Whole Genome Sequencing News and Research

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Study results provide strong evidence for association of genetic markers to long COVID mappable to fatigue

Researchers analyzed polygenic risk scores in whole genome sequences obtained from blood samples of long COVID patients to determine genomic predictors of long COVID.

2 Mar 2023

SARS-CoV-2 BA.1 and BA.2 breakthrough infections likely protect against BA.4 infection

Omicron BTIs induce durable neutralizing immune responses by recalling cross-reactive and vaccine-induced memory B lymphocytes.

1 Mar 2023

The evolution of transmissible variants harboring mutations consistent with immune escape in mild community COVID-19 cases

Researchers investigate whether transmissible SARS-CoV-2 variants developed during infection by culturing and sequencing strains obtained from serial oral and nasal samples of community-residing COVID-19 patients.

28 Feb 2023

Regulations limiting antibiotics in livestock can significantly impact human health

A California policy restricting antibiotic use in animals raised for food is associated with a reduction in one type of antibiotic-resistant infection in people in the state, according to a new study published today in the journal Environmental Health Perspectives.

22 Feb 2023

Whole genome sequencin provides clearest picture of the genetic changes leading to Hodgkin lymphoma

To create the most effective, personalized treatment plans for patients with Hodgkin lymphoma or other cancers, scientists and clinicians need the clearest picture of the genetic changes leading to the cancer's development.

21 Feb 2023

After a previous BA.1 infection, Omicron BA.4/5 infection is more likely than BA.2

In a recent study published in the journal Eurosurveillance, researchers investigated whether prior severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and/or coronavirus disease 2019 (COVID-19) vaccination protected against SARS-CoV-2 Omicron variant of concern (VOC) BA.4/5 sub-VOC or BA.2 sub-VOC infections.

19 Feb 2023

Genes encoding T cell receptors vary greatly between persons and populations, study reveals

Researchers from Karolinska Institutet have discovered that the genes encoding our T cell receptors vary greatly between persons and populations, which may explain why we respond differently to for example infections.

16 Feb 2023

Death of a zoo hippopotamus underscores the species’ susceptibility to SARS-CoV-2

A recent study investigated the death of a hippopotamus at a zoo in Hanoi, Vietnam.

16 Feb 2023

Isolation of Burkholderia thailandensis from the environment

A new study in Emerging Infectious Diseases aimed to detect and isolate B. thailandensis from water and soil samples collected from Puerto Rico between December 2018 and March 2020 as well as Texas between November 2019 to November 2020.

15 Feb 2023

UT Southwestern researchers map gene control elements responsible for coordinating heartbeats

UT Southwestern Medical Center researchers have mapped gene control elements in specialized cardiac cells responsible for coordinating heartbeats.

13 Feb 2023

A single base-resolution sequencing methodology that sequences the two most common cytosine modifications in a single workflow

Researchers developed a WGS method that read four canonical DNA bases, viz., adenine (A), cytosine (C), guanine (G), and thymine (T) plus 5mC and 5hmC, epigenetic variants of unmodified C to yield an accurate six-letter digital readout in a single workflow.

9 Feb 2023

Comparison of pre- and post-Omicron disease severity among unvaccinated people without risk factors

In a recent study posted to the medRxiv* preprint server, researchers in Sweden investigated coronavirus disease 2019 (COVID-19) severity among unvaccinated adults during the periods of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern (VOC) dominance compared to the severity of pre-Omicron VOC infections.

8 Feb 2023

Macrophages suppress Escherichia coli LF82 Gally prophage lytic cycle

Researchers analyze prophages of the LF82 strain of adherent-invasive Escherichia coli to better understand their behavior in vitro and within macrophages.

8 Feb 2023

COVID-19 vaccination increases saliva antibody levels after asymptomatic infection

Researchers correlate SARS-CoV-2 load and neutralizing capacity of all saliva immunoglobulins isotypes in asymptomatic individuals.

8 Feb 2023

Risk factors for Omicron reinfections among previously infected frontline workers in the United States

Researchers examined a prospective cohort of frontline workers in the United States (US) previously infected with SARS-CoV-2. They attempted to identify risk factors that made this highly vulnerable population prone to reinfection by SARS-CoV-2 new variant of concern (VOC), Omicron, known for its high immune evading potential.

1 Feb 2023

Prenatal MRI helps visualize SARS-CoV-2 infection-induced abnormalities in the placenta and fetuses

Researchers performed a prospective case-control study on pregnant women with confirmed coronavirus disease 2019 (COVID-19).

26 Jan 2023

Scientists illuminate how blood cancer treatments can lead to therapy-related myeloid neoplasms

Scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have illuminated how treatments for multiple myeloma and other aggressive blood cancers can lead to future malignancies, called therapy-related myeloid neoplasms (tMNs).

25 Jan 2023

Whole Genome Sequencing News and Research

Study results provide strong evidence for association of genetic markers to long COVID mappable to fatigue

SARS-CoV-2 BA.1 and BA.2 breakthrough infections likely protect against BA.4 infection

The evolution of transmissible variants harboring mutations consistent with immune escape in mild community COVID-19 cases

Regulations limiting antibiotics in livestock can significantly impact human health

Whole genome sequencin provides clearest picture of the genetic changes leading to Hodgkin lymphoma

After a previous BA.1 infection, Omicron BA.4/5 infection is more likely than BA.2

Genes encoding T cell receptors vary greatly between persons and populations, study reveals

Death of a zoo hippopotamus underscores the species’ susceptibility to SARS-CoV-2

Isolation of Burkholderia thailandensis from the environment

UT Southwestern researchers map gene control elements responsible for coordinating heartbeats

A single base-resolution sequencing methodology that sequences the two most common cytosine modifications in a single workflow

Comparison of pre- and post-Omicron disease severity among unvaccinated people without risk factors

Macrophages suppress Escherichia coli LF82 Gally prophage lytic cycle

COVID-19 vaccination increases saliva antibody levels after asymptomatic infection

Risk factors for Omicron reinfections among previously infected frontline workers in the United States

Prenatal MRI helps visualize SARS-CoV-2 infection-induced abnormalities in the placenta and fetuses

Scientists illuminate how blood cancer treatments can lead to therapy-related myeloid neoplasms

UK set to boost genomics expertise through a landmark partnership with Thailand

Tight transmission bottlenecks may limit the evolution of SARS-CoV-2 variants

Exploring a novel amplicon-based mpox virus sequencing strategy

Sequencing & Genomics: Elevating Science and Healthcare eBook

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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