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New book by Virginia Tech researchers explains a set of techniques to model the immune system

The complexity of the human immune response has been difficult to characterize on a 'big picture' level, but researchers at the Virginia Bioinformatics Institute at Virginia Tech have written the book on how it can be done.

5 Nov 2015

Environmental and lifestyle factors contribute to development of celiac disease

Celiac disease incidence has increased among Swedish children between 2 to 15 years. The significant escalation in celiac disease can be associated with planned caesarean sections, urinary tract infections during pregnancy, season of birth and being born in south Sweden.

3 Nov 2015

Diet missing soluble fiber promotes inflammation in the intestines, leading to weight gain

Eating too much high-fat, high-calorie food is considered the primary cause of obesity and obesity-related disease, including diabetes. While the excess calories consumed are a direct cause of the fat accumulation, scientists suspect that low-grade inflammation due to an altered gut microbiome may also be involved.

30 Oct 2015

Australian researchers find a way to boost cross-protective capabilities of influenza A vaccine

Australian researchers have found a way to boost the effectiveness and cross-protective capabilities of an influenza A vaccine by adding a simple component. Published this week in mBio, an online open-access journal of the American Society for Microbiology, the research in mice could lead to better seasonal flu vaccines for humans, and also vaccines that could provide community protection in the early stages of an outbreak of a novel flu virus strain.

28 Oct 2015

Infections with Lone star ticks appear to be surging but deaths are not, new study reveals

A mild disease spread by the aggressive Lone star tick that is now colonizing large swaths of the United States is being mistaken for Rocky Mountain spotted fever, according to a new study from scientists at the U.S. Centers for Disease Control and Prevention.

28 Oct 2015

Study links antibiotic use during childhood to weight gain

Children who take antibiotics during the course of their childhood gain weight more quickly than those who do not, according to a study published in the International Journal of Obesity.

22 Oct 2015

Children who receive repeated antibiotics gain weight faster over time

Kids who receive antibiotics throughout the course of their childhoods gain weight significantly faster than those who do not, according to new Johns Hopkins Bloomberg School of Public Health research.

22 Oct 2015

Set of genes identified in human genome essential for survival, proliferation of human cell lines

Using two complementary analytical approaches, scientists at Whitehead Institute and Broad Institute of MIT and Harvard have for the first time identified the universe of genes in the human genome essential for the survival and proliferation of human cell lines or cultured human cells.

16 Oct 2015

Researchers create high resolution images of telomerase that plays major role in cancer, aging

An enzyme called telomerase plays a significant role in aging and most cancers, but until recently many aspects of the enzyme's structure could not be clearly seen.

16 Oct 2015

Study finds link between microbial signatures and triple negative breast cancer

Cancer is a result of normal cellular functions going wildly awry on a genetic level. That fact has been known for some time, but increasing evidence is showing that the human microbiome, the diverse population of microorganisms within every person, may play a key role in either setting the stage for cancer or even directly causing some forms of it.

16 Oct 2015

Neutrophils kill invading microorganisms, starve microbes to death

The most frequent immune cells in the human blood, so-called neutrophils, efficiently kill invading microorganisms and slowly starve microbes to death by removing crucial trace elements. This is shown by researchers from Umeå University in Sweden in a study published in a special issue of Metallomics.

15 Oct 2015

Different Crohn's disease treatments affect children's gut microbes in distinct ways

Different treatments for Crohn's disease in children affects their gut mi-crobes in distinct ways, which has implications for future development of microbial-targeted therapies for these patients, according to a study led by researchers from the Perelman School of Medicine at the University of Pennsylvania.

15 Oct 2015

Forces in external environmental and oxidation are greatest threats to DNA, study finds

A study led by Indiana University biologist Patricia Foster and colleagues has found that forces in the external environment and oxidation are the greatest threats to an organism's ability to repair damage to its own DNA.

14 Oct 2015

Rebiotix's RBX2660 receives FDA Breakthrough Therapy designation for treatment of recurrent C diff infection

Rebiotix Inc. today announced that U.S. Food and Drug Administration has designated its lead Microbiota Restoration Therapy (MRT) RBX2660 as a Breakthrough Therapy for the treatment of recurrent Clostridium difficile (C diff) infection, a challenging to treat gastrointestinal (GI) infection that causes 29,000 deaths in the U.S. annually.

12 Oct 2015

FDA orders three duodenoscope manufacturers in the U.S. to conduct postmarket surveillance studies

The U.S. Food and Drug Administration today ordered the three manufacturers of duodenoscopes marketed in the U.S. to conduct postmarket surveillance studies to better understand how the devices are reprocessed in real-world settings.

12 Oct 2015

FDA permits marketing of first CSF nucleic acid-based test for detection of multiple pathogens

The U.S. Food and Drug Administration today allowed marketing of the first cerebrospinal fluid (CSF) nucleic acid-based test for simultaneous detection of multiple pathogens that can cause central nervous system infections.

12 Oct 2015

Scientists calculate precise measurements of heritability in nine pediatric-onset autoimmune diseases

Scientists have calculated more precise measurements of heritability--the influence of underlying genes--in nine autoimmune diseases that begin in childhood. The research may strengthen researchers' abilities to better predict a child's risk for associated autoimmune diseases.

9 Oct 2015

Microorganism News and Research

New book by Virginia Tech researchers explains a set of techniques to model the immune system

Environmental and lifestyle factors contribute to development of celiac disease

Diet missing soluble fiber promotes inflammation in the intestines, leading to weight gain

Australian researchers find a way to boost cross-protective capabilities of influenza A vaccine

Infections with Lone star ticks appear to be surging but deaths are not, new study reveals

Study links antibiotic use during childhood to weight gain

Children who receive repeated antibiotics gain weight faster over time

Set of genes identified in human genome essential for survival, proliferation of human cell lines

Researchers create high resolution images of telomerase that plays major role in cancer, aging

Study finds link between microbial signatures and triple negative breast cancer

Neutrophils kill invading microorganisms, starve microbes to death

Different Crohn's disease treatments affect children's gut microbes in distinct ways

Forces in external environmental and oxidation are greatest threats to DNA, study finds

Rebiotix's RBX2660 receives FDA Breakthrough Therapy designation for treatment of recurrent C diff infection

FDA orders three duodenoscope manufacturers in the U.S. to conduct postmarket surveillance studies

FDA permits marketing of first CSF nucleic acid-based test for detection of multiple pathogens

Scientists calculate precise measurements of heritability in nine pediatric-onset autoimmune diseases

UNC researchers identify a type of vaginal bacteria that can protect women from HIV

Gut microbiome can play significant role in the body's response to gluten

Bacteria does not develop antimicrobial resistance in wastewater treatment plants

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