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Positive efficacy data from Phase 2 study of AEZS-108 announced

AEterna Zentaris Inc. (the "Company"), a global biopharmaceutical company focused on endocrine therapy and oncology, today announced positive efficacy data from a Phase 2 study with its targeted cytotoxic peptide conjugate, AEZS-108 (formerly AN-152), in patients with advanced or recurrent endometrial cancer.

25 Nov 2009

Positive data from Æterna Zentaris' Phase 2 targeted cytotoxic peptide conjugate study

Æterna Zentaris Inc., a global biopharmaceutical company focused on endocrine therapy and oncology, today announced positive efficacy data from a Phase 2 study with its targeted cytotoxic peptide conjugate, AEZS-108 (formerly AN-152), in patients with advanced or recurrent endometrial cancer.

24 Nov 2009

New finding reveals Barrett's esophagus in asymptomatic women undergoing endoscopic screening

In the November issue of GIE: Gastrointestinal Endoscopy, the monthly peer-reviewed scientific journal of the American Society for Gastrointestinal Endoscopy (ASGE), a study out of Stanford University found that Barrett's esophagus was detected in six percent of asymptomatic women undergoing endoscopic screening.

24 Nov 2009

USGS researchers examine PAHs and PCBs sources in urban environment

Toxic dust: Toxins in coal-tar-based sealcoats in parking lots may be the culprit in contaminated house dust, according to a USGS study. PAHs - or polycyclic aromatic hydrocarbons - are large molecules found in oil, coal and tar deposits, and can have toxic effects.

21 Nov 2009

Gene therapy may hold promise for cryptorchid individuals risking infertility

EGR4 is a master gene responsible for fertility in cryptorchidism. Is gene therapy going to replace surgery?

18 Nov 2009

Combination of night work, overtime and shortened sleep can increase risk of stroke and heart disease

A new study published in the current issue of Archives of Environmental & Occupational Health (vol. 64, No. 3) shows that this combination of night work, overtime and shortened sleep can contribute to the development among police officers of the metabolic syndrome, a combination of unhealthful factors that increase the risk of cardiovascular disease (CVD), primarily heart disease and stroke.

18 Nov 2009

New rapid screening methods for BPA using Waters ACQUITY UPLC published in ASTM International

Waters Corporation (NYSE: WAT) today hosted Dr. Lawrence Zintek, National Organic Methods Development Expert, United States Environmental Protection Agency Region 5 Central Regional Laboratory in Chicago, and author of two new rapid screening methods for Alkylphenols and Bisphenol A (BPA) using Waters® ACQUITY UPLC®/Quattro Premier(TM) XE (UPLC/MS/MS) recently published in American Society for Testing and Materials (ASTM) International. Dr. Zintek was the keynote speaker at a Waters' breakfast seminar held in conjunction with the Water Quality Technology Conference sponsored by the American Water Works Association in Seattle.

17 Nov 2009

Fetal exposure to phthalates has the potential to alter masculine brain development: Study

A study of 145 preschool children reports, for the first time, that when the concentrations of two common phthalates in mothers' prenatal urine are elevated their sons are less likely to play with male-typical toys and games, such as trucks and play fighting.

16 Nov 2009

PKCI/HINT1 gene associated with mood regulation

Removing the PKCI/HINT1 gene from mice has an anti-depressant-like and anxiolytic-like effect. Researchers writing in the open access journal BMC Neuroscience applied a battery of behavioral tests to the PKCI/HINT1 knockout animals, concluding that the deleted gene may have an important role in mood regulation.

13 Nov 2009

New policies to decrease the public's exposure to EDCs; AMA to work with federal government

The American Medical Association's (AMA) House of Delegates adopted a resolution calling on the AMA to work with the federal government to enact new federal policies to decrease the public's exposure to endocrine-disrupting chemicals (EDCs).

11 Nov 2009

First human study to measure effects of BPA on male reproductive system

High levels of workplace exposure to Bisphenol-A may increase the risk of reduced sexual function in men, according to a Kaiser Permanente study appearing in the journal Human Reproduction, published by Oxford Journals.

11 Nov 2009

Scientific article supports AEterna Zentaris' development of perifosine inhibitor

AEterna Zentaris Inc., a global biopharmaceutical company focused on endocrine therapy and oncology, today announced publication of a scientific article in the renowned Journal of Urology, supporting the development of the Company's PI3K/Akt pathway inhibitor oral compound, perifosine, for the treatment of cancer.

