Biochemistry News and Research

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Plant-based drug for hemophilia shows promise in animal models

People with hemophilia require regular infusions of clotting factor to prevent them from experiencing uncontrolled bleeding. But a significant fraction develop antibodies against the clotting factor, essentially experiencing an allergic reaction to the very treatment that can prolong their lives.

13 Feb 2017

Long-term use of testosterone therapy in hypogonadal men may reduce risk of death from CV disease

Despite the continued controversy surrounding the use of testosterone in men who have testosterone deficiency (hypogonadism), a new study has found that long-term use of testosterone therapy not only improves vigor and vitality, but may reduce the risk of death due to cardiovascular (CV) disease.

13 Feb 2017

Duke Health researchers identify potential new drug target for Huntington's disease

The loss of motor function and mental acuity associated with Huntington's disease might be treatable by restoring a cellular quality control process, which Duke Health researchers have identified as a key factor in the degenerative illness.

13 Feb 2017

Study reveals new role for cancer drug in tumor immunology

A drug first designed to prevent cancer cells from multiplying has a second effect: it switches immune cells that turn down the body's attack on tumors back into the kind that amplify it. This is the finding of a study led by researchers from NYU Langone Medical Center and published recently in Cancer Immunology Research.

13 Feb 2017

Defective brain cells disposing toxic proteins may be linked to neurodegenerative diseases

Rutgers scientists say neurodegenerative diseases like Alzheimer's and Parkinson's may be linked to defective brain cells disposing toxic proteins that make neighboring cells sick.

10 Feb 2017

UCI researchers create unique VMT platform with potential for anti-cancer drug screening

Led by UCI professor of molecular biology & biochemistry Christopher C.W. Hughes, the research team successfully established multiple vascularized micro-organs on an industry-standard 96-well plate.

8 Feb 2017

UNC scientists confirm and clarify key molecular details of nucleotide excision repair

Day in and day out, in our bodies, the DNA in cells is damaged for a variety of reasons, and thus intercellular DNA-repair systems are fundamental to the maintenance of life.

8 Feb 2017

Study reveals potentially key molecular process that occurs in infective endocarditis

The human mouth can harbour more than 700 different species of bacteria. Under normal circumstances these microbes co-exist with us as part of our resident oral microbiota.

7 Feb 2017

UNC scientists isolate protein that could play role in asthmatics

Researchers at the UNC School of Medicine believe they have isolated a protein that, when missing or depleted, can cause airway constriction, production of mucus, chest tightness, and difficulty breathing for the 334 million people worldwide who suffer from asthma.

6 Feb 2017

New discovery could lead to development of new cancer treatments

Macrophages are a type of white blood cell that can engulf and destroy cancer cells. A research group led by Professor MATOZAKI Takashi, Associate Professor MURATA Yoji, and YANAGITA Tadahiko, discovered that by using an antibody for a particular protein found on macrophages, the macrophage is activated, and cancer cells are effectively eliminated.

6 Feb 2017

Cancer drug could promote regeneration of damaged heart muscle, research shows

An anticancer agent in development promotes regeneration of damaged heart muscle 0- an unexpected research finding that may help prevent congestive heart failure in the future.

3 Feb 2017

Single Molecule Detection of Proteins in Single Cells

We developed this technology almost 10 years ago. It was developed after a key experiment was carried out by David Rissin, who was a PhD candidate in my laboratory at the time.

From Pittcon 3 Feb 2017

Virginia Tech researchers receive NIH grant to improve malaria drug

As long as parasites continue to mount resistance to malaria drugs, scientists will be faced with the task of developing new, improved pharmaceuticals.

3 Feb 2017

Johns Hopkins researchers uncover mechanism in chikungunya virus that controls disease severity

Researchers led by the Johns Hopkins Bloomberg School of Public Health have identified a mechanism by which the chikungunya virus infects healthy cells and controls how severe the disease it causes will be, a mechanism they believe can be found in a number of other related viruses for which there are no treatments or licensed vaccines.

31 Jan 2017

Jefferson researchers reveal new insight into two states of viral protein

To generate swarms of new viral particles, a virus hijacks a cell into producing masses of self-assembling cages that are then loaded with the genetic blueprint for the next infection.

31 Jan 2017

Virginia Tech researchers find new strategy to prevent inflammatory bowel disease, colon cancer

Could inflammatory bowel disease and colon cancer be prevented by changing the shape of a single protein?There is an intimate link between uncontrolled inflammation in the gut associated with inflammatory bowel disease and the eventual development of colon cancer.

27 Jan 2017

Increasing idiopathic pulmonary fibrosis research

IPF is an incurable lung condition with the average life expectancy following diagnosis being just three years. It’s one of the many types of interstitial lung disease (ILD). Interstitial means that the disease affects the interstitium, a lace-like network of tissue that supports the air sacs (alveoli) in your lungs.

From Asthma + Lung UK 25 Jan 2017

Researchers identify new principle for how epigenetic changes can occur

In a new study, researchers at Uppsala University have found evidence of a new principle for how epigenetic changes can occur. The principle is based on an enzyme, tryptase, that has epigenetic effects that cause cells to proliferate in an uncontrolled manner.

20 Jan 2017

Researchers unravel bacterial protein structure that could pave way for new antibiotics

Bacterial cells have an added layer of protection, called the cell wall, that animal cells don't. Assembling this tough armor entails multiple steps, some of which are targeted by antibiotics like penicillin and vancomycin.

12 Jan 2017

UCM scientists design biosensor capable of detecting cancer autoantibodies at early stages

Before a malignant tumor is developed, the immune system tries to fight against proteins that are altered during their formation, producing certain cancer antibodies.

11 Jan 2017

Biochemistry News and Research

Plant-based drug for hemophilia shows promise in animal models

Long-term use of testosterone therapy in hypogonadal men may reduce risk of death from CV disease

Duke Health researchers identify potential new drug target for Huntington's disease

Study reveals new role for cancer drug in tumor immunology

Defective brain cells disposing toxic proteins may be linked to neurodegenerative diseases

UCI researchers create unique VMT platform with potential for anti-cancer drug screening

UNC scientists confirm and clarify key molecular details of nucleotide excision repair

Study reveals potentially key molecular process that occurs in infective endocarditis

UNC scientists isolate protein that could play role in asthmatics

New discovery could lead to development of new cancer treatments

Cancer drug could promote regeneration of damaged heart muscle, research shows

Single Molecule Detection of Proteins in Single Cells

Virginia Tech researchers receive NIH grant to improve malaria drug

Johns Hopkins researchers uncover mechanism in chikungunya virus that controls disease severity

Jefferson researchers reveal new insight into two states of viral protein

Virginia Tech researchers find new strategy to prevent inflammatory bowel disease, colon cancer

Increasing idiopathic pulmonary fibrosis research

Researchers identify new principle for how epigenetic changes can occur

Researchers unravel bacterial protein structure that could pave way for new antibiotics

UCM scientists design biosensor capable of detecting cancer autoantibodies at early stages

Binding kinetics in drug discovery eBook eBook

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