covid 19 News and Research

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Study observes virologic rebound in 20% of COVID-19 patients treated with nirmatrelvir-ritonavir

An observational study of patients being treated for acute COVID-19 in a multicenter health care system observed virologic rebound in about 20 percent of patients treated with nirmatrelvir-ritonavir (N-R) versus about 2 percent of those who did not receive treatment. The findings are published in Annals of Internal Medicine.

13 Nov 2023

Study reveals coadministered COVID-19 and flu vaccines effective, especially in seniors

The study in JAMA Network Open evaluates the effectiveness of simultaneously administering the Pfizer-BioNTech BNT162b2 BA.4/5 COVID-19 vaccine and seasonal influenza vaccines versus separate administration. Results suggest similar or slightly increased COVID-19 outcomes and lower influenza-related outcomes with coadministration, particularly in those aged 65 and above.

13 Nov 2023

Automated referrals to pharmacy services dramatically increase appropriate statin prescription rates

The odds of prescribing the appropriate dose of statins - a medicine used to lower "bad" cholesterol levels - increased sixfold when automated referrals were made to pharmacy services, instead of relying on traditional prescribing methods, according to researchers at the Perelman School of Medicine at the University of Pennsylvania.

13 Nov 2023

One in five individuals taking nirmatrelvir-ritonavir therapy found to experience rebound COVID

A new study by investigators from Mass General Brigham found that one in five individuals taking Nirmatrelvir-ritonavir therapy, commonly known as Paxlovid, to treat severe symptoms of COVID-19, experienced a positive test result and shedding of live and potentially contagious virus following an initial recovery and negative test - a phenomenon known as virologic rebound.

13 Nov 2023

Hospital-acquired COVID-19 mortality drops in Omicron era post-vaccination, reveals Swedish study

In a study published in JAMA Network Open, researchers found that hospital-acquired SARS-CoV-2 infections in Stockholm led to increased 30-day mortality in the pre-vaccination period but showed significantly lower mortality during the Omicron wave post-vaccination. The study underscores the importance of vaccination in reducing mortality risks from nosocomial SARS-CoV-2 infections.

13 Nov 2023

Non-invasive device detects Alzheimer's and Parkinson's biomarkers with high accuracy

An international team of researchers has developed a handheld, non-invasive device that can detect biomarkers for Alzheimer's and Parkinson's Diseases.

13 Nov 2023

Study reveals no neuroinflammation in long COVID patients with neuropsychiatric symptoms

In a JAMA Network Open study, researchers found no evidence of neuroinflammation or blood-brain barrier dysfunction in cerebrospinal fluid markers of individuals with post-COVID-19 condition and neuropsychiatric symptoms compared to controls. The study, which assessed cytokines, chemokines, and neuroinflammation markers, suggests that persistent central nervous system immune activation may not be the primary driver of neurological long COVID symptoms.

13 Nov 2023

Study uncovers how COVID-19 pandemic created new social disparities and affected existing inequalities

An article by Stockholm University researchers was recently published in the Proceedings of the National Academy of Sciences (PNAS).

13 Nov 2023

Study sheds light on role of antibodies in vaccine protection against COVID-19 variants

Efforts to contain the Covid-19 pandemic have largely focused on vaccine development and deployment. But how exactly do our immune systems respond to COVID-19 vaccines?

13 Nov 2023

How lawmakers in Texas and Florida undermine covid vaccination efforts

Katherine Wells wants to urge her Lubbock, Texas, community to get vaccinated against covid-19. "That could really save people from severe illness," said Wells, the city's public health director.

13 Nov 2023

How chronic stress and mood disorders affect adolescent brain development

Advanced brain imaging techniques reveal how adolescent brain development influences, and is influenced by, factors including chronic stress and mood disorders.

13 Nov 2023

Revolutionizing critical care: the potential of gut microbiota therapeutics

The curative potential and limitations of gut microbiome-based therapeutics in critical illnesses.

