between infection-related diseases and risk of cancer

New research is emerging that suggests a link between infection-related diseases and risk of cancer, according to findings presented here at the American Association for Cancer Research 101st Annual Meeting 2010.

20 Apr 2010

Link between IL-8, MIF gene polymorphisms and progression of atrophic gastritis and intestinal metaplasia

Atrophic gastritis and intestinal metaplasia are two important precursory lesions in the process of intestinal type gastric cancer. However, the precise mechanism of the progression of these two lesions is still unclear, a few studies have investigated the risk of host gene polymorphism on the atrophic gastritis and intestinal metaplasia, but all of them are limited by their one-time point screen.

13 Apr 2010

Antibiotics lower risk of developing gastric cancer

Helicobacter pylori, a bacterium found in about 50% of humans worldwide, can cause stomach ulcers and, in extreme cases, gastric cancer. In an article for F1000 Medicine Reports, Seiji Shiota and Yoshio Yamaoka discuss the possible eradication of H. pylori infections

12 Mar 2010

Beneficial Alzheimer's therapies, update on prevention efforts focused at ADI International Conference

Beneficial Alzheimer's therapies that don't use drugs, and an update on prevention efforts, are the focus of the second day's plenary sessions at the 25th International Conference of Alzheimer's Disease International, March 12, 2010 at the Grand Hotel Palace, Thessaloniki, Greece.

4 Mar 2010

Breastfeeding and better hygiene may protect against peptic ulcer bacterium infection

Young children in developing countries are infected at an early age with the bacterium Helicobacter pylori, which can cause peptic ulcers and stomach cancer. New findings show that childrens´ immune responses help in fighting the bacteria. In addition, breastfeeding and better hygiene appear to protect against infection. The results provide hope for a vaccine, according to research from the Sahlgrenska Academy at the University of Gothenburg, Sweden.

1 Mar 2010

Pathogen study could provide new insights on gene regulation

About 50 percent of the world's population carry Helicobacter pylori (H. pylori) in their gastrointestinal tract - 30 percent of the German population are infected. Besides cancer, these bacteria are linked to other chronic diseases such as cardiovascular disease.

24 Feb 2010

Proteins found in intestines can recognize and kill bacteria that have human blood type molecules

A set of proteins found in our intestines can recognize and kill bacteria that have human blood type molecules on their surfaces, scientists at Emory University School of Medicine have discovered.

15 Feb 2010

Insight into mechanism H. pylori uses to evade the immune system

Helicobacter pylori (H. pylori) is the causal agent of chronic gastritis, ulcer and gastric cancer. It has the potential to persist in the human stomach for decades, sometimes causing neither harm nor clinical symptoms. Nevertheless, on some occasions, depending on the host immune system and the strain causing the infection, the outcome can be very serious. To maintain the infection, the bacterium must adapt to survive the host defences. One way to accomplish this is to sequentially change the external proteins on the bacterial surface.

10 Feb 2010

Study shows lactobacillus is effective in improving H. pylori-infected diseases

Helicobacter pylori (H. pylori) are considered to be the most important etiological agents of chronic gastritis. The eradication of H. pyloridepends on the combination of antibiotics and acid suppression drugs.

10 Feb 2010

Data provide key information about epigenetic profiles for gastric cancer

Gastric cancer, one of the most common types of cancer, is associated with high mortality rates. In the last decades, a decrease in the worldwide incidence has been observed with some changes in the therapeutic and diagnostic options.

10 Feb 2010

Research paves way for future vaccine against gastric adenocarcinoma

Despite a strong response from our immune defence, the body is unable to rid itself of the bacterium Helicobacter pylori. One reason for this is that this bacterium encourages elements of the immune response to remain in tissue, activating the wrong immune cells. Research results that pave the way for a future vaccine are now being published by the Sahlgrenska Academy at the University of Gothenburg, Sweden.

25 Jan 2010

Exalenz Bioscience finalizes production of its BreathID System for detecting H. pylori bacteria

Exalenz Bioscience has finalized production of the BreathID® and is preparing to ship the first devices and kits that are used in the detection of Helicobacter pylori bacteria. Additionally, in preparation for its American launch, the company is in the process of establishing national distribution channels. The company has recently announced the appointment of Mr. Dennis Boyle as Vice-President and National Manager in the USA. In his previous position, Mr. Boyle was director of sales and marketing to medical laboratories for Siemens USA.

