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Cogstate technology to be applied in paediatric clinical trial in the U.S.

Medical technology company Cogstate Limited has today announced its technology will be used in a large paediatric clinical trial in the United States.

12 Feb 2014

Scientists receive €85 million international drive to develop new and effective drugs

An increasing biological resistance to antibiotics treatment is to be countered by Aston University scientists who will lead a €85 million international drive to develop new and effective drugs.

12 Feb 2014

PAREXEL launches marketing initiative to simplify journey from science to new treatments

As the global biopharmaceutical industry increasingly seeks to streamline the complex process of bringing new drugs to market, PAREXEL International Corporation, a leading global biopharmaceutical services provider, today announced the launch of a new marketing initiative that highlights the Company's proven approach to help clients simplify the journey from science to new treatments.

From Parexel 12 Feb 2014

Chronic stress generates long-term changes in brain that lead to mental problems

University of California, Berkeley, researchers have shown that chronic stress generates long-term changes in the brain that may explain why people suffering chronic stress are prone to mental problems such as anxiety and mood disorders later in life.

12 Feb 2014

GAO: Medicine shortages remain stubbornly high

The Food and Drug Administration has made progress in addressing some immediate causes of drug shortages, but the total number of shortages remains high, according to a Government Accountability Office report issued Monday (Ethridge, 2/10).

12 Feb 2014

MIT develops robot that may speed up drug development for stroke patients

The development of drugs to treat acute stroke or aid in stroke recovery is a multibillion-dollar endeavor that only rarely pays off in the form of government-approved pharmaceuticals.

12 Feb 2014

Microbiologists find way to use statins to fight Hantavirus

wo Perelman School of Medicine microbiologists may have found a way to use statins, the well-known blockbuster cholesterol-lowering drugs, to fight the hantavirus, a mysterious and lethal microorganism that appeared suddenly in the US southwest over 20 years ago.

12 Feb 2014

Researchers examine how evolution relates to health

February 12 marks the birth of the 19th century naturalist Charles Darwin, who launched the scientific study of evolution. While Darwin's theory laid the groundwork, ongoing studies have deepened our understanding of evolution, including how it relates to health. Research funded by the National Institutes of Health has helped answer many questions about evolution, health and medicine. Here's a sampling.

12 Feb 2014

Manchester researchers become first in world to assess all genetic links with fungal lung infection CPA

A grandfather-of-three from Tameside is helping University of Manchester researchers become the first in the world to assess all the genetic links with Chronic Pulmonary Aspergillosis (CPA) - a debilitating fungal lung infection that claims the lives of thousands of people in the UK and millions more worldwide.

From The University of Manchester 12 Feb 2014

Avaxia Biologics receives patent for oral anti-TNF antibodies for treatment of IBD

Avaxia Biologics, Inc., a clinical-stage biopharmaceutical company developing gut-targeted therapeutics, announced today that the company was awarded U.S. Patent No. 8,647,626, entitled "Compositions Comprising TNF-specific Antibodies for Oral Delivery."

12 Feb 2014

FDA approves two drugs for long-term weight loss

Options are limited in America's battle of the bulge. While diet and exercise can help in the short term, they are frustratingly ineffective in the long run.

12 Feb 2014

Protein plays previously unknown role in acute myeloid leukemia development

There are potentially effective treatments for acute myeloid leukemia (AML), but they only work in 20 to 40 percent of cases. In a paper published today in Leukemia, a Nature journal, a UT Health Science Center researcher has pinpointed a protein that could play a key, previously unknown role in the development of pediatric AML - promising new information in the quest to treat and cure childhood leukemias.

12 Feb 2014

Researchers discover that bladder cancer shares genetic similarities with two forms of breast cancer

Researchers at the UNC School of Medicine conducted a comprehensive genetic analysis of invasive bladder cancer tumors to discover that the disease shares genetic similarities with two forms of breast cancer.

