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Researchers discover how muscles regulate oxygen consumption

A new study by researchers from Karolinska Institutet shows that an enzyme called FIH determines how muscles consume oxygen. Without the enzyme, the need for oxygen increases during physical exercise. The finding is of potential significance to elite athletes, who have been found to have higher levels of FIH in their muscles than others.

3 Apr 2018

Human genome is like a time machine, says researcher

The human genome is a bit like a time machine, says Ben Voight, an associate professor in Systems Pharmacology and Translational Therapeutics and of Genetics in Penn's Perelman School of Medicine.

3 Apr 2018

Study reports impact of spaceflight on cardiovascular progenitor cell development and signaling

A new study of the effects of spaceflight on the development of heart cells identified changes in calcium signaling that could be used to develop stem cell-based therapies for cardiac repair.

3 Apr 2018

Scientists develop futuristic gene therapy for liver cancer

Genetically engineered human T cells that are effective at fighting liver cancer in mice may one day help patients fight liver cancer, say researchers.

3 Apr 2018

Stable proteins in the brain offer clues to long-term memory and learning in mice

In the tiny brain space where two nerve cells meet, chemical and electric signals shuttle back and forth, a messaging system that ebbs and flows in those synaptic spaces, sometimes in ways that scientists believe aid and abet learning and memory.

3 Apr 2018

Gut bacteria may hold clues to predict effectiveness of cancer immunotherapies

The composition of bacteria in the gastrointestinal tract may hold clues to help predict which cancer patients are most apt to benefit from the personalized cellular therapies that have shown unprecedented promise in the fight against hard-to-treat cancers, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

3 Apr 2018

Study uncovers mechanism causing chronic GVHD after bone marrow transplant

Allogeneic bone marrow transplant (BMT) is an essential treatment to cure patients with blood cancers such as leukemia. In patients who have undergone chemotherapy and radiation, a small number of cancer cells can remain in the bloodstream and allow the malignancy to recur.

3 Apr 2018

Smart Cells releases first sample of cord blood to treat autism and parents' guide to ASD

Private cord blood company, Smart Cells, has released their 20th sample of stem cells collected from cord blood and tissue to a patient to treat autism. This is the company’s first sample to be released and infused for the condition. This release closely coincides with World Autism Awareness Day on the 2nd April, for which Smart Cells have released a simple informational guide on autism for parents.

3 Apr 2018

Computational biologists develop algorithm to align datasets with single-cell resolution

A team of computational biologists has developed an algorithm that can 'align' multiple sequencing datasets with single-cell resolution.

3 Apr 2018

Researchers identify 200 mutations in non-coding DNA that play role in cancer

Most of the human genome - 98 percent - is made up of DNA but doesn't actually encode genes, the recipes cells use to build proteins.

2 Apr 2018

Iowa State University researcher is searching for new way to fight superbugs

Vincenzo Venditti, an assistant professor of chemistry at Iowa State University, is searching for a new kind of antibiotic in the fight against superbugs.

2 Apr 2018

Combined treatment prolongs survival in mouse models of malignant mesothelioma

Combined treatment with two cancer immunotherapy drugs - one a novel immune modulator and one that focuses and activates the antitumor immune response - significantly prolonged survival in mouse models of the aggressive cancer malignant mesothelioma.

2 Apr 2018

New PET imaging agent could help guide treatments for people with neurological diseases

Researchers have developed a new imaging agent that could help guide and assess treatments for people with various neurological diseases, including Alzheimer's, Parkinson's, and multiple sclerosis.

2 Apr 2018

Scientists identify new function for colon cancer gene

Colon cancer is the second most common cause of cancer-related deaths. The APC protein has long been known for its critical role in preventing colorectal cancer. When APC is inactivated, the development of colorectal cancer is triggered.

2 Apr 2018

Researcher finds that shape of misfolded proteins may contribute to Alzheimer’s, Parkinson’s and Huntington’s disease

Alzheimer's, Parkinson's and Huntington's disease may have more in common than their effects on the functions of the brain and spinal cord. And finding that common thread could lead to a treatment that could work for all three.

2 Apr 2018

Researchers create new compound that appears to activate cancer-fighting T cells

Invariant natural killer T (iNKT) cells are powerful weapons our body's immune systems count on to fight infection and combat diseases like cancer, multiple sclerosis, and lupus. Finding ways to spark these potent cells into action could lead to more effective cancer treatments and vaccines.

2 Apr 2018

Molecular inhibitors found to arrest tumor cell proliferation in lung cancer and mesothelioma

Inhibition of the oncogenic kinase AKT, a key protein governing the cell cycle, was found to arrest cancer cell proliferation and triggered their programmed death by apoptosis.

2 Apr 2018

Researchers unravel immunopathogenesis of Johne's disease

A research team has unraveled the immunopathogenesis of Johne's disease, a chronic bovine disease that has caused endemics in Japan and many other countries, placing financial burdens on cattle farmers.

2 Apr 2018

Study reveals how interneurons emerge and diversify in the brain

Modern neuroscience, for all its complexity, can trace its roots directly to a series of pen-and-paper sketches rendered by Nobel laureate Santiago Ramón y Cajal in the late 19th and early 20th centuries.

31 Mar 2018

Researchers propose a novel tripartite mechanism of neural memory

The overwhelming quest in cognitive science has been (and still is) to scientifically describe mental processes on a molecular level, notably memory and intelligence, and attempt to mimic them technologically. But really 'intelligent' computers can only arise from an appreciation of neural reality with credible principles about the nature of neural mentation.

30 Mar 2018

B Cell News and Research

Researchers discover how muscles regulate oxygen consumption

Human genome is like a time machine, says researcher

Study reports impact of spaceflight on cardiovascular progenitor cell development and signaling

Scientists develop futuristic gene therapy for liver cancer

Stable proteins in the brain offer clues to long-term memory and learning in mice

Gut bacteria may hold clues to predict effectiveness of cancer immunotherapies

Study uncovers mechanism causing chronic GVHD after bone marrow transplant

Smart Cells releases first sample of cord blood to treat autism and parents' guide to ASD

Computational biologists develop algorithm to align datasets with single-cell resolution

Researchers identify 200 mutations in non-coding DNA that play role in cancer

Iowa State University researcher is searching for new way to fight superbugs

Combined treatment prolongs survival in mouse models of malignant mesothelioma

New PET imaging agent could help guide treatments for people with neurological diseases

Scientists identify new function for colon cancer gene

Researcher finds that shape of misfolded proteins may contribute to Alzheimer’s, Parkinson’s and Huntington’s disease

Researchers create new compound that appears to activate cancer-fighting T cells

Molecular inhibitors found to arrest tumor cell proliferation in lung cancer and mesothelioma

Researchers unravel immunopathogenesis of Johne's disease

Study reveals how interneurons emerge and diversify in the brain

Researchers propose a novel tripartite mechanism of neural memory

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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