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First Edition: February 27, 2014

Today's headlines include a number of stories about Obama past and present administration officials -- notably, former Secretary of State Hillary Clinton and Vice President Joe Biden -- who are stepping up to "sell" people on enrolling in new health law insurance coverage.

27 Feb 2014

Pacira Pharmaceuticals initiates Phase 3 clinical trial of EXPAREL in femoral nerve block

Pacira Pharmaceuticals, Inc. (NASDAQ:PCRX) today announced that the Phase 3 clinical trial assessing the safety and efficacy of EXPAREL® (bupivacaine liposome injectable suspension) in femoral nerve block for total knee arthroplasty met its primary efficacy endpoint.

27 Feb 2014

Report: Spending on health care for children increased between 2009 and 2012

Spending on health care for children covered by employer-sponsored insurance (ESI) increased between 2009 and 2012, rising an average 5.5 percent a year, with more dollars spent on boys than girls, and higher spending on infants and toddlers (ages 0-3) than any other children's age group, finds a new report released today by the Health Care Cost Institute. Per capita spending on children reached $2,437 in 2012, a $363 increase from 2009. The study shows a growth in prescription use by children through age 18, as well as a rise in the number of teens being admitted for mental health and substance use (MHSU) treatment.

27 Feb 2014

LA BioMed researchers awarded NIH grant to pursue new approaches for treating MRSA

With antibiotic resistant infections on the rise and a scarce pipeline of novel drugs to combat them, researchers at the Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center are pursuing entirely new approaches to meet the challenge of drug-resistant infections by taming microbes rather than killing them.

27 Feb 2014

Dampening immune response may encourage lung transplant rejection

Organ transplant patients routinely receive drugs that stop their immune systems from attacking newly implanted hearts, livers, kidneys or lungs, which the body sees as foreign.

27 Feb 2014

Medicare official defends proposed changes to prescription drug program

In written testimony, Jonathan Blum, deputy administrator of the Centers For Medicare & Medicaid Services, says the changes are needed to head off cost increases, but an industry-sponsored study argues some of the changes could cost taxpayers more.

27 Feb 2014

Altheus Therapeutics completes dosing of ZA201 in Phase 2 trial of Zoenasa for ulcerative colitis

Altheus Therapeutics, Inc., announced completion of dosing in ZA201, a double-blind, active-controlled Phase 2 trial evaluating the efficacy and safety of Zoenasa® Rectal Gel versus mesalamine enema in 120 patients with left-sided ulcerative colitis.

27 Feb 2014

ViroXis signs agreement with global pharmaceutical for marketing of OTC sandalwood oil-containing product

ViroXis Corporation is pleased to report the execution of an exclusive license agreement with a global pharmaceutical company for the marketing of an over-the-counter (OTC) sandalwood oil-containing product.

26 Feb 2014

Nurses in emergency care must be trained to recognise symptoms of meningococcal septicaemia

Nurses working in emergency care environments must be trained to recognise the atypical signs and symptoms of meningococcal septicaemia.

26 Feb 2014

Regeneron receives FDA acceptance for EYLEA injection for treatment of macular edema

Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) today announced that the U.S. Food and Drug Administration (FDA) has accepted for standard review the Company's supplemental Biologics License Application (sBLA) for EYLEA® (aflibercept) Injection for the treatment of Macular Edema following Branch Retinal Vein Occlusion (BRVO).

26 Feb 2014

New way to potentially block chronic pain affecting osteoarthritis sufferers

Researchers from the Arthritis Research UK Pain Centre at The University of Nottingham have discovered a new way to potentially block the chronic and often debilitating pain affecting osteoarthritis sufferers.

26 Feb 2014

Study: Rate of mother to child HIV transmission is at an all-time low in the UK

The rate of mother to child HIV transmission is at an all-time low in the UK, according to a paper published today in the journal AIDS.

26 Feb 2014

Scales of zebrafish suitable for identifying new drugs for treating bone diseases

The scales of the zebrafish are very suitable for identifying potential new drugs for treating bone diseases. This is good news because it means fewer mice and rats will be needed for that work.

26 Feb 2014

Researchers develop new compound that slows down progression of Huntington's Disease

Juliet Ross is suffering from Huntington's Disease, a rare neurological disorder that affects one in 10.000 people. Due to a genetic defect, her body produces a toxic protein that damages neurons in her brain.

26 Feb 2014

Biothera’s Phase 2b clinical trial in NSCLC presented at International Association for the Study of Lung Cancer

Biothera presented results of its Phase 2b clinical trial in non-small cell lung cancer (NSCLC) this past weekend to top clinicians and scientists at the invitation-only International Association for the Study of Lung Cancer meeting on targeted therapies in Santa Monica, CA.

26 Feb 2014

New optical device may help docs to diagnose blood coagulation status in near real time

Defective blood coagulation is one of the leading causes of preventable death in patients who have suffered trauma or undergone surgery. The body's natural defense against severe blood loss is the clotting process, in which platelets, plasma proteins, and other blood components interact to form a sticky, mesh-like structure.

26 Feb 2014

Study shows psychological, interpersonal effects of antidepressants have reached bizarre levels

A University of Liverpool researcher has shown that thoughts of suicide, sexual difficulties and emotional numbness as a result of anti-depressants may be more widespread than previously thought.

26 Feb 2014

Substance abuse worsens course of first-episode psychosis

Patients with first-episode psychosis who also present with substance abuse have a higher rate of hospitalisation after 12 months than their peers who do not, an Italian study reports.

25 Feb 2014

S. pneumoniae highly prevalent in urban Indonesians, especially children

Streptococcus pneumoniae is present in the nasopharyngeal mucosa in nearly half of children under the age of 5 years and one in 10 adults living in Java Island, Indonesia, a survey has found.

25 Feb 2014

Researchers produce extremely accurate and detailed images of "toxic injections"

Bacteria have developed many different ways of smuggling their toxic cargo into cells. Tripartite Tc toxin complexes, which are used by bacteria like the plague pathogen Yersinia pestis and the insect pathogen Photorhabdus luminescens, are particularly unusual.

25 Feb 2014

Drugs News and Research

First Edition: February 27, 2014

Pacira Pharmaceuticals initiates Phase 3 clinical trial of EXPAREL in femoral nerve block

Report: Spending on health care for children increased between 2009 and 2012

LA BioMed researchers awarded NIH grant to pursue new approaches for treating MRSA

Dampening immune response may encourage lung transplant rejection

Medicare official defends proposed changes to prescription drug program

Altheus Therapeutics completes dosing of ZA201 in Phase 2 trial of Zoenasa for ulcerative colitis

ViroXis signs agreement with global pharmaceutical for marketing of OTC sandalwood oil-containing product

Nurses in emergency care must be trained to recognise symptoms of meningococcal septicaemia

Regeneron receives FDA acceptance for EYLEA injection for treatment of macular edema

New way to potentially block chronic pain affecting osteoarthritis sufferers

Study: Rate of mother to child HIV transmission is at an all-time low in the UK

Scales of zebrafish suitable for identifying new drugs for treating bone diseases

Researchers develop new compound that slows down progression of Huntington's Disease

Biothera’s Phase 2b clinical trial in NSCLC presented at International Association for the Study of Lung Cancer

New optical device may help docs to diagnose blood coagulation status in near real time

Study shows psychological, interpersonal effects of antidepressants have reached bizarre levels

Substance abuse worsens course of first-episode psychosis

S. pneumoniae highly prevalent in urban Indonesians, especially children

Researchers produce extremely accurate and detailed images of "toxic injections"

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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