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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Two research groups present data on Pressure BioSciences' PCT Platform at HUPO 2012

Pressure BioSciences, Inc. today announced that scientists from two separate research groups presented data at the recent HUPO 11th Annual World Congress (Boston, MA) indicating that the incorporation of the Company's Pressure Cycling Technology Platform into their sample preparation processes resulted in a marked improvement in the quality and/or efficiency of test results.

3 Nov 2012

Weill Cornell researchers awarded Grand Challenges Explorations grants

Weill Cornell Medical College announced today that it is a Grand Challenges Explorations winner, an initiative funded by the Bill & Melinda Gates Foundation.

3 Nov 2012

Data from four Phase 2 trials of AMG 145 to be presented at AHA Scientific Sessions 2012

Amgen will present data from four Phase 2 trials of AMG 145, an investigational fully human monoclonal antibody directed against PCSK9, a protein that reduces the liver's ability to remove low density lipoprotein cholesterol, or "bad" cholesterol from the blood, at the upcoming American Heart Association Scientific Sessions 2012.

3 Nov 2012

Bristol-Myers Squibb, Pfizer and Portola partner to conduct clinical study of PRT4445 and ELIQUIS

Portola Pharmaceuticals, Inc., Bristol-Myers Squibb Company and Pfizer Inc. today announced a clinical collaboration agreement to conduct a proof-of-concept study of PRT4445 and the investigational oral Factor Xa inhibitor ELIQUIS (apixaban).

3 Nov 2012

Lomitapide shows promise in treating homozygous familial hypercholesterolemia

An international effort led by researchers at the Perelman School of Medicine at the University of Pennsylvania has resulted in positive phase 3 clinical trial results for a new medicine to treat patients suffering from a rare and deadly cholesterol disorder.

3 Nov 2012

Researchers develop new technique to predict enzymes known to accelerate diseases

Predicting how atherosclerosis, osteoporosis or cancer will progress or respond to drugs in individual patients is difficult.

3 Nov 2012

Malaysia hopes to solve nutrition transition problem

With health problems like obesity and diabetes on the rise due to changing diets in emerging economies, Malaysia is forging new linkages between domestic and international scientists and institutions in hopes of mitigating the problem.

3 Nov 2012

Improving health can be as easy as opening freezer door, says Loyola physician

Improving health can be as easy as opening the freezer door. "Save time, save money, boost nutrition and control portions by eating low-calorie, frozen foods," advises Jessica Bartfield, MD, internal medicine who specializes in nutrition and weight management at Loyola University Health System.

3 Nov 2012

Studies show standardizing computer programs help improve genetic testing for Lynch Syndrome

Many patients who have genetic testing for Lynch syndrome, a hereditary predisposition to colon cancer, receive the inconclusive result "variants of uncertain clinical significance."

3 Nov 2012

Physicists to bring to market new drug-discovery tool using genetic sequencing

Today physicists at Wake Forest University and NanoMedica, their biotechnology company partner, received a $700,000 grant from the National Institutes of Health to bring to market a new drug-discovery tool using next-generation genetic sequencing.

3 Nov 2012

Scientists identify biomarker associated with tamoxifen resistance in women with breast cancer

Scientists have identified a molecular 'flag' in women with breast cancer who do not respond or have become resistant to the hormone drug tamoxifen.

From The University of Manchester 3 Nov 2012

CD22 protein could prove to be important new target for anti-cancer therapy

A team of UC Davis investigators has discovered a protein on the surface of lung cancer cells that could prove to be an important new target for anti-cancer therapy. A series of experiments in mice with lung cancer showed that specific targeting of the protein with monoclonal antibodies reduced the size of tumors, lowered the occurrence of metastases and substantially lengthened survival time.

2 Nov 2012

Researchers unlock complex cellular mechanics that instruct glial progenitor cells to divide

In a new study appearing this month in the Journal of Neuroscience, researchers have unlocked the complex cellular mechanics that instruct specific brain cells to continue to divide. This discovery overcomes a significant technical hurdle to potential human stem cell therapies; ensuring that an abundant supply of cells is available to study and ultimately treat people with diseases.

