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UC Riverside researchers discover way to halt cancer metastasis

A research team at the University of California, Riverside has discovered a way for chemotherapy drug paclitaxel to target migrating, or circulating, cancer cells, which are responsible for the development of tumor metastases.

23 Feb 2018

Stiffness of cancer cell plasma membrane affects uptake of nanomedicines

Nanomedicines need to get taken up by diseased cells in order to release their cargo. Cancer cells have altered membrane properties, which hamper their ability to take up nanomedicines.

23 Feb 2018

Rare immune cell may prove to be potent weapon in fighting against cancer

One of the rarest of immune cells, unknown to scientists a decade ago, might prove to be a potent weapon in stopping cancer from spreading in the body, according to new research from the University of British Columbia.

23 Feb 2018

Researchers explore how evolutionary processes guide pathways of cells

Evolution describes how all living forms cope with challenges in their environment, as they struggle to persevere against formidable odds. Mutation and selective pressure--cornerstones of Darwin's theory--are the means by which organisms gain an advantageous foothold or pass into oblivion.

23 Feb 2018

Cell therapy for heart disease caused by muscular dystrophy also improves limb strength, study shows

Injections of cardiac progenitor cells help reverse the fatal heart disease caused by Duchenne muscular dystrophy and also lead to improved limb strength and movement ability, a new study shows.

23 Feb 2018

Sartorius’ second Research Xchange Forum spotlights regenerative medicine and cell therapy

Promoting interdisciplinary exchange between science and industry on the topics of regenerative medicine and cell therapy: this is the objective Sartorius will be pursuing by hosting its second Research Xchange Forum on March 20 and 21, 2018, at Sartorius College in Goettingen.

From Sartorius 23 Feb 2018

New discovery could accelerate clinical translation of stem cell-based therapies

A team of scientists from the University of Colorado School of Medicine and the Charles C. Gates Center for Regenerative Medicine at CU Anschutz has reported a more efficient approach to reprogramming a patient's diseased skin cells into stem cells, raising hopes for future clinical trials and potential cures for critical illnesses.

23 Feb 2018

Researchers describe important step toward gene therapy for patients with Sandhoff disease

Babies with the rare, deadly genetic disorder Sandhoff disease begin to miss developmental milestones just months after birth. Lacking muscle tone, they never learn to sit up, develop heads too large to lift and eventually suffer uncontrollable seizures. There is no cure.

22 Feb 2018

Schizophrenia may be related to neurodevelopment changes, study says

Schizophrenia may be related to neurodevelopment changes, including brain's inability to create the appropriate vascular system, according to new study resulted from a partnership between the D'Or Institute for Research and Education, the University of Chile and the Federal University of Rio de Janeiro.

22 Feb 2018

UT Dallas researchers use new technique to isolate cancer stem cells

Researchers at The University of Texas at Dallas have devised a new technique to isolate aggressive cells thought to form the root of many hard-to-treat metastasized cancers -- a significant step toward developing new drugs that might target these cells.

22 Feb 2018

Calorie restriction improves intestinal-tissue regeneration after injury

Dramatic calorie restriction, diets reduced by 40 percent of a normal calorie total, have long been known to extend health span, the duration of disease-free aging, in animal studies, and even to extend life span in most animal species examined.

22 Feb 2018

UCLA researchers use fluorescent colored proteins to trace origin of heart cells

UCLA researchers used fluorescent colored proteins to trace how cardiomyocytes -- cells in heart muscle that enable it to pump blood -- are produced in mouse embryos. The findings could eventually lead to methods for regenerating heart tissue in human adults.

22 Feb 2018

Research consortium develops first 3D computer model of metabolic processes

An international research consortium developed, with significant involvement of Luxembourg Centre for Systems Biomedicine scientists, the first computer model to include 3D in the representation of human metabolic processes.

22 Feb 2018

Scientists decode molecular structure of healthy huntingtin protein

Mutations on a single gene, the huntingtin gene, are the cause of Huntington's disease. They lead to an incorrect form of the correspondent protein.

22 Feb 2018

Epigenetic changes due to normal aging process linked to cancer risk

Some scientists have hypothesized that tumor-promoting changes in cells during cancer development--particularly an epigenetic change involving DNA methylation--arise from rogue cells escaping a natural cell deterioration process called senescence.

22 Feb 2018

Researchers discover new regulator of the immune system

Academy Professor Riitta Lahesmaa's research group from Turku Centre for Biotechnology of the University of Turku and Åbo Akademi University, Finland, has discovered a new regulator of the immune system, a key factor that controls development of regulatory T cells.

22 Feb 2018

Carbon monoxide enhances efficacy of antibiotic against stomach infection

Carbon monoxide can improve the effectiveness of antibiotics, making bacteria more sensitive to antibiotic medication, according to a study led by Georgia State University.

22 Feb 2018

Scientists discover new treatment approach to curb severe myocarditis

The outcome of viral myocarditis is closely associated with the immune response of the affected individual. An inhibitor of the immunoproteasome, a protein degradation complex in immunocompetent cells, reduces the extent of the inflammation and thus also the damage to the heart during myocarditis.

22 Feb 2018

Researchers discover new interaction mechanism of unstructured proteins

Proteins are among the most important biomolecules and are the key mediators of molecular communication between and within cells. For two proteins to be able to bind, specific regions of their three-dimensional structure have to exactly match one another - like a key that fits into a lock.

22 Feb 2018

Aggressive cancer stem cells can now be isolated successfully in a scientific breakthrough

University of Texas at Dallas researchers have managed to formulate a new technique by which they can isolate aggressive cells which can be the main cause behind metastasized cancers or cancers that have spread to other major organs from their primary site of occurrence.

22 Feb 2018