12 Feb 2014

Researchers demonstrate new approach to treating muscular dystrophy

Researchers at Washington University School of Medicine in St. Louis have demonstrated a new approach to treating muscular dystrophy. Mice with a form of this muscle-weakening disease showed improved strength and heart function when treated with nanoparticles loaded with rapamycin, an immunosuppressive drug recently found to improve recycling of cellular waste.

12 Feb 2014

EMT program in human cells may provide an effective approach for treating triple-negative breast cancer

A new study led by University of Kentucky Markey Cancer Center researcher Peter Zhou shows that targeting Twist, a nuclear protein that is an accelerant of the epithelial-mesenchymal transition (EMT) program in human cells, may provide an effective approach for treating triple-negative breast cancer.

12 Feb 2014

IMF announces approval of POMALYST medication in Canada for patients with myeloma

The International Myeloma Foundation - improving the quality of life of myeloma patients while working toward prevention and a cure - said POMALYST (pomalidomide) approval by Health Canada provides patients the most up-to-date oral therapy available for patients who have exhausted all other treatments.

11 Feb 2014

Jazz Pharmaceuticals' Versacloz now commercially available in the U.S. for schizophrenia

Jazz Pharmaceuticals plc today announced U.S. commercial availability of Versacloz (clozapine, USP) oral suspension, the first and only oral suspension clozapine for severely ill treatment-resistant schizophrenia patients or those at risk of recurrent suicidal behavior with schizophrenia or schizoaffective disorder.

11 Feb 2014

New approach for reducing levels of toxic protein fragments associated with Huntington's disease

An innovative therapeutic strategy for reducing the levels of toxic protein fragments associated with Huntington's disease uses a new approach called exon skipping to remove the disease-causing component of the essential protein, huntingtin.

11 Feb 2014

Ario Pharma begins XEN-0501 Phase IIa study for treatment persistent cough in COPD patients

Ario Pharma Ltd, the Cambridge biopharmaceutical company developing innovative new approaches to treat respiratory disease, announced today that it has commenced a Phase IIa study of its TRPV1 antagonist, XEN-0501, for the treatment and prevention of cough in patients with chronic obstructive pulmonary disease (COPD). Persistent cough in COPD and other respiratory conditions present as a huge unmet medical need, with novel therapies urgently needed to improve the quality of life of patients.

11 Feb 2014

Tamoxifen drug appears to kill fungus associated with deadly brain infection

The drug tamoxifen appears to kill a fungus associated with a deadly brain infection that afflicts HIV/AIDS patients, according to a University of Rochester study published online today by mBio, the journal of the American Society for Microbiology.

11 Feb 2014

Drugs News and Research

Cogstate technology to be applied in paediatric clinical trial in the U.S.

Scientists receive €85 million international drive to develop new and effective drugs

PAREXEL launches marketing initiative to simplify journey from science to new treatments

Chronic stress generates long-term changes in brain that lead to mental problems

GAO: Medicine shortages remain stubbornly high

MIT develops robot that may speed up drug development for stroke patients

Microbiologists find way to use statins to fight Hantavirus

Researchers examine how evolution relates to health

Manchester researchers become first in world to assess all genetic links with fungal lung infection CPA

Avaxia Biologics receives patent for oral anti-TNF antibodies for treatment of IBD

FDA approves two drugs for long-term weight loss

Protein plays previously unknown role in acute myeloid leukemia development

Researchers discover that bladder cancer shares genetic similarities with two forms of breast cancer

Researchers demonstrate new approach to treating muscular dystrophy

EMT program in human cells may provide an effective approach for treating triple-negative breast cancer

IMF announces approval of POMALYST medication in Canada for patients with myeloma

Jazz Pharmaceuticals' Versacloz now commercially available in the U.S. for schizophrenia

New approach for reducing levels of toxic protein fragments associated with Huntington's disease

Ario Pharma begins XEN-0501 Phase IIa study for treatment persistent cough in COPD patients

Tamoxifen drug appears to kill fungus associated with deadly brain infection

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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