21 Jan 2010

Study explains how H. pylori infection causes stomach cancer

Researchers report that Helicobacter pylori, the only bacterium known to survive in the harsh environment of the human stomach, directly activates an enzyme in host cells that has been associated with several types of cancer, including gastric cancer.

7 Jan 2010

Microbial Pathogenomics: A collection of reviews and future trends in bacterial pathogenomics

'Microbial Pathogenomics' contains a unique collection of reviews demonstrating how genomics has revolutionized our understanding of virulence, host-adaptation strategies and the evolution of bacterial pathogens. Current technologies - computational tools and functional approaches to genome analysis - are carefully documented and clearly illustrated.

23 Dec 2009

Exposure to common infections may increase stroke risk

Cumulative exposure to five common infection-causing pathogens may be associated with an increased risk of stroke, according to a report posted online today that will appear in the January 2010 print issue of Archives of Neurology, one of the JAMA/Archives journals.

10 Nov 2009

Study: Short-term use of COX-2 inhibitors may help prevent gastric cancer

Elevated expression of COX-2 is observed in a wide variety of human malignancies, including gastric cancer. Long-term high dose COX-2 inhibitors can inhibit gastric carcinogenesis in animal models, but the possible life-threatening cardiovascular adverse events limit its popular application. Therefore, it is important to evaluate the optimal intervention point of COX-2 inhibitors for inhibiting H. pylori-associated gastric carcinogenesis.

29 Oct 2009

Lifestyle and genetic factors are considered to play a major role in "Asian paradox"

Although Helicobacter pylori (H. pylori) has been classified as a class I (or definite) carcinogen by World Health Organization (WHO), the controversy as to why only a minority of infected patients develop gastric cancer still remains. Moreover, in Asian countries such as Indonesia, Japan, China, and Thailand, where the H. pylori infection rates are similar, there is a significant difference regarding the outcome of gastric cancer. That fact has been termed the "Asian paradox".

29 Oct 2009

Genomics can provide insights in understanding emerging infectious disease

This week, the Public Library of Science, an open-access publisher, presents the "Genomics of Emerging Infectious Disease," a collection of essays, perspectives, and reviews that explores how genomics-with all its associated tools and techniques-can provide insights into our understanding of emerging infectious disease.

27 Oct 2009

Study reveals LOAD therapy can eliminate bacterium in patients with gastritis and peptic ulcers

Helicobater pylori, a bacteria implicated in peptic ulcers and gastritis, was eradicated in 95 percent patients who took a 7-day course of combination therapy with levofloxacin, omeprazole, nitazoxanide (Alinia®) and doxycycline (LOAD) compared to eradication in only 80.9 percent of patients on lansoprazole, amoxicillin and clarithromycin (LAC) for seven days.

27 Oct 2009

Helicobacter pylori News and Research

JAMA study shows decline in incidence of gastric cancer for all age groups

New research shows link between infection-related diseases and risk of cancer

Link between IL-8, MIF gene polymorphisms and progression of atrophic gastritis and intestinal metaplasia

Antibiotics lower risk of developing gastric cancer

Beneficial Alzheimer's therapies, update on prevention efforts focused at ADI International Conference

Breastfeeding and better hygiene may protect against peptic ulcer bacterium infection

Pathogen study could provide new insights on gene regulation

Proteins found in intestines can recognize and kill bacteria that have human blood type molecules

Insight into mechanism H. pylori uses to evade the immune system

Study shows lactobacillus is effective in improving H. pylori-infected diseases

Data provide key information about epigenetic profiles for gastric cancer

Research paves way for future vaccine against gastric adenocarcinoma

Exalenz Bioscience finalizes production of its BreathID System for detecting H. pylori bacteria

Study explains how H. pylori infection causes stomach cancer

Microbial Pathogenomics: A collection of reviews and future trends in bacterial pathogenomics

Exposure to common infections may increase stroke risk

Study: Short-term use of COX-2 inhibitors may help prevent gastric cancer

Lifestyle and genetic factors are considered to play a major role in "Asian paradox"

Genomics can provide insights in understanding emerging infectious disease

Study reveals LOAD therapy can eliminate bacterium in patients with gastritis and peptic ulcers

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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