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Scientists identify new approach to fight malaria parasites

Using advanced methodologies that pit drug compounds against specific types of malaria parasite cells, an international team of scientists, including researchers at the University of California, San Diego School of Medicine and the Genomics Institute of the Novartis Research Foundation, have identified a potential new weapon and approach for attacking the parasites that cause malaria.

28 Nov 2013

Enzyme intervenes when cancer-fighting PTEN is bound for cell's protein-destroying machinery

A protector for PTEN, a tumor-thwarting protein often missing in cancer cells, has emerged from research led by scientists at The University of Texas MD Anderson Cancer Center published online at Nature Cell Biology this week.

28 Nov 2013

Researchers identify protein in malaria that is inhibited by newly discovered anti-malarial compounds

Researchers have identified the protein in malaria-causing Plasmodium parasites that is inhibited by a newly discovered class of anti-malarial compounds known as imidazopyrazines.

28 Nov 2013

Accumulation of small protein in brain’s blood vessels can drive early cognitive impairment

A team of Stony Brook University researchers led by William Van Nostrand, PhD, Professor in the Department of Neurosurgery, has discovered in a model of Alzheimer's disease that early accumulation of a small protein, known as amyloid β, in the blood vessels of the brain can drive early cognitive impairment.

28 Nov 2013

CRI researcher receives grant from DIPG to research on pediatric brain tumors

Javad Nazarian, PhD, a researcher with Children's Research Institute (CRI) at Children's National, is the recipient of a $99,979 grant from the DIPG Collaborative for his proposal entitled, "Comparative Proteomic and RNA Sequencing of DIPGs."

27 Nov 2013

Mutation in alpha-synuclein gene causes increased vulnerability to pesticides, leading to Parkinson's

A team of researchers has brought new clarity to the picture of how gene-environmental interactions can kill nerve cells that make dopamine. Dopamine is the neurotransmitter that sends messages to the part of the brain that controls movement and coordination.

27 Nov 2013

Brain research provides new clues to Pavlovian conditioning

Do fruit flies hold the key to treating dementia? Researchers at the University of Houston have taken a significant step forward in unraveling the mechanisms of Pavlovian conditioning. Their work will help them understand how memories form and, ultimately, provide better treatments to improve memory in all ages.

27 Nov 2013

Findings highlight possible new approach to combat malaria

An international team of scientists, including researchers at Columbia University Medical Center, has identified a key metabolic enzyme that common malaria parasites require for survival at each stage of infection in humans. The findings raise the possibility of a new approach to combating malaria, one of the world's deadliest diseases. The study was published today in the online edition of the journal Nature.

27 Nov 2013

Health benefits of eating almonds

As Americans sit down to enjoy Thanksgiving dinner, they often wish their family and friends good health and a long life. Good news! With nuts like almonds on the table, these sentiments are more than just a traditional toast.

27 Nov 2013

More nuts, more health benefits

In a large new study, observational researchers at Harvard University looked at how eating nuts may help reduce the risk of mortality, finding that those who ate nuts daily, such as pistachios, saw health benefits nearly double.

27 Nov 2013

DFG approves establishment of new Collaborative Research Centres

The Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) has approved the establishment of nine new Collaborative Research Centres (CRCs).

27 Nov 2013

Study uncovers mechanisms that allow stem cells to keep dividing in perpetuity

The blood stem cells that live in bone marrow are at the top of a complex family tree. Such stem cells split and divide down various pathways that ultimately produce red cells, white cells and platelets. These "daughter" cells must be produced at a rate of about one million per second to constantly replenish the body's blood supply.

27 Nov 2013

WHO releases new treatment guidelines for children suffering severe acute malnutrition

WHO today released new treatment guidelines for the almost 20 million children under-five worldwide who have severe acute malnutrition.

27 Nov 2013

Research: Motor proteins transport mRNA to get where it is needed, prevent diseases

Scientists have found that mRNA may travel one way down a cell, then board another, aptly named motor protein, and head in the opposite direction to get where it ultimately needs to be.

27 Nov 2013

Researchers show how unusual properties of A3G protein help fight HIV infection

A collaborative team led by a Northeastern University professor may have altered the way we look at drug development for HIV by uncovering some unusual properties of a human protein called APOBEC3G.

27 Nov 2013

Protecting or boosting neurotrophins may slow progression of Huntington's disease

A drug that acts like a growth-promoting protein in the brain reduces degeneration and motor deficits associated with Huntington's disease in two mouse models of the disorder, according to a study appearing November 27 in the Journal of Neuroscience. The findings add to a growing body of evidence that protecting or boosting neurotrophins - the molecules that support the survival and function of nerve cells - may slow the progression of Huntington's disease and other neurodegenerative disorders.

27 Nov 2013

CSHL identifies specific stretch of DNA that helps cancerous blood cells to proliferate in AML

A team of researchers at Cold Spring Harbor Laboratory (CSHL) has identified a leukemia-specific stretch of DNA called an enhancer element that enables cancerous blood cells to proliferate in Acute Myeloid Leukemia (AML), a devastating cancer that is incurable in 70% of patients.

27 Nov 2013

EU-funded project develops new type of vaccine to tackle HIV virus infection

AIDS research has attempted many strategies to tackle the HIV virus infection. Now, a new type of vaccine developed within an EU-funded project, called EuroNeut-41, is based on one of the envelope proteins of the HIV virus, called the gp41 protein. What makes it interesting it that it is directly responsible for the fusion of the HIV virus into human cells. By integrating the gp41 protein into the vaccine, researchers try to trigger the production of antibodies that would block the entrance of HIV into human cells

27 Nov 2013

Risk factors for Alzheimer's disease

Alzheimer's disease has joined cancer at the top of the list of feared diagnoses, and although Alzheimer's does have the potential to devastate millions of patients and families, there are reasons for hope - and possibly opportunities to reduce risk or alter the course of disease progression, according to Keith Black, MD, professor and chair of the Department of Neurosurgery at Cedars-Sinai.

26 Nov 2013

Researchers reveal why some breast cancer cells are resistant to chemotherapy

Researchers at the UNC School of Medicine, working with cell lines in a lab, have discovered why some of the most aggressive and fatal breast cancer cells are resistant to chemotherapy, and UNC scientists are developing ways to overcome such resistance.

26 Nov 2013

Protein C News and Research

Scientists identify new approach to fight malaria parasites

Enzyme intervenes when cancer-fighting PTEN is bound for cell's protein-destroying machinery

Researchers identify protein in malaria that is inhibited by newly discovered anti-malarial compounds

Accumulation of small protein in brain’s blood vessels can drive early cognitive impairment

CRI researcher receives grant from DIPG to research on pediatric brain tumors

Mutation in alpha-synuclein gene causes increased vulnerability to pesticides, leading to Parkinson's

Brain research provides new clues to Pavlovian conditioning

Findings highlight possible new approach to combat malaria

Health benefits of eating almonds

More nuts, more health benefits

DFG approves establishment of new Collaborative Research Centres

Study uncovers mechanisms that allow stem cells to keep dividing in perpetuity

WHO releases new treatment guidelines for children suffering severe acute malnutrition

Research: Motor proteins transport mRNA to get where it is needed, prevent diseases

Researchers show how unusual properties of A3G protein help fight HIV infection

Protecting or boosting neurotrophins may slow progression of Huntington's disease

CSHL identifies specific stretch of DNA that helps cancerous blood cells to proliferate in AML

EU-funded project develops new type of vaccine to tackle HIV virus infection

Risk factors for Alzheimer's disease

Researchers reveal why some breast cancer cells are resistant to chemotherapy

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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