Malignant News and Research

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Severity of sleep apnoea can independently predict aggressiveness of skin melanoma

The severity of sleep apnoea can independently predict the aggressiveness of malignant skin melanoma, according to a new study.

10 Sep 2013

Researchers investigate importance of STAT1 phosphorylation in NK cells

Since its discovery in the early 1990s, the protein STAT1 (Signal Transducer and Activator of Transcription 1) has been found to be central in passing signals across immune cells, ensuring that our bodies react quickly and appropriately to threats from viruses or other pathogens.

7 Sep 2013

BMP linked to increased risk of benign tumors, not cancers

Patients undergoing spinal fusion surgery with bone morphogenetic protein (BMP) appear to be at increased risk of benign tumors—but not cancers, reports a study in the September issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

7 Sep 2013

ESMO recognises oncologists with prestigious awards

The European Society for Medical Oncology, the leading pan-European organisation representing medical oncology professionals, announced today the recipients of the annual society's prestigious awards, recognising excellence in oncology.

5 Sep 2013

Ontario researchers develop evidence-based recommendations for lung cancer screening

Lung cancer is the most common cause of cancer death in Ontario. Screening for lung cancer using low-dose computed tomography has been the subject of many research studies since the 1990s. The National Lung Screening Trial compared LDCT with chest radiograph in high-risk populations and found a 20 percent reduction in lung cancer mortality at 6 years with LDCT after an initial scan and two annual rounds of screening.

5 Sep 2013

Researchers discover new way to target senescent cancer cells for destruction

Resting cancer cells can be selectively destroyed by inhibiting their energy metabolism. This is the recent discovery by researchers at Charité Universitätsmedizin Berlin and the Max Delbrück Center for Molecular Medicine (MDC) in Berlin-Buch, together with other cooperation partners from Germany. The findings of their study have been published in the scientific journal Nature.

4 Sep 2013

Blind mole-rats live underground in low-oxygen environments, are long-lived and resistant to cancer

Like naked mole-rats (Heterocephalus gaber), blind mole-rats (of the genus Spalax) live underground in low-oxygen environments, are long-lived and resistant to cancer. A new study demonstrates just how cancer-resistant Spalax are, and suggests that the adaptations that help these rodents survive in low-oxygen environments also play a role in their longevity and cancer resistance.

4 Sep 2013

Researchers create specific tests to detect cancer biomarkers in patients with dermatomyositis

Researchers from major universities in the U.S. have developed specific tests to identify cancer biomarkers in patients with dermatomyositis-a systemic inflammatory disease associated with increased risk of malignancy.

3 Sep 2013

Anti-diabetic drug alogliptin meets primary endpoint in EXAMINE trial

Patients with type 2 diabetes and high cardiovascular risk due to recent acute coronary syndromes had similar rates of cardiovascular events when treated with the anti-diabetic agent alogliptin compared to placebo according to results of the Examination of Cardiovascular Outcomes with Alogliptin versus Standard of Care trial presented at the European Society of Cardiology Congress.

2 Sep 2013

Research findings could lead to new therapeutic approaches for liver cancer

Liver cancer (Hepatocellular Carcinoma, HCC) usually arises as the result of a chronic, inflammatory liver disease. The most common causes here are excessive alcohol consumption as well as a high-fat diet and also chronic infection with the hepatitis viruses B and C. In the course of the inflammatory process, the liver cells (hepatocytes) die more frequently due to programmed cell death.

30 Aug 2013

Researchers receive $3M R01 award to test new approach to treating brain tumors

With a five-year, $3 million R01 award from the National Institutes of Health, through the National Cancer Institute, a team of researchers led by Gregory Fischer, PhD, assistant professor of mechanical engineering and robotics engineering at Worcester Polytechnic Institute and director of WPI's Automation and Interventional Medicine Laboratory, will test a new, minimally invasive approach to treating brain tumors that promises to accurately destroy malignant tissue while leaving surrounding tissue unaffected.

30 Aug 2013

Researchers find new form of imaging technology to diagnose different types of cancer

Researchers from University Hospitals Case Medical Center have published findings that a new form of imaging -- PET/MRI -- is promising for several types of cancer.

