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Submicrometer line focusing reduces protein crystal damage, enhances drug development

New recommendations for using X-rays promise to speed investigations aimed at understanding the structure and function of biologically important proteins - information critical to the development of new drugs.

20 Dec 2013

Five tips to identify individuals who may be vulnerable during holidays

While it is true that suicide rates are actually lower at the holidays compared to other times of the year, the holidays can be a very lonely time for those with nowhere to go and no one to turn to.

20 Dec 2013

ORIX USA Health partners with TGen and TD2 to support Arizona's biomedical economy

ORIX USA Health and Life Sciences has completed an investment into Translational Drug Development (TD2) through the purchase of equity from the Translational Genomics Research Institute (TGen).

20 Dec 2013

Viewpoints: Republicans' 'repeal trap;' 'insufferable' pajama boy; ADHD epidemic; ACLU's campaign against Catholic hospitals

The Journal Gazette of Fort Wayne, Indiana, reports on a fascinating exchange between GOP Rep. Marlin Stutzman and a local meat market owner, Lee Albright, who likes the Affordable Care Act and quizzed the Congressman about the real world implications of the GOP repeal stance (Greg Sargent, 12/18).

20 Dec 2013

State highlights: Calif. midwives prepare for new independence; Minn. gov supports nurse board changes; Colo. Medicaid dental care

California licensed midwives will have increased independence and authority in attending births, potentially giving more pregnant women access to their services under a new law that goes into effect in January. Assembly Bill 1308 removes an unworkable clause that required all licensed midwives to be supervised by a physician. Licensed midwives had been unable to fulfill that requirement since it went into effect 20 years ago because physicians' malpractice insurance prohibited them from filling that role. In addition, licensed midwives will now be authorized to operate birth centers without physician supervision and will have increased access to drugs, tests and medical devices used in their practice (Renner, 12/18).

20 Dec 2013

Boston College researchers combine two catalytic reactions to produce highly reactive compounds

Boston College chemists have developed a new chemical synthesis methodology that converts chemicals known as alpha-olefins into new organic compounds.

20 Dec 2013

Study supports mounting evidence that inflammation may be the cause of chronic rhinosinusitis

Saint Louis University researchers have analyzed the microbiomes of people with chronic rhinosinusitis and healthy volunteers and found evidence that some chronic sinus issues may be the result of inflammation triggered by an immune response to otherwise harmless microorganisms in the sinus membranes.

20 Dec 2013

People with diabetes at risk of developing diabetic macular edema during their lifetime

Despite recent advances in prevention and treatment of most vision loss attributed to diabetes, a new study shows that fewer than half of Americans with damage to their eyes from diabetes are aware of the link between the disease and visual impairment, and only six in 10 had their eyes fully examined in the year leading up to the study.

20 Dec 2013

Researchers identify molecular link between liver cancer, obesity, alcoholism, and hepatitis

Obesity, alcoholism, and chronic hepatitis all increase the risk of getting liver cancer, which is the third leading cause of cancer death worldwide. Obesity in particular is driving a significant increase in liver cancer in the United States.

20 Dec 2013

New research assesses nanomedicine-based approaches for treating cancer

As cancer maintains its standing as the second leading cause of death in the U.S., researchers have continued their quest for safer and more effective treatments. Among the most promising advances has been the rise of nanomedicine, the application of tiny materials and devices whose sizes are measured in the billionths of a meter to detect, diagnose and treat disease.

20 Dec 2013

Researchers discover cancer-killing properties of frankincense in ovarian cancer

Researchers from the University of Leicester have, for the first time, demonstrated the potential of treating ovarian cancer using the Christmas gift frankincense.

20 Dec 2013

Australian Therapeutic Goods Administration approves Genzyme's Lemtrada for multiple sclerosis

Genzyme, a Sanofi company, announced today that the Australian Therapeutic Goods Administration has approved Lemtrada (alemtuzumab) for the treatment of relapsing forms of multiple sclerosis for patients with active disease defined by clinical or imaging features to slow the accumulation of physical disability and reduce the frequency of clinical relapses.

19 Dec 2013

European research project to develop new rapid diagnostic devices

Led by the Basque R&D Alliance IK4, 13 organisations in 8 different countries have been conducting research for three years under the European LabOnFoil project to develop new rapid diagnostic devices.

