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Scientists develop indices that provide information about prognosis of cancers

Researchers from the School of Medicine in Ribeirão Preto, at the University of São Paulo, in collaboration with international groups, have developed indices that provide information about the prognosis of cancers, aid in the choice of the most appropriate therapy to be used and identify potential targets for the development of new drugs.

6 Apr 2018

Largest genomic analysis supports additional classification of tumors

University of North Carolina Lineberger Comprehensive Cancer Center researchers are reporting the concluding findings from a major analysis of nearly 10,000 different tumor samples that focused on identifying similarities between cancers based on changes in their genes, and the way their genes are expressed.

6 Apr 2018

Johns Hopkins scientist calls for more integration of epigenetics and genetics research

In a review article published April 5 in the New England Journal of Medicine, scientist Andrew Feinberg, M.D., calls for more integration between two fields of DNA-based research: genetics and epigenetics.

6 Apr 2018

Scientists identify key genetic events responsible for initiating childhood leukemia

The key genetic events responsible for initiating the early stages of a type of childhood leukemia have been identified by scientists at The Institute of Cancer Research, London. Insights into the ‘founder’ genetic mutation for this type of leukemia, present in all the cancer cells, could be used in the development of new targeted drugs.

6 Apr 2018

Agilent and BioTek announce new integrated metabolic analysis and imaging solution

Agilent Technologies Inc. and BioTek Instruments, Inc., today announced a new, integrated solution that combines cellular metabolic analysis and imaging technologies.

From Agilent Technologies 6 Apr 2018

Batteries must cope with growing European wearable medical device market

With Europe’s wearable medical device market expected to more than double its 2015 value by 2020, it is critical that medical original equipment manufacturers (OEMs) are launching products that are safe, reliable and effective.

6 Apr 2018

Waking up “sleeping” stem cells in the brain could improve its ability to repair injury

Researchers have identified a new type of stem cell that could boost the brain’s ability to repair damage caused by brain injury or disease.

6 Apr 2018

Scientists create organoids that could help guide bladder cancer treatment

Researchers have created patient-specific bladder cancer organoids that imitate many of the features of real tumors and may therefore be used to study how cancer evolves.

6 Apr 2018

New comprehensive analysis of breast and gynecological cancers

A large amount of information has been gathered by researchers from University of Texas MD Anderson Cancer Center who were studying the molecular features of tumors and their subtypes. They were working on breast and four types of gynaecological cancers.

6 Apr 2018

New brain cells are added in elderly adult brains too

Scientists have long debated the fact that brains change with age and no new brain cells or neurons are added once an adult is fully grown. With age the number of neurons begins to decline leading to several problems with memory and cognition.

6 Apr 2018

Study provides systematic view of gene enhancer activity in diverse tumors

At the heart of any cancer diagnosis or treatment are cells. If one thinks of the cell components controlling gene activation as a Russian nesting-doll of gene regulatory layers, within those increasingly smaller tiers are short pieces of non-coding DNA called enhancers.

5 Apr 2018

New method simplifies genetic modification of T-cells in mice

A new method enables genes in living T-cells in mice to be modified quickly and efficiently. It makes use of plasmids, a tried-and-tested method of genetic engineering.

5 Apr 2018

Researchers discover potential new therapeutic target for Ewing sarcoma

The sarcoma research group of the Bellvitge Biomedical Research Institute, led by Dr. Òscar Martínez-Tirado, has identified a potential new therapeutic target for Ewing sarcoma, the second most frequent bone cancer in children and adolescents, and a tumor known by its aggressiveness and tendency to metastasize.

5 Apr 2018

Autofluorescence imaging evaluates cell metabolism and wound healing

Kyle Quinn, assistant professor of biomedical engineering at the University of Arkansas, has published a review highlighting recent advances in autofluorescence imaging and discussing its role in evaluating cell metabolism.

5 Apr 2018

Researchers identify macrophage populations involved in development of atherosclerosis

Stroke and heart attack are the leading cause of death in the Western world. Würzburg scientists have used a special technique to get a clearer picture of the cells involved and their activity.

5 Apr 2018

Free Radical Formation in Electronic Cigarette Aerosols

An interview with Prof. John Richie, describing his presentation at Pittcon 2018 on free radical formation in electronic cigarette aerosols.

From Pittcon 5 Apr 2018

Researchers suggest a theory for the evolution of HIV from SIV

A new study has shed light on how HIV may have evolved from the simian immunodeficiency virus (SIV) that originated in non-human primates.

5 Apr 2018

Researchers create adult-like cardiac model by introducing early stimulation

Researchers are now able to use induced pluripotent stem cells to form a model of human adult-like cardiac muscle by introducing electric and mechanical stimulation at an early stage. Since this muscle is similar to the adult heart, it could serve as a better model for testing the effects of drugs and toxic substances than current tissue engineered heart models.

5 Apr 2018

Study shows new health benefits in berry pigment

Naturally occurring pigments in berries, also known as anthocyanins, increase the function of the sirtuin 6 enzyme in cancer cells, a new study from the University of Eastern Finland shows. The regulation of this enzyme could open up new avenues for cancer treatment. The findings were published in Scientific Reports.

5 Apr 2018