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Scientists open door to development of new drugs to combat osteoporosis

Scientists from the University of Granada (UGR) have opened the door to the development of new drugs against osteoporosis, one of the most common chronic illnesses in the world, especially among women 65 or over.

6 Mar 2014

Researchers identify high-speed cellular transport mechanism

Our DNA and its architecture are duplicated every time our cells divide. Histone proteins are key building blocks of this architecture and contain crucial information that regulates our genes. Danish researchers show how an enzyme controls reliable and high-speed delivery of histones to DNA copying hubs in our cells. This shuttling mechanism is crucial to maintain normal function of our genes and prevent disease. The results are published in the journal Nature Communications.

6 Mar 2014

Costs for medications expected to rise by 3 – 5% in all health care settings in 2014

Costs for medications are expected to rise by three to five percent in all health care settings in 2014, according to a report published online ahead of print, by the American Journal of Health-System Pharmacy (AJHP), the professional journal of the American Society of Health-System Pharmacists (ASHP).

6 Mar 2014

Debiopharm plans to expand, optimize activities at Martigny manufacturing facility

Debiopharm Group, a Swiss-based global biopharmaceutical group of companies active in drug development, GMP manufacturing of proprietary drugs, diagnostics, and investments, has announced its decision to expand and optimize activities at Debiopharm Research & Manufacturing S.A., its industrial development and production facility in Martigny (Valais, Switzerland), through acquisition of industrial high-value added activities or companies in the pharmaceutical, biotech or medtech field.

6 Mar 2014

New drug is effective against superbug MRSA

"I routinely call hospitals and request their yearly antibiotic susceptibility testing data," said Washington University in St. Louis' Timothy Wencewicz. "The log might say, for example, that they've treated hundreds of patients for Acinetobacter baumanni, a bacterium brought into U.S. hospitals by soldiers wounded in the Iraq war, with 30 different antibiotics.

6 Mar 2014

Scientists reveal how a genetic code variation results in devastating brain diseases

New findings reveal how a mutation, a change in the genetic code that causes neurodegeneration, alters the shape of DNA, making cells more vulnerable to stress and more likely to die.

6 Mar 2014

New bioinspired gel material could help repair damaged teeth and bone

A bit of pressure from a new shrinking, sponge-like gel is all it takes to turn transplanted unspecialized cells into cells that lay down minerals and begin to form teeth.

6 Mar 2014

President Obama's budget: Medicare means testing and lower drug costs

The budget proposal includes a provision to make wealthier seniors in Medicare pay more as well and another to try to drive down the cost of prescription drugs. A rival Republican plan is also expected to propose cuts to Medicare and Medicaid.

6 Mar 2014

Prehospital stroke alerts can shorten time to emergency treatment

Prehospital stroke alerts by emergency medical services (EMS) personnel can shorten the time to effective treatment with "clot-busting" drugs for patients with stroke, according to a report in the March issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

6 Mar 2014

Study to understand role of bacterium in heart valve disease

A disease-causing bacterium found in the mouth needs manganese, a trace mineral, in order to cause a serious heart infection, according to a preclinical study led by researchers at Virginia Commonwealth University Philips Institute for Oral Health Research in the School of Dentistry.

6 Mar 2014

Specific protein has vital role in controlling symptoms of allergic asthma, say researchers

An enzyme that helps maintain immune system function by "throwing away" a specific protein has a vital role in controlling symptoms of allergic asthma, new research in mice suggests.

6 Mar 2014

Research shows how patient experiences can be used to improve healthcare

A research project led by Oxford University is showing how patient experiences can be used to improve healthcare - not through targets and surveys, but by getting doctors, nurses and patients talking together about care on the ward.

6 Mar 2014

Verastem presents preliminary data from VS-6063 Phase 1 trial in Japanese patients with solid tumors

Verastem, Inc., focused on discovering and developing drugs to treat cancer by the targeted killing of cancer stem cells, today presented preliminary data from an ongoing First-in-Asia Phase 1 trial of VS-6063 in Japanese patients with advanced solid tumors, including one patient with mesothelioma. The Phase 1 study assessed the safety and pharmacokinetics of single agent VS-6063.

5 Mar 2014

Curie-Cancer, DNA Therapeutics renew partnership to identify new class of cancer drugs

Curie-Cancer, the body responsible for developing Institut Curie’s industry partnership activities, and DNA Therapeutics, a biopharmaceutical company that is developing a new class of cancer drugs, are renewing their partnership.

5 Mar 2014

First Edition: March 5, 2014

Today's headlines include reports about President Barack Obama's 2015 budget as well as the latest state-level Medicaid expansion developments.

5 Mar 2014

Research shows depletion of cholesteryl ester impairs prostate cancer aggressiveness

Researchers have discovered a link between prostate cancer aggressiveness and the accumulation of a compound produced when cholesterol is metabolized in cells, findings that could bring new diagnostic and treatment methods.

5 Mar 2014

New study shows male hormones play important role; may enhance IVF therapy in women

Several fertility clinics across the country are beginning to administer testosterone, either through a patch or a gel on the skin, to increase the number of eggs produced by certain women undergoing in vitro fertilization (IVF).

5 Mar 2014

Stock-outs of ARV drugs in Central African Republic impact health of HIV-infected people

According to Pierre-Marie David of the University of Montreal's Faculty of Pharmacy, stock-outs of antiretroviral (ARV) drugs in recent years in the Central African Republic have had a dramatic impact on the health of HIV-infected people.

5 Mar 2014

Small-molecule drug effective in protecting nonhuman primates from lethal Marburg virus

For the first time, scientists have demonstrated the effectiveness of a small-molecule drug in protecting nonhuman primates from the lethal Marburg virus. Their work, published online in the journal Nature, is the result of a continuing collaboration between Army scientists and industry partners that also shows promise for treating a broad range of other viral diseases.

5 Mar 2014

Researchers identify high levels of certain protein in brains of people suffering from essential tremor

A team of researchers from Universit- Laval and CHU de Qu-bec identified unusually high levels of a certain protein in the brains of people suffering from essential tremor (ET), a movement disorder that affects 4% of the adult population.

5 Mar 2014

Drugs News and Research

Scientists open door to development of new drugs to combat osteoporosis

Researchers identify high-speed cellular transport mechanism

Costs for medications expected to rise by 3 – 5% in all health care settings in 2014

Debiopharm plans to expand, optimize activities at Martigny manufacturing facility

New drug is effective against superbug MRSA

Scientists reveal how a genetic code variation results in devastating brain diseases

New bioinspired gel material could help repair damaged teeth and bone

President Obama's budget: Medicare means testing and lower drug costs

Prehospital stroke alerts can shorten time to emergency treatment

Study to understand role of bacterium in heart valve disease

Specific protein has vital role in controlling symptoms of allergic asthma, say researchers

Research shows how patient experiences can be used to improve healthcare

Verastem presents preliminary data from VS-6063 Phase 1 trial in Japanese patients with solid tumors

Curie-Cancer, DNA Therapeutics renew partnership to identify new class of cancer drugs

First Edition: March 5, 2014

Research shows depletion of cholesteryl ester impairs prostate cancer aggressiveness

New study shows male hormones play important role; may enhance IVF therapy in women

Stock-outs of ARV drugs in Central African Republic impact health of HIV-infected people

Small-molecule drug effective in protecting nonhuman primates from lethal Marburg virus

Researchers identify high levels of certain protein in brains of people suffering from essential tremor

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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