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The new science behind the health benefits of caffeine

A study reveals caffeine's potential to enhance heart health by improving endothelial function in systemic lupus erythematosus patients through EPC survival.

9 Oct 2024

Study: People with a sweet tooth at higher risk of developing depression, diabetes, and stroke

People with a preference for sweets are at a higher risk of developing depression, diabetes, and suffering a stroke, according to new research from the University of Surrey.

9 Oct 2024

Advances in technology shed light on cell function

Cells are the basic units of life — but when it comes to cells, if you think basic means simple, think again. Cells are complicated, with many millions of biochemical reactions per second seething within their confines. They also tend to be tiny, so it’s not easy to spy on their operations.

8 Oct 2024

Novel compounds show promise in fighting COVID-19

New research from The Wistar Institute's Salvino lab - led by professor Joseph Salvino, Ph.D. - has identified a novel series of SARS-CoV-2 Mpro inhibitors that may lead to potential new COVID-19 treatments that, according to preclinical testing, effectively inhibits COVID-19 and synergizes with existing anti-COVID therapies.

8 Oct 2024

Breakthrough study reveals Entropic Pulling mechanism of Hsp70 chaperones

Proteins control most of the body's functions, and their malfunction can have severe consequences, such as neurodegenerative diseases or cancer.

8 Oct 2024

Liver X receptor beta offers new hope in treating depression and anxiety

Liver X receptor beta (LXRβ) shows potential in reducing depression and anxiety by improving neurogenesis, reducing neuroinflammation, and enhancing cognitive and emotional function. More research on LXR agonists could reveal new treatments for mental health disorders.

8 Oct 2024

Eating more beans leads to weight loss and better nutrition

Adults who consume beans show higher intake of essential nutrients, better diet quality, and improved weight outcomes, highlighting the health benefits of beans.

8 Oct 2024

Study reveals how morphogens and cell adhesion create sharp tissue boundaries

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, demonstrate how morphogens combined with cell adhesion can generate tissue domains with a sharp boundary in an in vitro model system.

8 Oct 2024

New insights into how DAPK3 regulates the migration of triple-negative breast cancer cells

Triple-negative breast cancer (TNBC) is the subtype of breast cancer that is the hardest to treat. TNBC patients account for more than 20,000 cases of this condition annually in the U.S. alone.

8 Oct 2024

New triple-targeting pharmacological tool developed for cancer treatment

A study led by researchers of the Institute of Biomedicine of the University of Barcelona (IBUB) has developed a new pharmacological tool capable of simultaneously administering three oligonucleotide-based drugs, each acting against a different therapeutic target within the cell.

8 Oct 2024

Replicating Lewy body formation in living neurons to understand Parkinson's disease

Lewy bodies are a hallmark of Parkinson's disease (PD) and other related neurological conditions. Understanding why and how they develop is critical to developing better treatments.

8 Oct 2024

Electro-acupuncture shows promise in obesity management

A team of scientists led by Nanyang Technological University Singapore (NTU Singapore) and Hong Kong University (HKU) has found evidence that electro-acupuncture - a form of traditional Chinese medicine (TCM) treatment - could be used to manage obesity.

8 Oct 2024

Negative impacts of ultra-processed foods pronounced in certain groups

Researchers assesses how lifestyle factors affect the association between health-related quality of life and consumption of ultra-processed food.

8 Oct 2024

Researchers discover effective treatment strategy for lethal glioblastoma

Glioblastoma (GBM) is the most lethal brain tumor, with a median survival rate of merely 12-16 months after diagnosis. Despite surgical, radiation and chemotherapy treatments, the two-year survival rate for GBM patients is less than 10%.

7 Oct 2024

Understanding behavioral changes in early dementia

When most people think of dementia, including Alzheimer's disease, they probably think of memory loss first.

7 Oct 2024

New insights into immune mechanisms that prevent cancer metastasis

Metastatic disease - when cancer spreads from the primary tumor to other parts of the body - is the cause of most cancer deaths.

7 Oct 2024

When CDK12/13 stalls, healthy prostate cells take a malignant turn

CDK12 is established as a tumor suppressor in prostate cancer, with its loss driving aggressive disease and creating vulnerabilities for targeted therapies.

7 Oct 2024

New cell therapy offers effective treatment for patients with T-cell acute lymphoblastic leukemia

A new cell therapy, targeting CD7 on leukaemia cells, gives a potentially effective treatment for patients with T-cell acute lymphoblastic leukaemia (T-ALL) who have exhausted all standard treatment options.

7 Oct 2024

Researchers identify key mechanism behind atherosclerosis in Hutchinson-Gilford progeria syndrome

A team of researchers from the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), the Centro de Investigaciones Biológicas Margarita Salas (CIB-CSIC), and the Instituto de Ciencias de Materiales de Madrid (ICMM-CSIC) has made a significant breakthrough in understanding the underlying causes of cardiovascular disease in patients with Hutchinson-Gilford progeria syndrome (HGPS), an ultra-rare genetic disorder that accelerates the aging process.

7 Oct 2024