2 Nov 2012

NIH grant increases support of SDSU program that prepares students for doctoral and science careers

Funded by a $2.8 million grant from the National Institutes of Health and the National Institute of General Medical Sciences, the Initiative for Maximizing Student Development supports 30 students studying in the fields of biomedical and behavioral sciences.

2 Nov 2012

Study describes role of TFIIB protein in helping cells repair DNA damage

In a new study, University at Buffalo scientists describe the role that a protein called TFIIB plays in helping cells repair DNA damage, a critical function for preventing the growth of tumors.

2 Nov 2012

Apolipoprotein E plays a major role in maintaining arterial softness

Arterial stiffening has long been considered a major risk factor for cardiovascular disease. Keeping arteries soft and supple might reduce disease risk, but the mechanisms of how arteries stave off hardening has remained elusive.

2 Nov 2012

Study explores impact of IL1β on brain function alterations associated with schizophrenia

There are a growing number of clues that immune and inflammatory mechanisms are important for the biology of schizophrenia. In a new study in Biological Psychiatry, Dr. Mar Fatjó-Vilas and colleagues explored the impact of the interleukin-1β gene (IL1β) on brain function alterations associated with schizophrenia.

2 Nov 2012

Omeros initiates enrollment in OMS824 Phase 1 trial for schizophrenia and Huntington's

Omeros Corporation today announced that the first subject has been enrolled in the Company's Phase 1 clinical trial evaluating OMS824, the lead compound in Omeros' phosphodiesterase 10 (PDE10) program.

1 Nov 2012

Dysfunction in SRGAP3 protein causes developmental brain disorders

A new research discovery has the potential to revolutionize the biological understanding of some childhood psychiatric disorders. Specifically, scientists have found that when a single protein involved in brain development, called "SRGAP3," is malformed, it causes problems in the brain functioning of mice that cause symptoms that are similar to some mental health and neurological disorders in children.

1 Nov 2012

CSHL scientists discover new way to specifically target and kill cancer cells

Cancer cells grow fast. That's an essential characteristic of what makes them cancer cells. They've crashed through all the cell-cycle checkpoints and are continuously growing and dividing, far outstripping our normal cells. To do this they need to speed up their metabolism.

1 Nov 2012

Protein News and Research

Further Reading

Two research groups present data on Pressure BioSciences' PCT Platform at HUPO 2012

Weill Cornell researchers awarded Grand Challenges Explorations grants

Data from four Phase 2 trials of AMG 145 to be presented at AHA Scientific Sessions 2012

Bristol-Myers Squibb, Pfizer and Portola partner to conduct clinical study of PRT4445 and ELIQUIS

Lomitapide shows promise in treating homozygous familial hypercholesterolemia

Researchers develop new technique to predict enzymes known to accelerate diseases

Malaysia hopes to solve nutrition transition problem

Improving health can be as easy as opening freezer door, says Loyola physician

Studies show standardizing computer programs help improve genetic testing for Lynch Syndrome

Physicists to bring to market new drug-discovery tool using genetic sequencing

Scientists identify biomarker associated with tamoxifen resistance in women with breast cancer

CD22 protein could prove to be important new target for anti-cancer therapy

Researchers unlock complex cellular mechanics that instruct glial progenitor cells to divide

NIH grant increases support of SDSU program that prepares students for doctoral and science careers

Study describes role of TFIIB protein in helping cells repair DNA damage

Apolipoprotein E plays a major role in maintaining arterial softness

Study explores impact of IL1β on brain function alterations associated with schizophrenia

Omeros initiates enrollment in OMS824 Phase 1 trial for schizophrenia and Huntington's

Dysfunction in SRGAP3 protein causes developmental brain disorders

CSHL scientists discover new way to specifically target and kill cancer cells

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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