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Study reports racial, ethnic differences in incidence of soft tissue sarcomas in young adults, adolescents

Mei-Chin Hsieh, MSPH, CTR, of LSU Health Sciences Center New Orleans School of Public Health's Louisiana Tumor Registry, is the lead author of a study that reports racial and ethnic differences in the incidence of soft tissue sarcomas in adolescents and young adults.

26 Aug 2013

Scientists Shed New Light On Malignant Pancreatic Cancer

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23 Aug 2013

Scientists identify molecular mechanism that contributes to pancreatic cancer

New research led by scientists at The University of Texas Health Science Center at Houston (UTHealth) and Baylor College of Medicine could aid efforts to diagnose and treat one of the most lethal and hard-to-treat types of cancer.

23 Aug 2013

People exposed to hot environments may develop Malignant hyperthermia

There is mounting evidence that some people who are susceptible to Malignant hyperthermia (MH) will develop MH when exposed to hot environments or with exercise.

22 Aug 2013

Oncopeptides launches phase II study to determine efficacy of melflufen in treatement of multiple myeloma

Oncopeptides AB, a company working to enhance oncology therapies, today announced that the first patient has been dosed as part of a Phase II study in multiple myeloma patients with its drug candidate melflufen (previously called J1).

21 Aug 2013

Multi-site trial shows BI-RADS 3 breast lesions reduce patient anxiety, unnecessary biopsies

Based on data from a multi-site imaging trial involving more than 2,600 women, researchers say breast lesions categorized as 'probably benign' on supplemental screening ultrasound could be re-evaluated with imaging in 12 months, reducing patient anxiety, follow-up exams and unnecessary biopsies. Results of the study are published online in the journal Radiology.

20 Aug 2013

Researchers identify key transcription factor linked with treatment-resistant prostate cancer

Prostate cancer is one of the most common forms of cancer in men and the leading cause of cancer deaths in white, African-American and Hispanic men, according to the Centers for Disease Control. Current treatment of prostate cancer targets androgens, hormones which promote the growth and spread of cancer cells.

20 Aug 2013

Evidence shows bevacizumab therapy improves survival in patients with glioblastoma

A new population-based study has found that patients with glioblastoma who died in 2010, after the Food and Drug Administration (FDA) approval of bevacizumab, had lived significantly longer than patients who died of the disease in 2008, prior to the conditional approval of the drug for the treatment of the deadly brain cancer. Bevacizumab is used to treat patients with certain cancers whose cancer has spread. The study appears in the journal Cancer.

20 Aug 2013

Report demonstrates clinical use of novel biomarker to assess cancer progression, inflammation

A groundbreaking peer reviewed case report by Dr. Isaac Eliaz, M.D. of Amitabha Medical Clinic, demonstrates for the first time the clinical use of novel biomarker galectin-3 to assess cancer progression and inflammation.

19 Aug 2013

New antibodies estimate risk of polyps developing into bowel cancer

Polyps in the mucosa of the colon are a common finding during screening colonoscopies. Some sub-groups of polyps are classed as precursors of bowel cancer. Until now, it has not been possible to precisely estimate the risk of these polyps developing into bowel cancer.

19 Aug 2013

Researchers discover how common oral bacterium can contribute to colorectal cancer

Researchers from Case Western Reserve University School of Dental Medicine have discovered how a common oral bacterium can contribute to colorectal cancer, a finding that opens promising new research avenues for the development of approaches to prevent and treat the disease.

16 Aug 2013

German researchers discover miRNAs, which determine malignancy of urinary bladder cancers

German researchers have identified four biomarkers that correctly determine malignancy of urinary bladder cancers and contribute to the accurate prediction of patient outcomes. Their results are published in the September issue of The Journal of Molecular Diagnostics.

16 Aug 2013

Trinity researchers reveal CHD5 protein acts as tumor suppressor in nervous system development

CHD5 has previously been proposed as a tumour suppressor, acting as a brake that prevents healthy cells from developing into cancer cells. But the part played by the protein in healthy tissue, and whether this role is important for its ability to counter tumour growth, has remained largely uncharted.