13 Nov 2023

Willow bark may be the source of a new antiviral drug

Scientists have found that specially processed samples of willow bark extract have an antiviral effect which isn’t seen in already known medical compounds from willow bark, such as salicylic acid, the precursor to modern aspirin.

13 Nov 2023

New hope for TB patients as UNITE4TB launches clinical trial program

Today, UNITE4TB, an international public-private partnership striving to fast-track the development of innovative Tuberculosis (TB) treatments, announced the start of its phase 2B/C clinical trial program with the first participant enrolled at its trial site in Cape Town, South Africa.

13 Nov 2023

MHRA and partners celebrate 10th anniversary of the International Coalition of Medicines Regulatory Authorities

As a founding member and former chair of the International Coalition of Medicines Regulatory Authorities (ICMRA), the Medicines and Healthcare products Regulatory Agency (MHRA) is joining global partners in celebrating ten years of strategic leadership and cooperation.

13 Nov 2023

Open-science triumph: Crowdsourced initiative yields potent SARS-CoV-2 antivirals

In this study, researchers harnessed crowdsourcing and open science to develop new antivirals against SARS-CoV-2, focusing on its main protease, Mpro. Their approach led to the discovery of potent compounds, including one with high efficacy in cell lines and cross-reactivity against various COVID-19 variants, demonstrating the potential of collaborative and transparent drug discovery in tackling global health crises.

12 Nov 2023

US reporting system to detect vaccine safety issues may not be meeting its own standards

A US reporting system designed to detect potential safety issues with vaccines is supposed to be user-friendly, responsive, and transparent.

10 Nov 2023

Minnesota data-sharing model tracks drug overdose hospital and ED trends

In a recently released study, researchers at Hennepin Healthcare and other Minnesota health systems describe how a COVID-19 collaboration across Minnesota health systems was adapted to monitor near-real-time trends in substance use–related hospital and emergency department (ED) visits.

10 Nov 2023

New study raises questions about the benefits of pet ownership

There is a general understanding that pets have a positive impact on one's well-being. A new study by Michigan State University found that although pet owners reported pets improving their lives, there was not a reliable association between pet ownership and well-being during the COVID-19 pandemic.

10 Nov 2023

Study narrows down potential causes of Long COVID brain fog and other neuropsychiatric symptoms

Neuropsychiatric symptoms of Long COVID, including brain fog, inability to concentrate, and headache, have puzzled researchers and clinicians, who are hunting for those symptoms' causes.

10 Nov 2023

covid 19 News and Research

Study observes virologic rebound in 20% of COVID-19 patients treated with nirmatrelvir-ritonavir

Study reveals coadministered COVID-19 and flu vaccines effective, especially in seniors

Automated referrals to pharmacy services dramatically increase appropriate statin prescription rates

One in five individuals taking nirmatrelvir-ritonavir therapy found to experience rebound COVID

Hospital-acquired COVID-19 mortality drops in Omicron era post-vaccination, reveals Swedish study

Non-invasive device detects Alzheimer's and Parkinson's biomarkers with high accuracy

Study reveals no neuroinflammation in long COVID patients with neuropsychiatric symptoms

Study uncovers how COVID-19 pandemic created new social disparities and affected existing inequalities

Study sheds light on role of antibodies in vaccine protection against COVID-19 variants

How lawmakers in Texas and Florida undermine covid vaccination efforts

How chronic stress and mood disorders affect adolescent brain development

Revolutionizing critical care: the potential of gut microbiota therapeutics

Willow bark may be the source of a new antiviral drug

New hope for TB patients as UNITE4TB launches clinical trial program

MHRA and partners celebrate 10th anniversary of the International Coalition of Medicines Regulatory Authorities

Open-science triumph: Crowdsourced initiative yields potent SARS-CoV-2 antivirals

US reporting system to detect vaccine safety issues may not be meeting its own standards

Minnesota data-sharing model tracks drug overdose hospital and ED trends

New study raises questions about the benefits of pet ownership

Study narrows down potential causes of Long COVID brain fog and other neuropsychiatric symptoms

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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