Genetic News and Research

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Researchers use $1.3M grant from NIH to study on obesity and Type 2 diabetes

A team of Northern Arizona University-led researchers is using nearly $1.3 million in new funding from the National Institutes of Health to continue with the world's longest-running study on obesity and Type 2 diabetes.

15 Feb 2010

SRC-3 gene sends signal to cell membrane to promote cell motility

The master gene called SRC-3 (steroid receptor coactivator 3) not only enhances estrogen-dependent growth of cancer cells by activating and encouraging the transcription of a genetic message into a protein, it also sends a signal to the cell membrane to promote cell motility or movement - a key element of cancer spread or metastasis, said Baylor College of Medicine (www.bcm.edu) researchers and collaborators in a report that appears in the current issue of the journal Molecular Cell.

15 Feb 2010

Plagiocephaly babies need to be screened and monitored early in life for possible cognitive, motor delays

In a new study, infants averaging six months of age who exhibited positional plagiocephaly (flat head syndrome) had lower scores than typical infants in observational tests used to evaluate cognitive and motor development. Positional or deformational plagiocephaly may occur when external forces shape an infant's skull while it is still soft and malleable, such as extended time spent lying on a hard surface or in one position. This is the first controlled study to suggest that babies who have flattened areas on the back of their heads during the first year of life may be at risk for developmental delay.

15 Feb 2010

Hypnosis has potential therapeutic value in children with respiratory disorders

Hypnosis has potential therapeutic value in children with respiratory disorders for alleviating symptoms such as habit cough or unexplained sensations of difficulty breathing and for lessening a child's discomfort during medical procedures.

15 Feb 2010

Symposium exploring future of cancer research to be hosted at GUMC

The Georgetown Lombardi Comprehensive Cancer Center hosts a symposium exploring the future of cancer research on Feb. 17th at Georgetown University Medical Center. Sponsored by the Ruesch Center for the Cure of Gastrointestinal Cancers, the two-part symposium, "Fighting a Smarter War Against Cancer: Personalized Medicine & the Cure for Cancer," will offer a focus on personalized medicine by bringing together experts in academia, industry and advocacy.

15 Feb 2010

New research finds sensory cortex develops late in fragile X syndrome defect

Why do people with fragile X syndrome, a genetic defect that is the best-known cause of autism and inherited mental retardation, recoil from hugs and physical touch - even from their parents?

12 Feb 2010

VR technology plays important role in treating patients with PTSD

Posttraumatic stress disorder (PTSD) threatens to overload healthcare and social support systems worldwide as the number of cases rises and existing treatments are not sufficiently effective.

12 Feb 2010

HIV transmission among male partners: CFAR scientists discover origin of strains

A team of scientists, led by a virologist from the University of California, San Diego's Center for AID Research (CFAR), has discovered the origin of strains of human immunodeficiency virus (HIV) among men who have sex with men. The study, which may be important in developing prevention strategies for HIV, will appear in Science Translational Medicine on February 10, 2010.

12 Feb 2010

Histone modifications associated with pancreatic cancer development and progression

Specific chemical modifications to proteins called histones, which are found in the nucleus of cells and act as spools around which DNA is wound, can be used to predict prognosis and response to treatment in subsets patients with pancreatic cancer, a study by researchers at UCLA's Jonsson Comprehensive Cancer Center has found.

12 Feb 2010

Better and standardized animal models needed for musculoskeletal regenerative medicine

Clinical testing and development of novel therapies based on advances in tissue engineering and regenerative medicine that will one day enable the repair and replacement of diseased or damaged human muscle, bone, tendons, and ligaments depends on the availability of good animal models.

12 Feb 2010

Also in Global Health News: China's health care system; Breastfeeding practices in Pakistan; HIV transmission in MSM; Abu Dhabi joins malaria fight

The Los Angeles Times examines China's transition to "Western-style privatized medicine" through the government's "$124-billion overhaul, chiefly to improve service in rural areas." The article details the efforts of a woman from Inner Mongolia to get care in Beijing for her ailing father and looks at climbing health care costs and the growing "black market for medical care" (Pierson, 2/11).

12 Feb 2010

CapitalBio officially joins Roche NimbleGen CSP Program

Roche NimbleGen announced today that Beijing-based genomic services provider CapitalBio has officially joined the Roche NimbleGen Certified Service Provider (CSP) Program.