19 Dec 2013

Viewpoints: New healthcare.gov czar knows something about computer bugs; fears about inadequate drug coverage

Seriously, one has to hope the new guy -- Kurt DelBene, former head of the Microsoft Office Division -- brings only a portion of Microsoft's heritage along with him. Aside from the XBox, the software giant isn't known for great consumer experiences. Its products have been maddeningly complex and notoriously buggy, at least in their early versions. Kind of like HealthCare.gov! (Jon Healey, 12/17).

19 Dec 2013

Bristol-Myers Squibb signs agreement to sell global diabetes business

Bristol-Myers Squibb Company today announced that it has signed an agreement to sell its global diabetes business that was part of its collaboration with AstraZeneca. Under terms of the agreement, AstraZeneca will make an upfront payment of $2.7 billion to Bristol-Myers Squibb, with potential regulatory- and sales-based milestone payments of up to $1.4 billion and will make royalty payments based on net sales through 2025.

19 Dec 2013

Computer-controlled, rotating table could deliver high doses of radiotherapy to tumors, spare vulnerable organs

Swivelling patients around on a computer-controlled, rotating table could deliver high doses of radiotherapy to tumours more quickly than current methods, while sparing vulnerable organs such as the heart, brain, eyes and bowel.

19 Dec 2013

UT Southwestern receives $10M grant to find effective treatments for alcoholic hepatitis

UT Southwestern Medical Center has launched the local arm of a national, multicenter study aimed at finding more effective treatments for alcoholic hepatitis, a disease of the liver that often leads to cirrhosis and death in severe cases.

19 Dec 2013

Sanofi and Regeneron Pharmaceuticals team up with ACC to enhance clinical research with alirocumab

Sanofi and Regeneron Pharmaceuticals, Inc. today announced an innovative collaboration with the American College of Cardiology focused on enhancing clinical research with alirocumab, an investigational monoclonal antibody targeting PCSK9 (proprotein convertase subtilisin/kexin type 9). PCSK9 is known to contribute to circulating low-density lipoprotein cholesterol (LDL-C) levels. Alirocumab is being co-developed by Sanofi and Regeneron.

19 Dec 2013

New guideline to help doctors treat patients with hypertension

A new guideline developed by evidence gathered from randomized clinical trials for the management of high blood pressure contains nine recommendations and a treatment algorithm to help doctors treat patients with hypertension.

19 Dec 2013

Researchers discover series of compounds possessing anti-HIV activity

University of Minnesota researchers have discovered a first-of-its-kind series of compounds possessing anti-human immunodeficiency virus (HIV) activity. The compounds present a new target for potential HIV drug development and future treatment options.

18 Dec 2013

Drugs News and Research

Submicrometer line focusing reduces protein crystal damage, enhances drug development

Five tips to identify individuals who may be vulnerable during holidays

ORIX USA Health partners with TGen and TD2 to support Arizona's biomedical economy

Viewpoints: Republicans' 'repeal trap;' 'insufferable' pajama boy; ADHD epidemic; ACLU's campaign against Catholic hospitals

State highlights: Calif. midwives prepare for new independence; Minn. gov supports nurse board changes; Colo. Medicaid dental care

Boston College researchers combine two catalytic reactions to produce highly reactive compounds

Study supports mounting evidence that inflammation may be the cause of chronic rhinosinusitis

People with diabetes at risk of developing diabetic macular edema during their lifetime

Researchers identify molecular link between liver cancer, obesity, alcoholism, and hepatitis

New research assesses nanomedicine-based approaches for treating cancer

Researchers discover cancer-killing properties of frankincense in ovarian cancer

Australian Therapeutic Goods Administration approves Genzyme's Lemtrada for multiple sclerosis

European research project to develop new rapid diagnostic devices

Viewpoints: New healthcare.gov czar knows something about computer bugs; fears about inadequate drug coverage

Bristol-Myers Squibb signs agreement to sell global diabetes business

Computer-controlled, rotating table could deliver high doses of radiotherapy to tumors, spare vulnerable organs

UT Southwestern receives $10M grant to find effective treatments for alcoholic hepatitis

Sanofi and Regeneron Pharmaceuticals team up with ACC to enhance clinical research with alirocumab

New guideline to help doctors treat patients with hypertension

Researchers discover series of compounds possessing anti-HIV activity

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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