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Researchers discover that activation of specific enzyme may help suppress tumor metastasis

To stop the spread of cancer, cancer cells must die. Unfortunately, many types of cancer cells seem to use innate mechanisms that block cancer cell death, therefore allowing the cancer to metastasize.

19 Feb 2018

Scientists uncover how newly discovered gene helps grow blood vessels

A new study published today found that a newly discovered gene helps grow blood vessels when it senses inadequate blood flow to tissues.

19 Feb 2018

Scientists identify four viruses that can produce insulin-like hormones

Every cell in your body responds to the hormone insulin, and if that process starts to fail, you get diabetes. In an unexpected finding, scientists at Joslin Diabetes Center have identified four viruses that can produce insulin-like hormones that are active on human cells.

19 Feb 2018

Clinical trial studying type 1 diabetes reaches full enrollment

A clinical trial studying type 1 diabetes has reached full enrollment. The Sanford Project: T-Rex Study, a Phase 2 clinical trial conducted collaboratively by Sanford Health and Caladrius Biosciences, Inc., has completed enrollment of 110 children with type 1 diabetes. The study started with two sites at Sanford Health in Sioux Falls, South Dakota, and Fargo, North Dakota, and expanded to 13 additional sites across the United States.

19 Feb 2018

Study reveals functional dynamics of ion channels

Most ion channels are very selective about the ions, which may or may not pass through them. They may be conductive for potassium ions and non-conductive for sodium ions or vice versa.

19 Feb 2018

Key protein involved in epigenetic regulation of gene expression guides skin cell renewal

Approximately once a month, our skin completely renews itself. If this highly coordinated process goes awry, it can lead to a variety of skin diseases, ranging from skin cancer to psoriasis.

19 Feb 2018

'Click chemistry' approach may improve disease-fighting properties of drugs

Researchers at The Scripps Research Institute have developed a quick and easy way to simultaneously modify dozens of drugs or molecules to improve their disease-fighting properties.

19 Feb 2018

Researchers develop sensing method for early detection of cancer and diabetes

The use of terahertz waves for biosensing is currently receiving considerable attention. THz waves are able to detect molecular vibrations and rotations, without using labels that can affect the properties of the substances of interest.

19 Feb 2018

Scientists develop water-soluble warped nanographene for bioimaging

An international team of scientists has developed a water-soluble "warped nanographene", a flexible molecule that is biocompatible and shows promise for fluorescent cell imaging.

19 Feb 2018

Lab-grown cerebellar cells may help explain how ASD develops at molecular level

Increasing evidence has linked autism spectrum disorder with dysfunction of the brain's cerebellum, but the details have been unclear. In a new study, researchers at Boston Children's Hospital used stem cell technology to create cerebellar cells known as Purkinje cells from patients with tuberous sclerosis complex, a genetic syndrome that often includes ASD-like features.

19 Feb 2018

Liquid biopsies could be used as new predictive marker for metastatic TNBC

A clinically relevant "liquid biopsy" test can be used to profile cancer genomes from blood and predict survival outcomes for patients with metastatic triple negative breast cancer, according to new research published by a multi-institutional team of researchers with The Ohio State University Comprehensive Cancer Center -- Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, the Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard.

19 Feb 2018

Researchers reveal potential biological roots behind individuality

Scientists have studied the system that controls age-appropriate behavior and discovered a certain element of variation that may contribute to a species’ survival from an evolutionary point of view.

19 Feb 2018

Researchers uncover how excess calcium may influence development of Parkinson’s disease

Researchers have found that excess levels of calcium in brain cells may lead to the formation of toxic clusters that are the hallmark of Parkinson's disease.

19 Feb 2018

Early childhood immune signature predicts risk of developing asthma later on

Asthma is a chronic inflammatory disease driven by the interplay of genetics, environmental factors and a diverse cast of immune cells.

19 Feb 2018

Research finds rising trend in incidence of merkel cell carcinoma

Merkel cell carcinoma is a rare type of skin cancer, affecting only a few thousand people each year, compared to tens of thousands with melanoma. But while it may not be as common as other skin cancers, MCC is highly aggressive and often deadly - and it's also becoming more common, according to new research published in the Journal of the American Academy of Dermatology and presented at the American Academy of Dermatology 2018 Annual Meeting in San Diego.

19 Feb 2018

Researchers uncover Ras protein's role in uncontrolled cancer growth

Protein systems, such as Ras, make up the complex signaling pathways that control whether a cell divides or, in some cases, becomes cancerous and metastasizes into other regions of the body. For example, 98 percent of pancreatic cancers show Ras protein mutations.

19 Feb 2018

Study sheds light on biology that guides behavior across different stages of life

Put 50 newborn worms in 50 separate containers, and they'll all start looking for food at roughly the same time. Like members of other species, microscopic C. elegans roundworms tend to act like other individuals their own age.

19 Feb 2018

IncuCyte S3 provides real-time around-the-clock live-cell analysis

No matter the time of day or night, see exactly what happened to your cells and when. Biological processes are dynamic, and a single snapshot in time may not capture rare or transient events, causing you to miss a relevant response.

19 Feb 2018

Scientists develop fluorescent probe to identify cancer stem cells

Cells with stem-cell characteristics appear to be especially important in the formation and metastasis of tumors. Scientists have now developed a universal fluorescent probe for these “cancer stem cells”. As reported in the journal Angewandte Chemie, this dye also selectively kills off the cells.

19 Feb 2018

Russian researchers develop new multi-layered biodegradable scaffolds

A team of young researchers at the National University of Science and Technology has recently presented its new development – therapeutic material based on nanofibers of polycaprolactone, modified with plasma-deposited thin layers enriched with antibacterial composition and human blood plasma components.

19 Feb 2018