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Rare DNA variations may be responsible for differences in susceptibility to common disorders

One-letter switches in the DNA code occur much more frequently in human genomes than anticipated, but are often only found in one or a few individuals. The abundance of rare variations across the human genome is consistent with the population explosion of the past few thousand years, medical geneticists and evolutionary biologists report in the May 17 advanced online edition of Science.

19 May 2012

The Millennium Village Project: a correction

Paul Pronyk, lead author of the Millennium Village paper, releases the following statement about the paper, Pronyk PM, Muniz M, Nemser B, et al, for the Millennium Villages Study Group. The effect of an integrated multisector model for achieving the Millennium Development Goals and improving child survival in rural sub-Saharan Africa: a non-randomised controlled assessment. Lancet 2012; published online May 8. DOI:10.1016/S0140-6736(12)60207-4.

18 May 2012

ACO model may improve populations-based outcomes for pain management

How will pain care be influenced by the anticipated reforms in the U.S. healthcare system? Current models of healthcare delivery offer both obstacles and opportunities for achieving quality and effectiveness in pain-related care, according to Daniel Carr, MD, Tufts University in his keynote address at the American Pain Society Annual Scientific Meeting.

18 May 2012

Regular eating times, extended daily fasting may prevent diabetes, obesity

It turns out that when we eat may be as important as what we eat. Scientists at the Salk Institute for Biological Studies have found that regular eating times and extending the daily fasting period may override the adverse health effects of a high-fat diet and prevent obesity, diabetes and liver disease in mice.

18 May 2012

Legislatures push health care changes in disabled, immigrant care, medical boards

State lawmakers grapple with health care issues including establishing a new monitor for disabled care in New York, avoiding cuts for undocumented immigrant care in D.C. and a Massachusetts revamp of the state medical board.

18 May 2012

First Edition: May 17, 2012

Today's headlines includes reports about the deadline set by the federal government regarding the creation of state-based health insurance exchanges.

17 May 2012

High-throughput sequencing can detect early signs of leukemia relapse

A study led by researchers at Fred Hutchinson Cancer Research Center has found that a next-generation, high-speed DNA-decoding technology called high-throughput sequencing can detect the earliest signs of potential relapse in nearly twice the number of leukemia patients as compared to flow cytometry, the current gold standard for detecting minimal residual disease.

17 May 2012

Immediate response required to curb spread of artemisinin-resistant malaria in Burma

In this Wall Street Journal opinion piece, Jay Winsten, associate dean at the Harvard School of Public Health, and Trish Stroman, a principal at the Boston Consulting Group, examine "the emergence in Southeast Asia of malarial parasites resistant to artemisinin -- the current gold-standard drug for treating the disease," writing it "poses grave new challenges."

17 May 2012

DSM needs radical change from current ‘field guide’ form

The Diagnostic and Statistical Manual of Mental Disorders (DSM), long the master reference work in psychiatry, is seriously flawed and needs radical change from its current "field guide" form, according to an essay by two Johns Hopkins psychiatrists published in the May 17 issue of the New England Journal of Medicine.

17 May 2012

Haitian government, health workers show commitment to nationwide vaccination campaign

In this post in the Huffington Post Blog, Dagfinn Hoybraten, vice president of the Norwegian Parliament and chair of the GAVI Alliance Board, examines a nationwide vaccination campaign in Haiti, through which "health officials are targeting measles, rubella and polio and [are] also introducing pentavalent vaccine, one shot against five diseases."

17 May 2012

U.S. HIV assistance through PEPFAR prevented 740,000 deaths between 2004-2008, study shows

"The lives of more than 740,000 people in nine African countries were saved between 2004 and 2008 by the U.S. President's Emergency Plan for AIDS Relief [PEPFAR]," according to a study conducted by Stanford University School of Medicine researchers and published in the Journal of the American Medical Association (JAMA) on Wednesday, HealthDay News reports.

17 May 2012

TRCARC, IBM partner to strengthen HIV prevention effort

IBM is collaborating with the Thai Red Cross AIDS Research Center (TRCARC) to strengthen HIV prevention effort and to make Bangkok the world's first city to achieve "Zero New HIV Infections" by 2015.

17 May 2012

No significant differences in absorption between tablet and softgel capsule forms of folic acid

The bioavailability of folic acid does not significantly differ between delivery in standard tablet or softgel capsule forms, according to research published in this month's Journal of the Academy of Nutrition and Dietetics. Folic Acid helps support a women's pregnancy and development of a healthy newborn.

17 May 2012

Early drug and alcohol use associated with lower levels of educational attainment

Researchers have found evidence that early drug and alcohol use is associated with lower levels of educational attainment.

17 May 2012

New insight into treatment patterns for people with stage two and three rectal cancer

Research from the University of Alberta provides new insight into treatment patterns for people with stage two and three rectal cancer-information that ultimately will help physicians improve care strategies for patients provincewide.

16 May 2012

Social networks influence beliefs regarding safety of influenza vaccines

College students' social networks influence their beliefs regarding the safety of influenza vaccines and decisions about vaccination, according to a new study in the Journal of Adolescent Health.

16 May 2012

World health statistics 2012 report puts spotlight on growing problem of NCD burden

The World health statistics 2012 report, released today, puts the spotlight on the growing problem of the noncommunicable diseases burden.

16 May 2012

Reuters examines use of statistics in public health ahead of WHO report

"Above all else, analyzing the state of the world's health -- be it by looking at obesity rates, cancer cases, malaria deaths, or HIV-free births -- requires decent statistics," Reuters reports in an article examining the use of statistics in public health ahead of the release of the WHO's World Health Statistics report.

16 May 2012

Reducing off-label antipsychotic use may generate savings with little impact on patient care

Reducing the non-FDA-approved use of antipsychotic drugs may be a way to save money while having little effect on patient care, according to a Penn State College of Medicine study.

16 May 2012

Micronutrients, early food supplementation during pregnancy improve survival of newborns

Pregnant women in poor communities in Bangladesh who received multiple micronutrients, including iron and folic acid combined with early food supplementation, had substantially improved survival of their newborns, compared to women in a standard program that included usual food supplementation, according to a study in the May 16 issue of JAMA, a theme issue on Global Health.

16 May 2012

Public Health News and Research

Rare DNA variations may be responsible for differences in susceptibility to common disorders

The Millennium Village Project: a correction

ACO model may improve populations-based outcomes for pain management

Regular eating times, extended daily fasting may prevent diabetes, obesity

Legislatures push health care changes in disabled, immigrant care, medical boards

First Edition: May 17, 2012

High-throughput sequencing can detect early signs of leukemia relapse

Immediate response required to curb spread of artemisinin-resistant malaria in Burma

DSM needs radical change from current ‘field guide’ form

Haitian government, health workers show commitment to nationwide vaccination campaign

U.S. HIV assistance through PEPFAR prevented 740,000 deaths between 2004-2008, study shows

TRCARC, IBM partner to strengthen HIV prevention effort

No significant differences in absorption between tablet and softgel capsule forms of folic acid

Early drug and alcohol use associated with lower levels of educational attainment

New insight into treatment patterns for people with stage two and three rectal cancer

Social networks influence beliefs regarding safety of influenza vaccines

World health statistics 2012 report puts spotlight on growing problem of NCD burden

Reuters examines use of statistics in public health ahead of WHO report

Reducing off-label antipsychotic use may generate savings with little impact on patient care

Micronutrients, early food supplementation during pregnancy improve survival of newborns

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