Induced Pluripotent Stem Cells News and Research

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Scientists uncover the cause of a rare fatal nerve disease

A new study has revealed the cause of Pelizaeus-Merzbacher syndrome and how simply adding a chemical that binds to iron, so it can be removed from the cell, enables the sick cells to grow back.

4 Oct 2019

Cardiac cells derived from skin samples help unravel genetic underpinnings of heart function

Genome-wide association studies have uncovered more than 500 genetic variants linked to heart function, everything from heart rate to irregular rhythms that can lead to stroke, heart failure or other complications.

30 Sep 2019

Functional three-organoid stem cell system could lead to unprecedented advances for precision medicine

Using iPS cells, a Japanese research group has successfully grown a connected set of organs at the same time, including a liver and a pancreas connected by a bile duct.

27 Sep 2019

Pros and cons of gene editing technology

CRISPR technology has greatly facilitated gene editing. Associate Professor Thorsten Müller from Ruhr-Universität Bochum and Dr. Hassan Bukhari from Harvard Medical School discuss its pros and cons in a review article in the journal "Trends in Cell Biology" from 12 September 2019.

17 Sep 2019

Cure for Rett Syndrome a step closer as scientists successfully reactivate 'back-up’ genes

A team headed by Vincent Pasque at his Lab at KU Leuven alongside researchers from the Jean-Christophe Marine lab and the Edith Heard lab have made a significant step towards developing a treatment for Rett syndrome and other X chromosome linked disorders.

17 Sep 2019

Scientists discover major regulator of schizophrenia that is active during early development

Researchers have discovered a gene that acts as a master regulator of schizophrenia during the early stages of human brain development.

12 Sep 2019

A gene that acts as master regulator of schizophrenia identified

Using computational tools to investigate gene transcription networks in large collections of brain tissues, a scientific team has identified a gene that acts as a master regulator of schizophrenia during early human brain development.

11 Sep 2019

LMRI scientists discover cause of debilitating eye disease

Scientists at the Lowy Medical Research Institute have discovered one cause of a progressive, debilitating eye disease called macular telangiectasia type 2 (MacTel).

11 Sep 2019

Neurobiological pathophysiology of schizophrenia differs based on gender

The neurobiological pathophysiology of schizophrenia differs significantly between males and females, according to a new study.

4 Sep 2019

Lab-grown brain organoids and the brains of preemie babies generate similar electrical impulses

Brain organoids — also called mini-brains — are 3D cellular models that represent aspects of the human brain in the laboratory. Brain organoids help researchers track human development, unravel the molecular events that lead to disease and test new treatments.

30 Aug 2019

New study provides unprecedented insights into retina's genetic code

Australian scientists have led the development of the world's most detailed gene map of the human retina, providing new insights which will help future research to prevent and treat blindness.

27 Aug 2019

Protein present in telomeres shows global action on genome which influences pleuripotency

Pluripotent cells can give rise to all cells of the body, a power that researchers are eager to control because it opens the door to regenerative medicine and organ culture for transplants.

21 Aug 2019

Mini kidneys grown in the lab could be used to better understand kidney diseases

An international team of researchers led by Nanyang Technological University, Singapore (NTU Singapore) has grown 'miniature kidneys' in the laboratory that could be used to better understand how kidney diseases develop in individual patients.

20 Aug 2019

Nanotechnology could boost stem cell transplantation research

Nanotechnology developed at Rutgers University-New Brunswick could boost research on stem cell transplantation, which may help people with Alzheimer's disease, Parkinson's disease, other neurodegenerative diseases and central nervous system injuries.

14 Aug 2019

UC San Diego researchers win $9 million funding to identify cellular cause of type 1 diabetes

University of California San Diego School of Medicine researchers have been awarded nearly $9 million to fund two multi-institutional research projects that use human pluripotent stem cells, CRISPR and human organoids to dissect beta cell defects and create a human cell model of type 1 diabetes aimed at identifying the elusive cellular actions leading to disease onset.

14 Aug 2019

Novel dual approach can be a promising way to enhance cardiac repair

As a medical emergency caused by severe cardiovascular diseases, myocardial infarction (MI) can inflict permanent and life-threatening damage to the heart.

12 Aug 2019

Researchers seek to understand the regenerative potential of newborn mammalian hearts

Unlike lower vertebrates, mammals are unable to repair their adult hearts after injuries that include heart attacks. This inability in humans leads to heart failure -- a deadly and costly disease that affects more than 5 million Americans.

10 Aug 2019

New method to enhance heart-attack repair using stem cell-derived cardiomyocytes

The heart cannot regenerate muscle tissue after a heart attack has killed part of the muscle wall. That dead tissue can strain surrounding muscle, leading to a lethal heart enlargement.

8 Aug 2019

New 3D-cardiac tissue platform can predict how heart responds to drugs

Researchers from TARA Biosystems, Inc. and GlaxoSmithKline today published data demonstrating that TARA's engineered heart-on-a-chip system replicated drug responses found in adult humans.

7 Aug 2019

First-of-its-kind study in space station seeks to find causes of major diseases

High above the Earth, researchers are conducting a first-of-its-kind study to help patients with Parkinson's disease and multiple sclerosis on the planet below. The International Space Station experiment is looking for what triggers these diseases by studying how nerve and immune brain cells interact.

1 Aug 2019