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New findings yield insights into factors that contribute to aggressive endometrial tumors

New research from Huntsman Cancer Institute at the University of Utah indicates steroid and hormone receptors are simultaneously active in many endometrial cancer tissues.

13 Mar 2018

Researchers identify B immune cells that promote axon myelination in developing neurons

Neurons are specialized cells of the nervous system that communicate using electrical signals, which propagate down long, wire-like projections called axons. The conduction of these signals requires myelin, a fatty substance that surrounds axons in much the same way that plastic coating surrounds an electrical wire.

13 Mar 2018

Researchers create cardiomyocyte molds to mend broken hearts

2.5 billion. That's approximately the number of times the human heart beats in 70 years. And sometimes during the course of its unrelenting contractions and relaxations, the heart muscle can no longer bear the strain.

13 Mar 2018

Study: Soy-fed infants have differences in reproductive system tissues

Infants who consumed soy-based formula as newborns had differences in some reproductive-system cells and tissues, compared to those who used cow-milk formula or were breastfed, according to a new study.

13 Mar 2018

Extracellular vesicles may serve as drug delivery vehicles for cancer treatment

Creating enough nanovesicles to inexpensively serve as a drug delivery system may be as simple as putting the cells through a sieve, according to an international team of researchers who used mouse autologous -- their own -- immune cells to create large amounts of fillable nanovesicles to deliver drugs to tumors in mice.

13 Mar 2018

NIH-funded researchers use CRISPR to rapidly find new genetic suspects behind ALS, FTD

NIH-funded researchers at Stanford University used the gene editing tool CRISPR-Cas9 to rapidly identify genes in the human genome that might modify the severity of amyotrophic lateral sclerosis and frontotemporal dementia caused by mutations in a gene called C9orf72.

13 Mar 2018

Study uses ACEA Biosciences’ xCELLigence assay to monitor disruption of S. aureus biofilms

Biofilms are surface-attached communities of bacterial or fungal cells that are enmeshed in an extensive extracellular matrix which makes them more resistant to both antibiotics and the immune system.

13 Mar 2018

ACEA goes live with exhaustive, searchable library of NovoCyte publications

With the 2014 release of its NovoCyte flow cytometer ACEA Biosciences delivered a highly innovative instrument at an extremely competitive price point. In the ensuing three years features such as automated fluidics protocols, a highly flexible and upgradable optical platform, autosampling, direct volumetric cell counting, and the industry leading NovoExpress software have enabled the NovoCyte to quickly gain broad market penetrance.

13 Mar 2018

ACEA launches comprehensive and searchable online library of xCELLigence papers

In 2002 ACEA Biosciences pioneered real-time cellular impedance as a tool for dynamically tracking cell number, cell size, cell-substrate attachment strength, and cell invasion/migration.

13 Mar 2018

Korean scientists track growth, migration of cells under hypoxic conditions using xCELLigence RTCA

Tracking the growth and migration of cells under hypoxic conditions in vitro can be challenging because measurements must be made in a manner that does not perturb the atmospheric composition of the closed system.

13 Mar 2018

Continuous tracking of melanoma cell invasion helps scientists explain key regulators of metastasis

A team of Italian scientists reported this week that blocking the interaction between urokinase receptor (uPAR) and formyl peptide receptor type 1 (FPR1) suppresses the ability of melanoma cells to migrate, invade through an extracellular matrix, and to burrow through a layer of endothelial cells.

13 Mar 2018

Transformative new approach for viral titer determination using xCELLigence RTCA

Accurate determination of viral titers is critical to vaccine development. Historically, titers have been determined using endpoint assays which are labor-intensive, expensive, and time-consuming. This is increasingly problematic in modern production facilities where bioprocess optimization is performed using high-throughput cell culture reactors that can produce batches of virus faster than they can be analyzed.

13 Mar 2018

Scientists develop novel assay for studying molecular determinants of bronchoconstriction/dilation

Contraction and relaxation of smooth muscle cells and fibroblasts within the bronchial airways dramatically affects airflow, and being able to modulate these processes is critical for treating asthma and allergic responses.

13 Mar 2018

Novel oncolytic virus expressing BiTE molecule elicits T cell-mediated killing of tumor cells

In a research article published in EMBO Molecular Medicine, a group of scientists at the University of Oxford have described a new twist on cancer immunotherapy, combining two independent cell killing approaches in a single therapeutic with high potency and broad applicability.

13 Mar 2018

ACEA Biosciences develops novel assay for rapid identification of endocrine-disrupting chemicals

Endocrine-disrupting chemicals are substances that interfere with the ability of endogenous hormones to regulate homeostasis via their cognate nuclear receptors.

13 Mar 2018

New imaging technology could significantly improve the accuracy of cancer diagnosis

A new cutting-edge imaging technology can grade cancer tumors, thereby eliminating human subjectivity and variability in the grading of cancer severity.

13 Mar 2018

Study sheds new light on viral replication

Viruses are intracellular parasites that cause disease by infecting the cells in the body and, in a study published today in Nature Microbiology, researchers at Children's Hospital of Pittsburgh of UPMC and the University of Pittsburgh School of Medicine showed how a common virus hijacks a host cell's protein to help assemble new viruses before they are released.

13 Mar 2018

Study identifies two new biomarkers for common form of childhood cancer

Two new biomarkers for a type of cancer in children called neuroblastoma have been identified in a study published in the journal Cancer Cell. The findings are expected to have immediate significance for disease prognosis, and eventually also for treatment.

13 Mar 2018

International research consortium identifies 22 new genetic risk factors for stroke

An international research consortium studying 520,000 individuals from around the world has identified 22 new genetic risk factors for stroke, thus tripling the number of gene regions known to affect stroke risk.

13 Mar 2018

Socioeconomic inequalities may affect outcomes for patients with anal cancer

In a study of patients with anal cancer, living in low median household income areas was linked with an increased risk of early death. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings suggest that socioeconomic inequalities may affect cancer outcomes, especially for highly treatable and curable tumors such as anal cancer.

12 Mar 2018

B Cell News and Research

New findings yield insights into factors that contribute to aggressive endometrial tumors

Researchers identify B immune cells that promote axon myelination in developing neurons

Researchers create cardiomyocyte molds to mend broken hearts

Study: Soy-fed infants have differences in reproductive system tissues

Extracellular vesicles may serve as drug delivery vehicles for cancer treatment

NIH-funded researchers use CRISPR to rapidly find new genetic suspects behind ALS, FTD

Study uses ACEA Biosciences’ xCELLigence assay to monitor disruption of S. aureus biofilms

ACEA goes live with exhaustive, searchable library of NovoCyte publications

ACEA launches comprehensive and searchable online library of xCELLigence papers

Korean scientists track growth, migration of cells under hypoxic conditions using xCELLigence RTCA

Continuous tracking of melanoma cell invasion helps scientists explain key regulators of metastasis

Transformative new approach for viral titer determination using xCELLigence RTCA

Scientists develop novel assay for studying molecular determinants of bronchoconstriction/dilation

Novel oncolytic virus expressing BiTE molecule elicits T cell-mediated killing of tumor cells

ACEA Biosciences develops novel assay for rapid identification of endocrine-disrupting chemicals

New imaging technology could significantly improve the accuracy of cancer diagnosis

Study sheds new light on viral replication

Study identifies two new biomarkers for common form of childhood cancer

International research consortium identifies 22 new genetic risk factors for stroke

Socioeconomic inequalities may affect outcomes for patients with anal cancer

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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