Pathogen News and Research

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Researchers identify CoV Mac1 proteins as a potential SARS-CoV-2 drug target

A recent study by researchers at the University of Kansas and published on the preprint server bioRxiv* reveals that Mac1 protein implicated in the infection process of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has a strikingly similar structure and activity in all coronaviruses – suggesting that possible future treatments targeting this protein may exert broad antiviral activity.

13 May 2020

U of A researchers and Tonix Pharmaceuticals join forces to develop, test COVID-19 vaccine

University of Alberta researchers launched a joint effort with U.S.-based Tonix Pharmaceuticals to develop and test a vaccine against COVID-19.

13 May 2020

New study investigates the effect of asymptomatic COVID-19 transmission

COVID-19's rapid spread throughout the world has been fueled in part by the virus' ability to be transmitted by people who are not showing symptoms of infection.

13 May 2020

Scientists are looking for alternate methods to predict the spread of COVID-19

With the ongoing challenges associated with large-scale testing for COVID-19--including test kit shortages, stringent testing criteria and the inherent limitations of current tracking systems on mildly symptomatic and asymptomatic populations, scientists are looking for alternate methods to boost testing in order to predict the spread of the disease.

13 May 2020

Passive immummization can offer instant, short-term fortification against infectious agents

The worldwide COVID-19 pandemic has infected more than 4 million people and killed close to 280,000.1 Finding a vaccine has become a global public health priority.

13 May 2020

Study: Diarrhea-causing bacteria provoke host's response to increase infectivity

A type of E. coli bacteria that causes bloody diarrhea uses an amino acid produced by the body in response to infection to intensify its symptoms, according to a new study from UT Southwestern scientists.

12 May 2020

Study sheds more light on the evolutionary ancestry of SARS-CoV-2

There is ongoing debate among policymakers and the general public about where SARS-CoV-2, the virus that causes COVID-19, came from. While researchers consider bats the most likely natural hosts for SARS-CoV-2, the origins of the virus are still unclear.

12 May 2020

Study provides genetic explanation behind the sex bias observed in certain diseases

Some diseases exhibit a clear sex bias, occurring more often, hitting harder or eliciting different symptoms in men or women.

12 May 2020

Hydroxychloroquine is not effective against COVID-19, extensive U.S. study shows

Over the past few months, doctors resorted to repurposing medicines that have already been approved for other diseases to treat coronavirus patients. One drug that was widely used in the pandemic, hydroxychloroquine, has been found to be ineffective in treating the viral infection.

11 May 2020

GCS centers support research to fight against global COVID-19 pandemic

In December 2019, the world learned of a new and deadly pathogen. News coming out of Wuhan, China confirmed public health experts' worst fears--a novel coronavirus appeared to have jumped from animals to humans.

11 May 2020

Study shows COVID-19 vulnerability is highly dependent on host genetic architecture

A new US study available on the preprint server medRxiv reveals certain genetic variations that are associated with infection susceptibility and diverse clinical presentation of coronavirus disease (COVID-19) – including asymptomatic cases and severe forms of the disease in younger patients.

10 May 2020

Study sheds light on how a cellular pathway in plants senses danger signals

In nature, every species must be equipped with a strategy to be able to survive in response to danger. Plants, too, have innate systems that are triggered in response to a particular threat, such as insects feeding on them.

8 May 2020

Children are immune prepared for SARS-CoV-2

At least 30 new diseases have emerged in the last 20 years and now together threaten the health of hundreds of millions of people. For many of these diseases, there is no treatment, cure, or vaccine. While most of these diseases are dangerous to children, especially those younger than five years old, the novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), seems to spare most of them.

8 May 2020

Pangolins may be the key to new COVID-19 treatments

Researchers at the Medical University of Vienna, Austria, have made an important discovery about the immune response to coronaviruses in pangolins that could point to new approaches for treating human cases of infection.

8 May 2020

Antibodies from llamas may hold cure for novel coronavirus SARS-CoV-2

As scientists across the globe race to find an effective treatment for the novel coronavirus, a team of scientists believe that a four-year-old llama named Winter may hold the key to fight the coronavirus disease (COVID-19).

7 May 2020

SARS-CoV-2 found in semen of COVID-19 patients

Since the novel coronavirus, now called the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged in December 2019, viral loads have been detected in body fluids, such as urine samples, saliva, stool samples, and in the gastrointestinal tract. Now, a new study reveals the SARS-CoV-2 virus in semen.

7 May 2020

Low CD8 and NK cell counts in the lung linked to high SARS-CoV-2 ACE2 receptor levels

A new study published on the preprint server bioRxiv in April 2020 reports that low levels of specific immune cells, namely, CD8 T cells and NK cells, are linked to higher expression of the ACE2 molecule, which acts as a receptor for the CoV.

6 May 2020

Combination therapy trial to understand the biology, spread, treatment of COVID-19

The HonorHealth Research Institute and HonorHealth announced today the successful enrollment on a novel combination of atovaquone and azithromycin in patients with moderate-to-severe COVID-19 infection.

6 May 2020

New breakthrough may help cure prion disease

A molecular biologist at the University of Massachusetts Amherst who has for decades studied the nightmarish group of fatal diseases caused by prions - chronic wasting disease in deer, mad cow in cattle and its human analog - credits a middle-of-the-night dream for a crucial insight, a breakthrough she hopes could lead to a cure.

6 May 2020

Human to Labskin Skin Models for Dermatology Research

A Human Skin Equivalent (HSE) skin model used for dermatology research, made from the same primary human cells but grown to a defined specification in a laboratory and not as complex as Human skin, lacking hair follicles and immune cells.

6 May 2020

Pathogen News and Research

Researchers identify CoV Mac1 proteins as a potential SARS-CoV-2 drug target

U of A researchers and Tonix Pharmaceuticals join forces to develop, test COVID-19 vaccine

New study investigates the effect of asymptomatic COVID-19 transmission

Scientists are looking for alternate methods to predict the spread of COVID-19

Passive immummization can offer instant, short-term fortification against infectious agents

Study: Diarrhea-causing bacteria provoke host's response to increase infectivity

Study sheds more light on the evolutionary ancestry of SARS-CoV-2

Study provides genetic explanation behind the sex bias observed in certain diseases

Hydroxychloroquine is not effective against COVID-19, extensive U.S. study shows

GCS centers support research to fight against global COVID-19 pandemic

Study shows COVID-19 vulnerability is highly dependent on host genetic architecture

Study sheds light on how a cellular pathway in plants senses danger signals

Children are immune prepared for SARS-CoV-2

Pangolins may be the key to new COVID-19 treatments

Antibodies from llamas may hold cure for novel coronavirus SARS-CoV-2

SARS-CoV-2 found in semen of COVID-19 patients

Low CD8 and NK cell counts in the lung linked to high SARS-CoV-2 ACE2 receptor levels

Combination therapy trial to understand the biology, spread, treatment of COVID-19

New breakthrough may help cure prion disease

Human to Labskin Skin Models for Dermatology Research

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