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Moderate radiation doses can kill premalignant cells and prevent second breast cancers

Survivors of breast cancer have a one in six chance of developing breast cancer in the other breast. But a study conducted in mice suggests that survivors can dramatically reduce that risk through treatment with moderate doses of radiation to the unaffected breast at the same time that they receive radiation therapy to their affected breast.

24 Jan 2014

Longer looks: Leaving antidepressants; the lack of tech-savvy doctors

Whenever I feel like taking a trip back in time, I save myself the trouble of building a time machine and instead just head over to a doctor's office. For a Millennial, or really anyone who lives a modern lifestyle, getting medical care is a rare departure from an otherwise technology-fueled existence. …

24 Jan 2014

Researchers discover mechanism that controls activity of LRRK2 in Parkinson's disease

In one variant of Parkinson's disease, the enzyme LRRK2 plays a central role. Scientists at the University of Kassel have now discovered a mechanism that controls the activity of LRRK2.

24 Jan 2014

Use of twice-daily pill could turn deadly blood cancer into highly treatable disease

Use of a twice-daily pill could turn a deadly blood cancer into a highly treatable disease, according to scientists at Weill Cornell Medical College who led a multinational research team.

24 Jan 2014

Scientists develop mathematical model to predict tumor behavior and personalized therapies

Dana-Farber Cancer Institute scientists have developed a mathematical model to predict how a patient's tumor is likely to behave and which of several possible treatments is most likely to be effective.

24 Jan 2014

NIDA releases guide on treating teen substance abuse

Resources to help parents, health care providers, and substance abuse treatment specialists treat teens struggling with drug abuse, as well as identify and interact with those who might be at risk, were released today by the National Institute on Drug Abuse.

24 Jan 2014

BRI receives grant to lead ITN for evaluating novel therapies for transplantation, allergy and autoimmune diseases

The National Institutes of Health has awarded Benaroya Research Institute at Virginia Mason a 7-year grant to lead the Immune Tolerance Network.

24 Jan 2014

Johns Hopkins researchers reveal how calcium is controlled in the body

Scientists at Johns Hopkins report they have figured out a key step in how “free” calcium — the kind not contained in bones — is managed in the body, a finding that could aid in the development of new treatments for a variety of neurological disorders that include Parkinson’s disease.

24 Jan 2014

USF Health receives $2.1M grant to study on new factors required for growth of malaria-related parasites

Animal cells similar to those of humans contain a "control room," called the centrosome, which regulates cell replication. Disrupt this core hub and you kill cell division.

24 Jan 2014

CUMC researchers identify gene that appears to play major role in motor neuron degeneration in ALS

Columbia University Medical Center researchers have identified a gene, called matrix metalloproteinase-9 (MMP-9), that appears to play a major role in motor neuron degeneration in amyotrophic lateral sclerosis, also known as Lou Gehrig's disease. The findings, made in mice, explain why most but not all motor neurons are affected by the disease and identify a potential therapeutic target for this still-incurable neurodegenerative disease. The study was published today in the online edition of the journal Neuron.

23 Jan 2014

ACM Global acquires Phoenix PCS to expand operation in the Asia Pacific region

ACM Global Central Laboratory, a diagnostic central laboratory specializing in delivering high quality testing services which optimize clinical trial outcomes, today announced it has acquired Phoenix Pharma Central Services Pte. Ltd, a premier central laboratory services provider for Asia Pacific clinical trials, with laboratory facilities in Singapore and Shanghai, China. The acquisition enables ACM Global to deliver increased operational and financial efficiencies to clients conducting clinical studies in the Asia Pacific region. Terms of the transaction were not disclosed.

23 Jan 2014

'Smart' holograms could be used to monitor diabetes, cardiac function, infections

Responsive holograms that change colour in the presence of certain compounds are being developed into portable medical tests and devices, which could be used to monitor conditions such as diabetes, cardiac function, infections, electrolyte or hormone imbalance easily and inexpensively.