12 Feb 2010

ASU scientists develop versatile DNA reader to unlock DNA genetic code

Arizona State University scientists have come up with a new twist in their efforts to develop a faster and cheaper way to read the DNA genetic code. They have developed the first, versatile DNA reader that can discriminate between DNA's four core chemical components⎯the key to unlocking the vital code behind human heredity and health.

12 Feb 2010

Cancer drug could be effective for treating recurrent nose bleeds

Patients suffering from hereditary hemorrhagic telangiectasia (HHT), an inherited vascular condition characterized by profuse nosebleeds, may find hope in a cancer-fighting drug called bevacizumab, also known as Avastin.

12 Feb 2010

Therapeutic cell types obtained from iPS cells demonstrate abnormal expansion and early cellular aging

Advanced Cell Technology, Inc. or “ACT” reported that a range of therapeutic cell types obtained from induced pluripotent stem (iPS) cells exhibit abnormal expansion and early cellular aging. The research, which appears online (published-ahead-of- print) in the journal STEM CELLS by ACT and its collaborators at Stem International (SCRMI), Harvard Medical School, and the University of Illinois, compares a variety of replacement cell types derived from human iPS cells with their embryonic stem (ES) cell counterparts. The findings support the use of ACT’s single blastomere-derived human embryonic stem cell lines which do not display early aging.

12 Feb 2010

FKF receives funds to launch Fragile Kids Partner Program

The Centene Foundation for Quality Healthcare announced today that it has awarded a $35,000 grant to Fragile Kids Foundation, Inc. (FKF), a nonprofit organization based in Atlanta, Ga.

12 Feb 2010

Critical phases of brain development may be mistimed in autistic patients, says study

Research into Fragile X Syndrome - a genetic condition that is the leading known cause of autism - has discovered that critical phases in the brain's development may be mistimed in people with the condition.

11 Feb 2010

Chemical compound found in blood shows promise in preventing intractable form of heart failure

A chemical compound found normally in the blood has shown promise in treating and preventing an intractable form of heart failure in a mouse model of the disease, report researchers at the University of Illinois at Chicago College of Medicine.

11 Feb 2010

Neurotoxin study may help find new therapies to block hyperactive ion channels

There are approximately 500 species of cone snails, each producing 50 - 200 different conotoxins. A similar number of peptide toxins are produced by snakes, spiders, sea anemones, scorpions and other venomous animals. The animals use the neurotoxins to paralyze their prey.

11 Feb 2010

New genetic 'hotspots' may help doctors devise therapies for bowel cancer patients

Cancer Research UK scientists have identified the frequency of new genetic 'hotspots' which could help doctors to tailor therapies to as many as 3,000 additional bowel cancer patients each year, according to research published in the British Journal of Cancer today.

11 Feb 2010

Genetic News and Research

Researchers use $1.3M grant from NIH to study on obesity and Type 2 diabetes

SRC-3 gene sends signal to cell membrane to promote cell motility

Plagiocephaly babies need to be screened and monitored early in life for possible cognitive, motor delays

Hypnosis has potential therapeutic value in children with respiratory disorders

Symposium exploring future of cancer research to be hosted at GUMC

New research finds sensory cortex develops late in fragile X syndrome defect

VR technology plays important role in treating patients with PTSD

HIV transmission among male partners: CFAR scientists discover origin of strains

Histone modifications associated with pancreatic cancer development and progression

Better and standardized animal models needed for musculoskeletal regenerative medicine

Also in Global Health News: China's health care system; Breastfeeding practices in Pakistan; HIV transmission in MSM; Abu Dhabi joins malaria fight

CapitalBio officially joins Roche NimbleGen CSP Program

ASU scientists develop versatile DNA reader to unlock DNA genetic code

Cancer drug could be effective for treating recurrent nose bleeds

Therapeutic cell types obtained from iPS cells demonstrate abnormal expansion and early cellular aging

FKF receives funds to launch Fragile Kids Partner Program

Critical phases of brain development may be mistimed in autistic patients, says study

Chemical compound found in blood shows promise in preventing intractable form of heart failure

Neurotoxin study may help find new therapies to block hyperactive ion channels

New genetic 'hotspots' may help doctors devise therapies for bowel cancer patients

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