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Evolutionary history reveals the function of fish and human bitter receptors

To evaluate the chemical composition of food from a physiological point of view, it is important to know the functions of the receptors that interact with food ingredients.

2 Feb 2021

Remdesivir, given to half of hospitalized covid patients in U.S., is big win for Gilead — boosted by taxpayers

It was the end of April — just as the U.S. confirmed its millionth covid-19 case and 50,000 deaths — when White House adviser Dr. Anthony Fauci announced "highly significant" news about a drug called remdesivir.

27 Jan 2021

New data shows that mINDY gene is involved in blood pressure regulation

Authors from the German Center for Diabetes Research (DZD) presented data showing that the longevity gene mammalian Indy (mINDY) is involved in blood pressure regulation in the Journal of Clinical Investigation (JCI) insight.

27 Jan 2021

Novel non-steroid topical cream can safely and effectively treat plaque psoriasis

Psoriasis is a chronic inflammatory skin disease characterized by erythematous (red) patches and plaques.

19 Jan 2021

Researchers use urine test to identify and verify a patient's type of asthma

In a new study, researchers at Karolinska Institutet in Sweden have used a urine test to identify and verify a patient's type of asthma.

13 Jan 2021

SARS-CoV-2 infection shown to reduce the expression of vitamin D pathway components

A recent computational study from India implicated a dysregulated vitamin D pathway in the pathobiology of the infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – and opened the door for experimental validation of these observations.

23 Dec 2020

Study: Exposure to metals may disrupt a woman's hormones during pregnancy

Exposure to metals such as nickel, arsenic, cobalt and lead may disrupt a woman's hormones during pregnancy, according to a Rutgers study.

21 Dec 2020

COVID-19 pandemic highlights the risk of using systemic corticosteroids

Healthcare workers in tropical and sub-tropical settings where strongyloidiasis is prevalent or caring for patients who have travelled to such areas, need to maintain a high level of awareness about the use of corticosteroids, including when this class of anti-inflammatories is given to patients suspected of infection with SARS-CoV-2.

17 Dec 2020

HDL nanoparticles prevent cholesterol movement at membrane receptor to inhibit entry of SARS-CoV-2 pseudovirus in cell culture

As researchers strive to find safe therapeutics for COVID 19, a study suggests that preventing the movement of cholesterol may inhibit viral entry by up to 80%.

17 Dec 2020

A battle-weary Seattle hospital fights the latest COVID surge

As hospitals across the country weather a surge of COVID-19 patients, in Seattle — an early epicenter of the outbreak — nurses, respiratory therapists and physicians are staring down a startling resurgence of the coronavirus that’s expected to test even one of the best-prepared hospitals on the pandemic’s front lines.

10 Dec 2020

Researchers develop new approach for COVID-19 testing

Researchers from UC San Francisco and the Chan Zuckerberg Biohub have developed a new approach for COVID-19 testing that detects a distinct pattern of immune gene expression in infected individuals.

7 Dec 2020

Study shows how parasite that causes Chagas disease resists current therapies

New insight on how a parasite can resist current therapies has been published today in the open-access eLife journal.

2 Dec 2020

Mild electrical stimulation with heat shock exerts protective effect against nephrotic syndrome

A research team from Kumamoto University in Japan has found that the combination of weak pulsed electrical current and heat exerts anti-inflammatory and anti-fibrotic effects in the kidneys, as well as a protective effect against nephrotic syndrome (NS) by inhibiting apoptosis (cell death) of kidney cells.

30 Nov 2020

Potential treatment could reduce heart failure after a significant heart attack

While there are therapies to aid in overall heart health, there are very few preventative therapies for heart failure after a significant heart attack, a serious condition that has a very significant mortality.

24 Nov 2020

Masks can cause more problems in people with skin allergies

Throughout the course of the COVID-19 pandemic, those able to wear a face mask have been encouraged to do so to prevent transmission of the virus. For some people with skin allergies, wearing a mask can cause further problems.

17 Nov 2020

Corticosteroids can help in survival of elderly patients with severe COVID-19

A new study group based in France have looked at the rates of survival among elderly patients with COVID-19 who were administered with corticosteroids.

16 Nov 2020

New procedure offers lasting pain relief for patients with osteoarthritis

A novel outpatient procedure offers lasting pain relief for patients suffering from moderate to severe arthritis in their hip and shoulder joints, according to a study presented at the annual meeting of the Radiological Society of North America (RSNA).

16 Nov 2020

Antiviral immune response is suppressed in COVID-19 patients compared to flu patients

Rather than life-threatening hyperinflammation, most adults with moderate-to-severe COVID-19 have a suppressed viral immune response when compared to adults with another viral respiratory infection, influenza. St. Jude Children's Research Hospital and Washington University School of Medicine in St. Louis led research that suggests most COVID-19 patients are not candidates for treatment with steroids such as dexamethasone.

16 Nov 2020

Study explains why anti-inflammatory drugs benefit only few people with severe COVID-19

The turning point for people with COVID-19 typically comes in the second week of symptoms. As most people begin to recover, a few others find it increasingly difficult to breathe and wind up in the hospital.

16 Nov 2020

Elastic-free facial masks could benefit individuals with contact dermatitis during COVID-19

A University of Cincinnati immunologist is recommending that individuals with contact dermatitis choose facial masks made without elastic or rubber that allow them to stay safe in the midst of COVID-19 while avoiding possible allergic reactions.

15 Nov 2020

Steroid News and Research

Evolutionary history reveals the function of fish and human bitter receptors

Remdesivir, given to half of hospitalized covid patients in U.S., is big win for Gilead — boosted by taxpayers

New data shows that mINDY gene is involved in blood pressure regulation

Novel non-steroid topical cream can safely and effectively treat plaque psoriasis

Researchers use urine test to identify and verify a patient's type of asthma

SARS-CoV-2 infection shown to reduce the expression of vitamin D pathway components

Study: Exposure to metals may disrupt a woman's hormones during pregnancy

COVID-19 pandemic highlights the risk of using systemic corticosteroids

HDL nanoparticles prevent cholesterol movement at membrane receptor to inhibit entry of SARS-CoV-2 pseudovirus in cell culture

A battle-weary Seattle hospital fights the latest COVID surge

Researchers develop new approach for COVID-19 testing

Study shows how parasite that causes Chagas disease resists current therapies

Mild electrical stimulation with heat shock exerts protective effect against nephrotic syndrome

Potential treatment could reduce heart failure after a significant heart attack

Masks can cause more problems in people with skin allergies

Corticosteroids can help in survival of elderly patients with severe COVID-19

New procedure offers lasting pain relief for patients with osteoarthritis

Antiviral immune response is suppressed in COVID-19 patients compared to flu patients

Study explains why anti-inflammatory drugs benefit only few people with severe COVID-19

Elastic-free facial masks could benefit individuals with contact dermatitis during COVID-19

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