Large Intestine News and Research

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UH clinical trial to evaluate stool DNA testing for colon cancer

In a first-of-its-kind clinical trial, physician-scientists at University Hospitals (UH) Case Medical Center's Seidman Cancer Center and Case Western Reserve University School of Medicine are studying a promising new non-invasive technology for colon cancer screening. The four-year study is recruiting patients to compare the effectiveness of stool DNA (SDNA) testing with colonoscopy for detecting large colon polyps.

31 Mar 2012

National Colon Cancer Awareness Month attempts to widen screening efforts

March is the National Colon Cancer Awareness Month and to mark it Ferrell Hospital and Harrisburg Medical Center have teamed up with the American Cancer Society to provide free take-home colon cancer tests to anyone who is interested.

25 Mar 2012

Soy-based S-equol lowers HbA1c, LDL cholesterol and improves vascular stiffness

A 12-week treatment of the fermented soy germ-based nutritional supplement containing S-equol significantly lowered hemoglobin A1c (HbA1c), LDL cholesterol and improved vascular stiffness, all factors that occur as part of metabolic syndrome, according to a first-of-its-kind peer-reviewed study reported in a poster at the Women's Health 2012 annual meeting.

19 Mar 2012

Researchers identify molecule that helps decrease acute GVHD severity

Researchers have identified a molecule that helps control the severity of graft-versus-host disease, a life-threatening complication for many leukemia patients who receive a bone-marrow transplant.

12 Mar 2012

Colon cancer screening guidelines released

According to a new guidance statement from the American College of Physicians all adults should get screened for colon cancer once they get older to reduce their risk of dying from the nation's number two cancer killer.

7 Mar 2012

RV5 vaccination does not increase risk of intussusception in infants

Although some data have suggested a possible increased risk of intussusception (when a portion of the small or large intestine slides forward into itself, like a telescope) after administration of the pentavalent rotavirus vaccine in infants, an analysis that included almost 800,000 doses administered to U.S. infants found no increased risk of this condition following vaccination, according to a study in the February 8 issue of JAMA.

8 Feb 2012

High-fiber diet may raise risk of diverticulosis

For more than 40 years, scientists and physicians have thought eating a high-fiber diet lowered a person's risk of diverticulosis, a disease of the large intestine in which pouches develop in the colon wall. A new study of more than 2,000 people reveals the opposite may be true.

24 Jan 2012

EMA CHMP issues positive opinion to MSD's REMICADE for treatment of pediatric UC

MSD today announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) adopted a positive opinion recommending the use of REMICADE (infliximab) in the treatment of severely active ulcerative colitis (UC) in pediatric patients ages 6 to 17 years, who have had an inadequate response to conventional therapy, including corticosteroids and 6-mercaptopurine or azathioprine, or who are intolerant to or have medical contraindications for such therapies.

21 Jan 2012

Daily doses of S-equol reduce hot flashes in postmenopausal women

Daily doses of a soy germ-based nutritional supplement containing S-equol significantly improved menopausal symptoms, including significantly reducing hot flash frequency after 12 weeks according to a placebo-controlled study in postmenopausal Japanese women published in the peer-reviewed Journal of Women's Health.

5 Jan 2012

Study finds increase in incidence and prevalence of IBD

The incidence and prevalence of inflammatory bowel disease (IBD) are increasing with time and in different regions around the world, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association.

5 Jan 2012

New form of esophagectomy for treatment of severe cancer

Surgeons at Mayo Clinic in Arizona have perfected a new procedure that offers a less invasive option in the treatment of one of the most severe cancers.

29 Dec 2011

Large-intestine bacteria may help prevent obesity

Bacteria living in people's large intestine may slow down the activity of the "good" kind of fat tissue, a special fat that quickly burns calories and may help prevent obesity, scientists are reporting in a new study.

22 Dec 2011

Kaiser Permanente Southern California awards $150,000 to 82 nursing students

Kaiser Permanente Southern California continues its long-standing commitment to nursing education, awarding $150,000 to 82 nursing students. In Northern California, 93 students received scholarships totaling $157,000.

12 Dec 2011

Probiotic before radiation therapy can protect intestine from damage

Scientists at Washington University School of Medicine in St. Louis have shown that taking a probiotic before radiation therapy can protect the intestine from damage — at least in mice.

17 Nov 2011

Link between deprivation and bowel cancer deaths in men

Deprived men are more likely to die from bowel cancer than men from the most affluent section of society, new research presented at the NCRI Cancer Conference in Liverpool this week shows.

7 Nov 2011

Early diagnosis of large intestine cancer could be feasible in the long term

Itxaro Perez, a biochemist at the University of the Basque Country (UPV/EHU), has contributed in such a way that, in the long term, the early diagnosis of cancer of the large intestine could be feasible.

4 Nov 2011

NPS announces new data from GATTEX Phase 3 study on short bowel syndrome

NPS Pharmaceuticals, Inc., a specialty pharmaceutical company developing innovative therapeutics for rare gastrointestinal and endocrine disorders, today announced new data from STEPS 2, a long-term open-label study, showing that GATTEX (teduglutide) was associated with achieving and maintaining clinically meaningful reductions in parenteral nutrition (PN) and intravenous (IV) fluid volume in adult subjects with short bowel syndrome.

1 Nov 2011

Limited alcohol consumption can cause gastrointestinal problems

Just one drink per day for women -- two for men -- could lead to small intestinal bacterial overgrowth (SIBO) and subsequently cause gastrointestinal symptoms like bloating, gas, abdominal pain, constipation and diarrhea, according to the results of a new study unveiled today at the American College of Gastroenterology's (ACG) 76th Annual Scientific meeting in Washington, DC.

31 Oct 2011

Effects of fruit and vegetable consumption on colorectal cancer

The effects of fruit and vegetable consumption on colorectal cancer (CRC) appear to differ by site of origin, according to a new study published in the October issue of the Journal of the American Dietetic Association.

26 Sep 2011

Fruits and veggies may prevent bowel cancer but not fruit juices: Study

Scientists claim that a glass of juice contains so much sugar it actually increases the risk of certain cancers, rather than preventing them. In fact, by the time the drink has been processed and packaged, many of the ingredients in fruit that protect against tumors have been lost, they say. The Perth team also said that many things found in fruit which help protect against bowel cancer – including fibre, vitamin C and chemicals known as antioxidants – are lost during the juice’s processing.

26 Sep 2011