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COVID-19 may affect a group of biochemical reactions called one-carbon metabolism

A new study addresses the relationship between SARS-CoV-2 to the metabolism of one-carbon molecules in the host, suggesting new therapeutic pathways.

13 Apr 2022

Structural differences between SARS-CoV-1 and SARS-CoV-2 RBDs

A new study compares the SARS-CoV-2 RBD to the SARS-CoV RBD using computational methods to understand their binding affinities to ACE2.

13 Apr 2022

Gut microbes play a key role in regulating pancreas function, size and hormone secretion

Gut microbes can regulate the exocrine and endocrine functions of the pancreas and hormone production of the gastrointestinal tract, findings that may help develop potential treatments for diabetes and other diseases, a team of researchers from Boston College, Joslin Diabetes Center, and Maastricht University, Netherlands, report in the journal Diabetes.

13 Apr 2022

Scientific statement from the American Heart Association on COVID-19 and cardiovascular complications in children and adolescents

A recent scientific statement published in Circulation reviewed the current knowledge on COVID-19.

13 Apr 2022

mRNA vaccines induce CD8+ T cells that may reduce COVID-19 severity

In a recent study under consideration at Nature Portfolio Journal and posted to the Research Square* preprint server, researchers characterized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S)-specific cluster of differentiation 8 (CD8+) T cell responses.

12 Apr 2022

Antibody response following Omicron BA.2 infection is lower than BA.1

In a recent report posted to the medRxiv* preprint server, researchers determined immune responses generated by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.2 and BA.1 sublineage infections in prior virus-infected and naïve subjects.

12 Apr 2022

Development of 18 monoclonal antibodies against 9 SARS-CoV-2 proteins

A new study aimed to generate, characterize, and optimize Abs against SARS-CoV-2 proteins.

12 Apr 2022

Researchers discover new way to inhibit key mutated gene underlying tumor growth

CU Boulder researchers have discovered a new way to inhibit the most commonly mutated gene underlying human tumor growth, opening the door to new therapeutic strategies for cancer and a host of other diseases.

12 Apr 2022

Low-dose lithium attenuates kidney aging in mice

Best known therapeutically as a treatment for bipolar disorder, lithium has long intrigued researchers with its potential age-defying properties.

12 Apr 2022

Injection-free dermally delivered subunit vaccine strongly neutralizes SARS-CoV-2 variants

Researchers in Australia have evaluated the vaccine candidature of HexaPro S protein subunit vaccine against SARS-CoV-2.

12 Apr 2022

Decoy nanoparticles could provide a quick, effective treatment for COVID-19

They might look like cells and act like cells. But a new potential COVID-19 treatment is actually a cleverly disguised trickster, which attracts viruses and binds them, rendering them inactive.

12 Apr 2022

Heart complications uncommon for children and young adults after SARS-CoV-2 infection

Heart complications are uncommon, yet treatable for children and young adults after COVID-19 disease or SARS-CoV-2 infection, according to a new scientific statement from the American Heart Association that details what has been learned about how to treat, manage and even prevent cardiovascular complications from the SARS-CoV-2 virus in youth.

12 Apr 2022

Safety, reactogenicity, and immunogenicity of the BNT and half-m1273 mRNA COVID-19 vaccines given as a fourth dose booster

Researchers evaluated the immunogenicity of Pfizer’s BNT162b2 and Moderna’s mRNA-1273 vaccines offered as the fourth dose against SARS-CoV-2.

12 Apr 2022

NVX-CoV2373 vaccine found to induce functional SARS-CoV-2-specific T cell responses

In a recent study researchers evaluated the T cell responses elicited by full-length severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein vaccine NVX-CoV2373.

12 Apr 2022

Cryo-electron microscopy shows how Omicron BA.2 structure differs from BA.1 substantially

Researchers used cryogenic electron microscopy (cryo-EM) to determine the structure of the spike (S) protein of BA.2 sub-variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern (VOC) and compared them with previously determined S structures of Omicron's BA.1 sub-variant.

11 Apr 2022

Enzyme News and Research

COVID-19 may affect a group of biochemical reactions called one-carbon metabolism

Structural differences between SARS-CoV-1 and SARS-CoV-2 RBDs

Gut microbes play a key role in regulating pancreas function, size and hormone secretion

Scientific statement from the American Heart Association on COVID-19 and cardiovascular complications in children and adolescents

mRNA vaccines induce CD8+ T cells that may reduce COVID-19 severity

Antibody response following Omicron BA.2 infection is lower than BA.1

Development of 18 monoclonal antibodies against 9 SARS-CoV-2 proteins

Researchers discover new way to inhibit key mutated gene underlying tumor growth

Low-dose lithium attenuates kidney aging in mice

Injection-free dermally delivered subunit vaccine strongly neutralizes SARS-CoV-2 variants

Decoy nanoparticles could provide a quick, effective treatment for COVID-19

Heart complications uncommon for children and young adults after SARS-CoV-2 infection

Safety, reactogenicity, and immunogenicity of the BNT and half-m1273 mRNA COVID-19 vaccines given as a fourth dose booster

NVX-CoV2373 vaccine found to induce functional SARS-CoV-2-specific T cell responses

Cryo-electron microscopy shows how Omicron BA.2 structure differs from BA.1 substantially

Evidence of an increased risk of neurodegeneration after SARS-CoV-2 infection

Study identifies a novel class of angiotensin receptor blockers that interfere with SARS-CoV-2 spike – ACE2 interaction

Exploring evolutionary trajectories of SARS-CoV-2 interacting proteins in bats and primates

Ultralong bovine antibody targets cryptic and conserved epitope on SARS-CoV and SARS-CoV-2

Study explores phytochemical-based antivirals against SARS-CoV-2 infection

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