9 Nov 2009

CRINONE vaginal progesterone gel as effective as IM progesterone for luteal phase support in IVF-ET

In their American Society of Reproductive Medicine (ASRM) conference wrap-up, Medscape highlighted the article published by them on October 27, 2009, which summarized the results from the largest prospective, randomized clinical study to compare vaginal progesterone to intramuscular progesterone injections (IM progesterone) for luteal support in infertility treatment.

9 Nov 2009

Scientific and medical community mourns the loss of Emeritus Professor James Boyer Brown

The scientific and medical community mourns the loss of our esteemed colleague and good friend Emeritus Professor James Boyer Brown AM, MSc (NZ), PhD (Edin), MSc (Melb), DSc (Edin), FRANZCOG (Ad Eundem), Life Member Fertility Society of Australia, Life Member Endocrine Society of Australia, who passed away on Saturday 31st October 2009, aged 90.

4 Nov 2009

Higher testosterone levels in older women are associated with increased health risks

Postmenopausal women who have higher testosterone levels may be at greater risk of heart disease, insulin resistance and the metabolic syndrome compared to women with lower testosterone levels, according to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

4 Nov 2009

Eating a meal quickly curtails the release of hormones in the gut and can lead to overeating

According to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM), eating a meal quickly, as compared to slowly, curtails the release of hormones in the gut that induce feelings of being full. The decreased release of these hormones, can often lead to overeating.

4 Nov 2009

Eat slowly to avoid overeating

4 Nov 2009

Positive results from Aeterna Zentaris' AEZS-108 Phase 2 study in ovarian cancer patients

AEterna Zentaris Inc., a global biopharmaceutical company focused on endocrine therapy and oncology, today announced positive efficacy data from a Phase 2 study with its targeted cytotoxic peptide conjugate, AEZS-108 (formerly AN-152), in patients with platinum-resistant and taxane-pretreated ovarian cancer.

2 Nov 2009

Dr. Chao Herbal Drink Line releases two all-natural, vegan beverages

The Dr. Chao Herbal Drink Line released two all-natural, vegan beverages to enhance sexual health and combat premenstrual symptoms. The new Adult and Lady drinks have no sugar, artificial sweeteners or preservatives, glutens, and caffeine, do not require costly prescriptions and have health benefits derived from the recipes of a 19th-century Chinese herbalist.

30 Oct 2009

The Endocrine Society urges NIH to increase funding for stem cell research

Stem cell research holds great promise for the treatment of millions of Americans with debilitating and possibly fatal diseases. Current legislation and guidelines, however, continue to limit researchers' endeavors in unlocking the potential breakthroughs that stem cell research can provide. To address this concern, today The Endocrine Society issued a Position Statement (http://www.endo-society.org/advocacy/policy) calling for an increase in NIH funding for stem cell research as well as expanding the scope of funding to include promising yet neglected areas of stem cell research.

28 Oct 2009

Endocrine News and Research

Positive efficacy data from Phase 2 study of AEZS-108 announced

Positive data from Æterna Zentaris' Phase 2 targeted cytotoxic peptide conjugate study

New finding reveals Barrett's esophagus in asymptomatic women undergoing endoscopic screening

USGS researchers examine PAHs and PCBs sources in urban environment

Gene therapy may hold promise for cryptorchid individuals risking infertility

Combination of night work, overtime and shortened sleep can increase risk of stroke and heart disease

New rapid screening methods for BPA using Waters ACQUITY UPLC published in ASTM International

Fetal exposure to phthalates has the potential to alter masculine brain development: Study

PKCI/HINT1 gene associated with mood regulation

New policies to decrease the public's exposure to EDCs; AMA to work with federal government

First human study to measure effects of BPA on male reproductive system

Scientific article supports AEterna Zentaris' development of perifosine inhibitor

CRINONE vaginal progesterone gel as effective as IM progesterone for luteal phase support in IVF-ET

Scientific and medical community mourns the loss of Emeritus Professor James Boyer Brown

Higher testosterone levels in older women are associated with increased health risks

Eating a meal quickly curtails the release of hormones in the gut and can lead to overeating

Eat slowly to avoid overeating

Positive results from Aeterna Zentaris' AEZS-108 Phase 2 study in ovarian cancer patients

Dr. Chao Herbal Drink Line releases two all-natural, vegan beverages

The Endocrine Society urges NIH to increase funding for stem cell research

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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