30 Aug 2013

Malignant Hyperthermia Scientific Conference to be held at University of Toronto

The 2013 Malignant Hyperthermia (MH) Scientific Conference is being held at the Chestnut Conference Centre, University of Toronto, Canada on November 1st and 2nd, 2013 and is sponsored by Malignant Hyperthermia Association of the United States (MHAUS) in conjunction with The University of Toronto.

29 Aug 2013

FDA approves NDA filing for ibrutinib inhibitor in two B-cell malignancies

Pharmacyclics, Inc. (Nasdaq: PCYC) today announced that the U.S. Food and Drug Administration (FDA) has accepted for filing its New Drug Application (NDA) for the investigational oral Bruton's tyrosine kinase (BTK) inhibitor ibrutinib, for two B-cell malignancy indications: previously treated mantle cell lymphoma (MCL) and previously treated chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL).

29 Aug 2013

Study shows genetic test to classify gastric cancers and match them to therapies offer best outcomes

Stomach cancer, one of the leading causes of cancer death worldwide, actually falls into three broad subtypes that respond differently to currently available therapies, according to researchers at Duke-NUS Graduate Medical School Singapore.

28 Aug 2013

Report shows women affected by DCIS prefer nonsurgical treatments

When ductal carcinoma in situ (DCIS, a preinvasive malignancy of the breast) is described as a high-risk condition rather than cancer, more women report that they would opt for nonsurgical treatments, according to a research letter by Zehra B. Omer, B.A., of Massachusetts General Hospital—Institute for Technology Assessment, Boston, and colleagues.

28 Aug 2013

Virttu Biologics treats first cohort of patients in SEPREHVIR Phase I/IIa study

Virttu Biologics Limited, a UK biotechnology company with expertise in the field of oncolytic viruses, has announced that it has treated the first cohort of patients in its Phase I/IIa clinical study of its oncolytic virus, SEPREHVIR (HSV1716) for the treatment of malignant pleural mesothelioma.

27 Aug 2013

Northwestern surgical oncologists use minimally invasive procedure to remove malignant melanoma

That's when she received the results from her dermatologist, who removed a part of the blister and had it tested. It turns out that little red bump was malignant melanoma, the leading cause of skin cancer death in the United States. It's a cancer that kills one person every hour, which translates to more than 8,700 Americans each year.

27 Aug 2013

Microscopic material in cells offers robust treatment for stroke

In the latest in a series of experiments testing the use of stem cells to treat neurological disease, researchers at Henry Ford Hospital have shown for the first time that microscopic material in the cells offers a "robust" treatment for crippling stroke.

27 Aug 2013

Screening strategy for ovarian cancer appears to be highly specific for detecting disease at early stages

A new screening strategy for ovarian cancer appears to be highly specific for detecting the disease before it becomes lethal. The strategy is described in a study published early online in Cancer, a peer-reviewed journal of the American Cancer Society. If verified in an ongoing clinical trial, it could potentially help save the lives of thousands of women each year in the United States alone.

26 Aug 2013

Malignant News and Research

Severity of sleep apnoea can independently predict aggressiveness of skin melanoma

Researchers investigate importance of STAT1 phosphorylation in NK cells

BMP linked to increased risk of benign tumors, not cancers

ESMO recognises oncologists with prestigious awards

Ontario researchers develop evidence-based recommendations for lung cancer screening

Researchers discover new way to target senescent cancer cells for destruction

Blind mole-rats live underground in low-oxygen environments, are long-lived and resistant to cancer

Researchers create specific tests to detect cancer biomarkers in patients with dermatomyositis

Anti-diabetic drug alogliptin meets primary endpoint in EXAMINE trial

Research findings could lead to new therapeutic approaches for liver cancer

Researchers receive $3M R01 award to test new approach to treating brain tumors

Researchers find new form of imaging technology to diagnose different types of cancer

Malignant Hyperthermia Scientific Conference to be held at University of Toronto

FDA approves NDA filing for ibrutinib inhibitor in two B-cell malignancies

Study shows genetic test to classify gastric cancers and match them to therapies offer best outcomes

Report shows women affected by DCIS prefer nonsurgical treatments

Virttu Biologics treats first cohort of patients in SEPREHVIR Phase I/IIa study

Northwestern surgical oncologists use minimally invasive procedure to remove malignant melanoma

Microscopic material in cells offers robust treatment for stroke

Screening strategy for ovarian cancer appears to be highly specific for detecting disease at early stages

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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