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Host-cell enzymes vital for inhibiting mutant forms of coronavirus, study finds

Host-cell enzymes called PARP12 and PARP14 are important for inhibiting mutant forms of a coronavirus, according to a study published May 16 in the open-access journal PLOS Pathogens by Stanley Perlman of the University of Iowa, Anthony Fehr of the University of Kansas, and colleagues.

21 May 2019

Ultra-processed diet increases calorie consumption and weight gain

Experts have long suspected that increased consumption of processed foods over the past 50 years has been a primary driver of the obesity epidemic.

21 May 2019

Inhibition of protein may prevent spread of castration-resistant prostate cancer

Researchers at Boston University School of Medicine have discovered that blocking a specific protein, may be a promising strategy to prevent the spread of castration-resistant prostate cancer.

21 May 2019

Small molecule drug could be an effective strategy to treat glioblastoma

A team of researchers have published in the International Journal of Oncology that RITA, a drug able to reactivate the oncosuppressor function of p53, could be an effective strategy to treat glioblastoma.

21 May 2019

Zebrafish may help researchers to use blood stem cells instead of bone marrow transplants

Blood diseases such as leukemia and lymphoma are currently treated with bone marrow transplants -- a transfer of blood stem cells from a healthy person to a patient in need.

21 May 2019

Honey from strawberry trees stops cell proliferation in colon cancer lines

Spanish and Italian researchers have proven that when honey from strawberry trees, a product typical of Mediterranean areas, is added to colon cancer cells grown in the laboratory, cell proliferation is stopped.

21 May 2019

PDIA1 enzyme levels could help diagnose individuals’ predisposition to cardiovascular disease

Measuring the blood plasma levels of an enzyme called PDIA1 could one day become a method of diagnosing a person's predisposition to cardiovascular disease even if they are healthy, i.e., not obese, diabetic or a smoker, and with normal cholesterol.

20 May 2019

Sophisticated molecular machinery is used by dangerous pathogens to infect hosts

Gastric cancer, Q fever, Legionnaires' disease, whooping cough--though the infectious bacteria that cause these dangerous diseases are each different, they all utilize the same molecular machinery to infect human cells.

20 May 2019

First Footage of T-Cells Training To Fight Pathogens Revealed

Immunologists at The University of Texas at Austin have recorded visuals of T-cells learning what kind of cells to ignore when fighting pathogens, to ensure they do not attack healthy cells and tissues when fighting disease. It is the first time that this process has been captured on video.

20 May 2019

Circadian rhythm influences immune responses across a range of diseases

Researchers in Switzerland have conducted a review of studies looking at how circadian rhythm affects the immune response and severity of illnesses ranging from heart attack to allergy.

20 May 2019

Gene linked to rare progressive brain disease causes new kind of congenital disorder

A new kind of congenital disorder caused by a group of mutations in a gene previously linked only to a rare progressive brain disease has been discovered by an international team co-led by Saudi investigators.

20 May 2019

Ultra-Processed foods delay satiety, increase food intake and weight gain

Eating highly processed foods could be associated with weight gain finds a new study. The study was published in the latest issue of Cell Metabolism and is titled, “Ultra-Processed Diets Cause Excess Calorie Intake and Weight Gain: An Inpatient Randomized Controlled Trial of Ad Libitum Food Intake.”

19 May 2019

Researchers map molecular structure and dynamics of one of Alzheimer's stickier culprits

In a new study published in Proceedings of the National Academy of Sciences, researchers from the University of Colorado Denver and Binghamton University are the first to map the molecular structure and dynamics of an aggressive protein modification that spurs on Alzheimer's disease.

18 May 2019

Cell News and Research

Host-cell enzymes vital for inhibiting mutant forms of coronavirus, study finds

Ultra-processed diet increases calorie consumption and weight gain

Inhibition of protein may prevent spread of castration-resistant prostate cancer

Small molecule drug could be an effective strategy to treat glioblastoma

Zebrafish may help researchers to use blood stem cells instead of bone marrow transplants

Honey from strawberry trees stops cell proliferation in colon cancer lines

PDIA1 enzyme levels could help diagnose individuals’ predisposition to cardiovascular disease

Sophisticated molecular machinery is used by dangerous pathogens to infect hosts

First Footage of T-Cells Training To Fight Pathogens Revealed

Circadian rhythm influences immune responses across a range of diseases

Gene linked to rare progressive brain disease causes new kind of congenital disorder

Ultra-Processed foods delay satiety, increase food intake and weight gain

Researchers map molecular structure and dynamics of one of Alzheimer's stickier culprits

New tool provides standards for describing characteristics and use of cell therapies

Mining 25 years of data reveals new insights into predicting the age of onset for Huntington disease

Researchers unravel mechanistic origin of cell-size control

Insulin-producing beta cells can change their function in diabetes, reveals study

New model captures flexibility of working memory

New type of insulin could prevent hypoglycemia in diabetics

Long-term antibiotic treatment slows growth of amyloid plaques in male mice but not in females

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