14 Aug 2013

Study shows metastasizing cancer cells undergo molecular change during EMT

For the majority of cancer patients, it's not the primary tumor that is deadly, but the spread or "metastasis" of cancer cells from the primary tumor to secondary locations throughout the body that is the problem. That's why a major focus of contemporary cancer research is how to stop or fight metastasis.

14 Aug 2013

Scientist develop mathematical model that predicts how individuals respond to cancer treatment

Vittorio Cristini, PhD, uses the example of an airplane to explain what he does in cancer research. "Before calculus," he says, "people couldn't really design a plane that would fly. You can do it by trial and error, but it would probably take centuries." Dr. Cristini has a faster way to try to understand cancer treatment. Like airplane designers today, he uses a mathematical model.

13 Aug 2013

Study provides clues to improve treatment of neuroblastoma with suppressor gene

Loss of a gene required for stem cells in the brain to turn into neurons may underlie the most severe forms of neuroblastoma, a deadly childhood cancer of the nervous system, according to a Ludwig Cancer Research study.

13 Aug 2013

Research suggests blocking DNA repair complex helps fight therapy-resistant leukemia

New research posted online by the Nature journal Leukemia suggests blocking part of a DNA repair complex that helps some types of leukemia resist treatment can increase the effectiveness of chemotherapy and enhance survival.

9 Aug 2013

NCI renews UCLA prostate SPORE grant

UCLA's Jonsson Comprehensive Cancer Center and the department of urology at the David Geffen School of Medicine at UCLA have been notified that their standing as a National Cancer Institute Specialized Program of Research Excellence site in prostate cancer has been renewed for another five years.

8 Aug 2013

Researchers identify mechanism responsible for loss of tumor-suppressor gene in soft-tissue sarcomas

Researchers have discovered a novel mechanism responsible for the loss of a critical tumor-suppressor gene in rhabdomyosarcoma and other soft-tissue sarcomas, rare cancers that strike mainly children and often respond poorly to treatment. Their cause is largely unknown.

8 Aug 2013

Observation time in ER is associated with reduced CT rates for children at risk of TBI

The longer a child with minor blunt head trauma is observed in the emergency department, the less likely the child is to require computed tomography (CT) scan, according to the results of a study published online Friday in Annals of Emergency Medicine ("Impact of the Duration of Emergency Department Observation on Computed Tomography Use in Children with Minor Blunt Head Trauma").

7 Aug 2013

Malignant News and Research

Study reports racial, ethnic differences in incidence of soft tissue sarcomas in young adults, adolescents

Scientists Shed New Light On Malignant Pancreatic Cancer

Scientists identify molecular mechanism that contributes to pancreatic cancer

People exposed to hot environments may develop Malignant hyperthermia

Oncopeptides launches phase II study to determine efficacy of melflufen in treatement of multiple myeloma

Multi-site trial shows BI-RADS 3 breast lesions reduce patient anxiety, unnecessary biopsies

Researchers identify key transcription factor linked with treatment-resistant prostate cancer

Evidence shows bevacizumab therapy improves survival in patients with glioblastoma

Report demonstrates clinical use of novel biomarker to assess cancer progression, inflammation

New antibodies estimate risk of polyps developing into bowel cancer

Researchers discover how common oral bacterium can contribute to colorectal cancer

German researchers discover miRNAs, which determine malignancy of urinary bladder cancers

Trinity researchers reveal CHD5 protein acts as tumor suppressor in nervous system development

Study shows metastasizing cancer cells undergo molecular change during EMT

Scientist develop mathematical model that predicts how individuals respond to cancer treatment

Study provides clues to improve treatment of neuroblastoma with suppressor gene

Research suggests blocking DNA repair complex helps fight therapy-resistant leukemia

NCI renews UCLA prostate SPORE grant

Researchers identify mechanism responsible for loss of tumor-suppressor gene in soft-tissue sarcomas

Observation time in ER is associated with reduced CT rates for children at risk of TBI

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