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People with type 2 diabetes have epigenetic changes on DNA

People with type 2 diabetes have epigenetic changes on their DNA that healthy individuals do not have. This has been shown in a major study by researchers at Lund University. The researchers also found epigenetic changes in a large number of genes that contribute to reduced insulin production.

9 Mar 2014

Dr. Daniel D. Von Hoff named one of ASCO's 50 Oncology Luminaries

In association with its 50th anniversary, the American Society of Clinical Oncology has named Dr. Daniel D. Von Hoff one of ASCO's 50 Oncology Luminaries, celebrating 50 doctors who over the past half-century have significantly advanced cancer care.

9 Mar 2014

FDA-approved anti-psychotic drugs possess tumor-killing activity against glioblastoma

Researchers at the University of California, San Diego School of Medicine have discovered that FDA-approved anti-psychotic drugs possess tumor-killing activity against the most aggressive form of primary brain cancer, glioblastoma. The finding was published in this week's online edition of Oncotarget.

8 Mar 2014

Teva launches generic Xeloda Tablets in the U.S.

Teva Pharmaceutical Industries Ltd. announces the launch of the generic equivalent to Xeloda (Capecitabine) Tablets, 150 MG and 500 MG, in the United States. Xeloda is marketed by Genentech in the United States.

8 Mar 2014

Longtime allies team up to create Penn Medicine/CHOP Friedreich's Ataxia Center of Excellence

Three longtime allies have joined forces to create the new Penn Medicine/CHOP Friedreich's Ataxia Center of Excellence.

7 Mar 2014

Warmer temperatures allow malaria to spread to higher elevations

Malaria, a mosquito-borne disease, infects more than 300 million people each year. Cooler highland regions have historically provided havens from malaria, but it has been predicted that the disease could be especially sensitive to climate change, since both the Plasmodium parasites that cause it and the Anopheles mosquitoes that spread it thrive at warm temperatures. The potential impact of global warming on the worldwide incidence of malaria has been debated for more than two decades.

7 Mar 2014

TAZ gene represents potential target for drug therapies to treat aggressive types of breast cancer

Significance: Understanding more about how the different types of cells in breast tissue develop improves our knowledge of breast cancer. TAZ represents a potential new target for drug therapies to treat aggressive types of breast cancer.

7 Mar 2014

Incyte Corporation publishes results of Phase III trial of ruxolitinib in patients with polycythemia vera

Incyte Corporation (Nasdaq: INCY) today announced that a pivotal Phase III trial of ruxolitinib compared to best available therapy in patients with polycythemia vera who are resistant to or intolerant of hydroxyurea has met its primary endpoint of achieving phlebotomy independence and reducing spleen size by 35 percent or more.

7 Mar 2014

Researchers identify communication strategies aimed at creating risk perceptions about generic drugs

Although there is widespread consensus among the scientific community that the composition of generic drugs is identical to that of brand name drugs, this is not the case among the public.

7 Mar 2014

Researchers examine association between diabetes and obesity

It's by now well established that obesity is a major risk factor for diabetes. But what exactly is it about extra body fat that leads to insulin resistance and blood glucose elevation, the hallmarks of diabetes?

7 Mar 2014

Scientists identify important step toward shutting down growth of prostate cancer cells

Scientists at UT Southwestern Medical Center have identified an important step toward potentially shutting down the growth of prostate cancer cells.

7 Mar 2014

Prescriptions for benzodiazepines with opioid analgesics may lead to medication-related deaths

Prescriptions for benzodiazepines are rising in primary care, and their frequent combined use with opioid analgesics may be contributing to medication-related deaths, a finding that goes largely unreported, according to Stanford researchers.

7 Mar 2014

New method of protecting women from transmission of HIV is safe

Findings of an early phase clinical trial at the University of Alabama at Birmingham suggest that a possible new method of protecting women from the transmission of HIV is safe.

7 Mar 2014

Arizona sued over abortion restrictions

Abortion providers filed suit Wednesday to block new state regulations that limit the use of the most common abortion drugs. Meanwhile, two more Texas abortion clinics are closed as a result of that state's restrictions, bringing total closures to 12.

7 Mar 2014

Research: Expanded smoking cessation benefits should give more people opportunity to quit

People on Medicaid in the U.S. are 68 percent more likely to smoke than the general population. New research in the American Journal of Preventive Medicine suggests that expanded smoking cessation benefits offered under the Affordable Care Act (ACA) should give more people the opportunity to quit.

7 Mar 2014

Ohr Pharmaceutical partners with CSHL to develop trodusquemine and related analogs

Ohr Pharmaceutical, a pharmaceutical company focused on the development of novel therapeutics for large unmet medical needs, and leading global cancer research center Cold Spring Harbor Laboratory (CSHL) today announced the establishment of DepYmed Inc., a new joint venture to develop trodusquemine and related analogs.

6 Mar 2014

Study shows how changes in organized cell membrane network of heart muscle leads to heart failure

Colchicine, a drug that's used to treat gout, has the beneficial side effect of lowering the risk of heart attack in patients taking it. Conversely, taxol, a drug for treating cancer, has the opposite effect; raising the risk of heart failure.

6 Mar 2014

Alkermes initiates pivotal clinical development program for treatment of MDD

Alkermes plc today announced the initiation of the pivotal clinical development program for ALKS 5461, a once-daily, oral investigational medicine with a novel mechanism of action for the adjunctive treatment of major depressive disorder (MDD).

6 Mar 2014

First Edition: March 6, 2014

Today's headlines include reports about health law rule changes announced yesterday by the Obama administration.

6 Mar 2014

Safeguard Scientifics reports net income of $24 million for fourth quarter 2013

Safeguard Scientifics, Inc. today announced fourth quarter and full-year 2013 financial results. For the three months ended December 31, 2013, Safeguard's net income was $24.0 million, or $1.10 per share, compared to net loss of $10.8 million, or $0.51 per share for the same period in 2012. For the year ended December 31, 2013, Safeguard's net loss was $35.5 million, or $1.66 per share, compared to $39.4 million, or $1.88 per share for the same period in 2012.

6 Mar 2014

Drugs News and Research

People with type 2 diabetes have epigenetic changes on DNA

Dr. Daniel D. Von Hoff named one of ASCO's 50 Oncology Luminaries

FDA-approved anti-psychotic drugs possess tumor-killing activity against glioblastoma

Teva launches generic Xeloda Tablets in the U.S.

Longtime allies team up to create Penn Medicine/CHOP Friedreich's Ataxia Center of Excellence

Warmer temperatures allow malaria to spread to higher elevations

TAZ gene represents potential target for drug therapies to treat aggressive types of breast cancer

Incyte Corporation publishes results of Phase III trial of ruxolitinib in patients with polycythemia vera

Researchers identify communication strategies aimed at creating risk perceptions about generic drugs

Researchers examine association between diabetes and obesity

Scientists identify important step toward shutting down growth of prostate cancer cells

Prescriptions for benzodiazepines with opioid analgesics may lead to medication-related deaths

New method of protecting women from transmission of HIV is safe

Arizona sued over abortion restrictions

Research: Expanded smoking cessation benefits should give more people opportunity to quit

Ohr Pharmaceutical partners with CSHL to develop trodusquemine and related analogs

Study shows how changes in organized cell membrane network of heart muscle leads to heart failure

Alkermes initiates pivotal clinical development program for treatment of MDD

First Edition: March 6, 2014

Safeguard Scientifics reports net income of $24 million for fourth quarter 2013

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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