23 Jan 2014

Researchers find definitive link between intimate partner violence and HIV risk

Researchers from The Miriam Hospital and the University of Rochester have found a definitive link between violence among intimate partners and an increased risk of HIV infection. The study is online in the journal Women & Health.

23 Jan 2014

Researchers discover new gene involved in severe childhood epilepsy

A European consortium of epilepsy researchers has reported the discovery of a new gene involved in severe childhood epilepsy. Using a novel combination of technologies, including trio exome sequencing of patient/parental DNA and genetic studies in the tiny larvae of zebrafish, the EuroEPINOMICS RES consortium found that mutations in the gene CHD2 are responsible for a subset of epilepsy patients with symptoms similar to Dravet syndrome - a severe form of childhood epilepsy that is in many patients resistant to currently available anti-epileptic drugs.

23 Jan 2014

Structural biologists advance efforts to develop new drugs targeting NMDA receptors in brain

Structural biologists at Cold Spring Harbor Laboratory (CSHL) and collaborators at Emory University have obtained important scientific results likely to advance efforts to develop new drugs targeting NMDA receptors in the brain.

23 Jan 2014

Starpharma receives approvals to commence phase 1 human clinical trial for DEP-Docetaxel

Starpharma today announced that it has received the necessary approvals to commence a phase 1 human clinical trial for its dendrimer-enhanced docetaxel (Taxotere®) chemotherapeutic product, referred to as DEP™-Docetaxel.

23 Jan 2014

Rice University scientists create new technique to widen bottleneck for pharmaceutical, other industries

Rice University scientists have created a way to fine tune a process critical to the pharmaceutical industry that could save a lot of time and money.

23 Jan 2014

MD Anderson collaborates with Johnson & Johnson to develop immunology-based cancer treatments

The University of Texas MD Anderson Cancer Center will collaborate with Johnson & Johnson Innovation, LLC, and its affiliate Janssen Biotech, Inc., to develop immunology-based cancer treatments through the MD Anderson Moon Shots Program immunotherapy platform.

23 Jan 2014

Scientists develop new genetic platform that yields novel antibiotic from ocean bacteria

Scientists at the University of California, San Diego have developed a new genetic platform that allows efficient production of naturally occurring molecules, and have used it to produce a novel antibiotic compound.

23 Jan 2014

Scientists give cautious welcome for new types of drug intended for use in place of antibiotics

New types of drug intended for use in place of antibiotics have been given a cautious welcome by scientists.

23 Jan 2014

Drugs News and Research

Moderate radiation doses can kill premalignant cells and prevent second breast cancers

Longer looks: Leaving antidepressants; the lack of tech-savvy doctors

Researchers discover mechanism that controls activity of LRRK2 in Parkinson's disease

Use of twice-daily pill could turn deadly blood cancer into highly treatable disease

Scientists develop mathematical model to predict tumor behavior and personalized therapies

NIDA releases guide on treating teen substance abuse

BRI receives grant to lead ITN for evaluating novel therapies for transplantation, allergy and autoimmune diseases

Johns Hopkins researchers reveal how calcium is controlled in the body

USF Health receives $2.1M grant to study on new factors required for growth of malaria-related parasites

CUMC researchers identify gene that appears to play major role in motor neuron degeneration in ALS

ACM Global acquires Phoenix PCS to expand operation in the Asia Pacific region

'Smart' holograms could be used to monitor diabetes, cardiac function, infections

Researchers find definitive link between intimate partner violence and HIV risk

Researchers discover new gene involved in severe childhood epilepsy

Structural biologists advance efforts to develop new drugs targeting NMDA receptors in brain

Starpharma receives approvals to commence phase 1 human clinical trial for DEP-Docetaxel

Rice University scientists create new technique to widen bottleneck for pharmaceutical, other industries

MD Anderson collaborates with Johnson & Johnson to develop immunology-based cancer treatments

Scientists develop new genetic platform that yields novel antibiotic from ocean bacteria

Scientists give cautious welcome for new types of drug intended for use in place of antibiotics

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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