Mouse Model News and Research

RSS

Counteracting premature aging

Aging is the continuing process of such stress exposures, and with advancing age (normal aging), we must carry lots of senescent cells within our bodies. Senescent cells also often provide some ‘bad influences’ to surrounding healthy cells; such as chronic inflammation and tumorigenesis

14 Aug 2017

Researchers investigate genetic mutations in sperm cells to help prevent birth defects

It's about preventing birth defects. Associate pharmaceutical sciences professor Wenfeng An and his team at South Dakota State University are investigating mobile DNA segments, known as L1s, in sperm cells with the goal to treat families at risk for genetic mutations before they conceive.

10 Aug 2017

Researcher receives NIH grant to study genetic mutation that prevents tooth formation

Inherited genetic mutations can rob up to 7 percent of the population of their smile. Several genes are important for the placement and patterning of teeth.

9 Aug 2017

High-frequency alternating magnetic fields can help destroy bacterial biofilms

A short exposure to an alternating magnetic field might someday replace multiple surgeries and weeks of IV antibiotics as treatment for stubborn infections on artificial joints, new research suggests.

9 Aug 2017

Human gut microbe may help treat autoimmune diseases, say researchers

Mayo Clinic researchers, along with colleagues at the University of Iowa, report that a human gut microbe discovered at Mayo Clinic may help treat autoimmune diseases, such as multiple sclerosis. The findings appear in Cell Reports.

8 Aug 2017

Researchers find clues to how chemotherapy drug fuels cancer spread from the breast to lungs

The very same treatment that thwarts breast cancer has a dark side – it can fuel the spread of the disease to the lungs.

8 Aug 2017

JAX receives new federal research grant to study mouse models of ALS

A new five-year federal research grant totaling $3,322,009 to The Jackson Laboratory (JAX) will fund studies of a new mouse model for amyotrophic lateral sclerosis (ALS).

4 Aug 2017

Mouse model developed to allow study of Zika virus transmission

Scientists at the National Institutes of Health have developed a mouse model to study the sexual and fetal transmission of Zika virus. This will enable studies to further understanding of how the Zika virus spreads, thereby allowing treatments to be developed.

4 Aug 2017

Scientists propose therapeutic strategy to suppress formation of hereditary bony tumors

Patients with multiple hereditary exostoses (MHE)--a rare disease that causes the growth of multiple benign bone tumors -- have limited treatment options.

3 Aug 2017

Researchers develop potential stem cell treatment for several lung conditions

A team of scientists from the UNC School of Medicine and North Carolina State University has developed promising research towards a possible stem cell treatment for several lung conditions, such as idiopathic pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD), and cystic fibrosis -- often-fatal conditions that affect tens of millions of Americans.

3 Aug 2017

UCLA research in sarcoma provides much-needed roadmap for personalizing therapies

Sarcoma is a rare and deadly form of cancer occurring in the bones and connective tissue that affects individuals of all ages.

3 Aug 2017

Cell signaling molecules may be key to repairing diabetic nerve injury

Molecules that help cells communicate with each other--called cytokines--might be the key to repairing diabetic nerve damage, according to a new study published in Experimental Neurology. painful side effects.

1 Aug 2017

New substance restores brain function in Alzheimer's animal model

The protein amyloid beta is believed to be the major cause of Alzheimer's disease. Substances that reduce the production of amyloid beta, such as BACE inhibitors, are therefore promising candidates for new drug treatments.

28 Jul 2017

Estrogen uses certain cell type as 'mediator' for beneficial effects on the bone, research shows

The female sex hormone estrogen plays an important role in the structural stability of bones. To date, however, it had been unclear exactly which cells were involved in the hormone's protective function in preventing changes in bone density.

28 Jul 2017

Small-molecule drug improves brain performance in mouse model of Rett syndrome

After learning that a small-molecule drug improves breathing in a mouse model of the neurodevelopmental disorder Rett syndrome, University of Alabama at Birmingham researcher Lucas Pozzo-Miller, Ph.D., wondered if he could test it on other brain functions.

28 Jul 2017

Research suggests novel approach for encouraging regeneration in mouse retina

Cells within an injured mouse eye can be coaxed into regenerating neurons and those new neurons appear to integrate themselves into the eye's circuitry, new research shows.

27 Jul 2017

New compound takes positive step toward creating drug for melanoma

While past attempts to treat melanoma failed to meet expectations, an international team of researchers are hopeful that a compound they tested on both mice and on human cells in a petri dish takes a positive step toward creating a drug that can kill melanoma cancer cells without harming nearby healthy cells.

26 Jul 2017

Mouse Model News and Research

Counteracting premature aging

Researchers investigate genetic mutations in sperm cells to help prevent birth defects

Researcher receives NIH grant to study genetic mutation that prevents tooth formation

High-frequency alternating magnetic fields can help destroy bacterial biofilms

Human gut microbe may help treat autoimmune diseases, say researchers

Researchers find clues to how chemotherapy drug fuels cancer spread from the breast to lungs

JAX receives new federal research grant to study mouse models of ALS

Mouse model developed to allow study of Zika virus transmission

Scientists propose therapeutic strategy to suppress formation of hereditary bony tumors

Researchers develop potential stem cell treatment for several lung conditions

UCLA research in sarcoma provides much-needed roadmap for personalizing therapies

Cell signaling molecules may be key to repairing diabetic nerve injury

New substance restores brain function in Alzheimer's animal model

Estrogen uses certain cell type as 'mediator' for beneficial effects on the bone, research shows

Small-molecule drug improves brain performance in mouse model of Rett syndrome

Research suggests novel approach for encouraging regeneration in mouse retina

New compound takes positive step toward creating drug for melanoma

Scientists reveal communication system between knee joint and developing bones in mice

Neuro-oncology scientists discover unique molecular mechanism that maintains glioma stem cells

Established therapeutic drugs may be effective against childhood dementia

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Latest News